25026-34-0 (4-氯苯乙酰氯,4-Chlorophenylacetyl chloride)

快速询单

结构式：

4-氯苯乙酰氯MOL文件

CAS号：

25026-34-0

中文名称：

4-氯苯乙酰氯

英文名称：

4-Chlorophenylacetyl chloride

安全信息：

分子式：

C₈H₆Cl₂O

分子量：

189.038640499115

4-氯苯乙酰氯(25026-34-0)名称与标识符

名称

中文别名：

4-氯苯乙酰氯;对氯苯乙酰氯;4-氯苯基乙酰基氯;4-Chlorophenylacetyl Chloride 4-氯苯乙酰氯;4-氯苯基乙酰氯;

英文别名：

2-(4-Chlorophenyl)acetyl chloride;4-Chlorophenylacetylchloride;TIMTEC-BB SBB005859;P-CHLOROPHENYLACETYL CHLORIDE;Benzeneacetyl chloride, 4-chloro-;4-Chlorobenzeneacetyl chloride;4-chlorophenylacetic acid chloride;parachlorophenyl acetyl chloride;4-Chlorophenylacetyl chloride;UMQUIRYNOVNYPA-UHFFFAOYSA-N;(4-chlorophenyl)acetyl chloride;4-Chlorobenzeneacetylchloride;4-chlorobenzenacetyl chloride;p-chlorophenyl-acetyl chloride;4-chlorophenyl acetyl chloride;4-c;4-chlorophenyl-acetyl chloride;(4-chlorophenyl)-acetyl chloride;MFCD00037111;SCHEMBL76050;4-chloro-phenylacetyl chloride;W-107269;4-Chloro Phenyl Acetyl Chloride;AKOS001322484;NS00027792;FT-0618249;Z217293314;S10930;2-(4-chlorophenyl)acetylchloride;F2190-0111;C2313;AS-54507;DTXSID10179736;(4-Chloro-phenyl)-acetyl chloride;EINECS 246-571-1;25026-34-0;EN300-25761;SY048421;(4-chlorophenyl)acetylchloride;AMY202100060;4-Chlorophenylacetyl chloride, 97%;DB-046606;

标识符

MDL：

MFCD00037111

InChIKey：

UMQUIRYNOVNYPA-UHFFFAOYSA-N

Inchi：

1S/C8H6Cl2O/c9-7-3-1-6(2-4-7)5-8(10)11/h1-4H,5H2

SMILES：

ClC1C=CC(=CC=1)CC(=O)Cl

BRN：

637775

4-氯苯乙酰氯(25026-34-0)物化性质

实验特性

LogP : 2.64790
PSA : 17.07000
折射率 : n20/D 1.5510(lit.)
沸点 : 129°C/15mmHg(lit.)
熔点 : No data available
闪点 : 华氏：>230 °F
摄氏：>110 °C
颜色与性状 : 未确定
溶解性 : 未确定
敏感性 : Moisture Sensitive
比旋光度 : -56.7 º
密度 : 1.292 g/mL at 25 °C(lit.)

计算特性

精确分子量 : 187.98000
氢键供体数量 : 0
氢键受体数量 : 1
可旋转化学键数量 : 2
同位素质量 : 187.98
重原子数量 : 11
复杂度 : 139
同位素原子数量 : 0
确定原子立构中心数量 : 0
不确定原子立构中心数量 : 0
确定化学键立构中心数量 : 0
不确定化学键立构中心数量 : 0
共价键单元数量 : 1
疏水参数计算参考值（XlogP） : 3.1
互变异构体数量 : 无
表面电荷 : 0
拓扑分子极性表面积 : 17.1

4-氯苯乙酰氯(25026-34-0)安全信息

符号： GHS05
WGK Germany： 3
安全术语： 8
安全说明： S26-S36/37/39-S45-S24/25
包装等级： II
包装类别： II
风险术语： R34
危险等级： 8
危险品标志： C
危险品运输编号： UN 3265 8/PG 2
危害声明：H302-H314-H317
警示性声明：P280-P305 + P351 + P338-P310
提示语：危险
储存条件： Store at 4°C,-4℃下存储更优
PackingGroup： II
危险类别码： 22-34-43
信号词： Danger
HazardClass： 8

4-氯苯乙酰氯(25026-34-0)国际标准相关数据

EINECS：

246-571-1

4-氯苯乙酰氯(25026-34-0)海关数据

海关编码：

2916399090

海关数据：

中国海关编码：

2916399090

概述：

2916399090 其他芳香一元羧酸. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

申报要素：

品名, 成分含量, 用途, 丙烯酸、丙烯酸盐或酯应报明包装

Summary：

2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

4-氯苯乙酰氯(25026-34-0)推荐厂家更多厂家(24)

公司名称	手机号/电话	联系人	QQ	询单
天门恒昌化工有限公司	15102714773 027-59322316	雷经理	1178380033	询单
上海源叶生物科技有限公司	15026964105 15026964105	汤思磊	2881489226	询单
江苏润丰合成科技有限公司	18662931390 0513-66017679	蔡经理	507167383	询单
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湖北永阔科技有限公司	18064098002 027-59223108	孙瑶	1248580055	询单
湖北万得化工有限公司	15827180502 027-59210159	陈丹丹	1148980033	询单
上海绩祥生物科技有限公司	13093077543	陆经理	3985448220	询单
南通众合化工新材料有限公司	18762756250 0513-55074056	胡经理	2369399482	询单

4-氯苯乙酰氯(25026-34-0)上下游

对氯苯乙酸乙酯 6-氯-3,4-二氢-1H-2-萘酮 4-氯苯乙酰肼

4-氯苯乙酰氯(25026-34-0)相关文献

1. Metal carbonyl mediated rearrangement of 5-(2-oxoalkyl)-1,2,4-oxadiazoles: synthesis of fully substituted pyrimidines
Ekaterina E. Galenko,Timur O. Zanakhov,Mikhail S. Novikov,Alexander F. Khlebnikov Org. Biomol. Chem. 2023 21 2990
2. Unprecedented intramolecular [3 + 2] cycloadditions of azido-ketenimines and azido-carbodiimides. Synthesis of indolo[1,2-a]quinazolines and tetrazolo[5,1-b]quinazolines
Mateo Alajarin,Baltasar Bonillo,Maria-Mar Ortin,Raul-Angel Orenes,Angel Vidal Org. Biomol. Chem. 2011 9 6741
3. Preparation and photochemistry of some chlorine-substituted derivatives of deoxybenzoin and bibenzyl
G. E. Robinson,J. M. Vernon J. Chem. Soc. Perkin Trans. 1 1972 1277
4. 635. Insecticidal activity and chemical constitution. Part V. Synthesis of some di-p-chlorophenylalkanes
E. John Skerrett,D. Woodcock J. Chem. Soc. 1952 3308
5. 320. Cyclic meso-ionic compounds. Part III. Further properties of the sydnones and the mechanism of their formation
Wilson Baker,W. D. Ollis,V. D. Poole J. Chem. Soc. 1950 1542
6. Triflic acid-mediated phenylation of N-acylaminoalkyl diethylacetals and N-acyl-2-phenyl cyclic amides
Frank D. King,Stephen Caddick Org. Biomol. Chem. 2011 9 4361
7. Synthesis of 1,3-diaryl-spiro[azetidine-2,3′-indoline]-2′,4-diones via the Staudinger reaction: cis- or trans-diastereoselectivity with different addition modes
Vadim Filatov,Maksim Kukushkin,Juliana Kuznetsova,Dmitry Skvortsov,Viktor Tafeenko,Nikolay Zyk,Alexander Majouga,Elena Beloglazkina RSC Adv. 2020 10 14122
8. Design, synthesis and biological evaluation of novel amide-linked 18β-glycyrrhetinic acid derivatives as novel ALK inhibitors
Dong Cai,Zhi hua Zhang,Yu Chen,Chao Ruan,Sheng qiang Li,Shi qin Chen,Lian shan Chen RSC Adv. 2020 10 11694

4-氯苯乙酰氯(25026-34-0)参考资料

Reaxys RN：

637775

Beilstein：

9(3)2264

PubChem CID：

87560909

4-氯苯乙酰氯(25026-34-0) MSDS

基础信息

Name:	4-Chlorobenzeneacetyl chloride 98% Material Safety Data Sheet
Synonym:	4-Chlorophenylacetyl chloride
CAS:	25026-34-0

Section 1 - Chemical Product ? MSDS Name:4-Chlorobenzeneacetyl chloride 98% Material Safety Data Sheet
Synonym:4-Chlorophenylacetyl chloride

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
25026-34-0	4-Chlorobenzeneacetyl chloride, 98%	98	246-571-1

Hazard Symbols: C
Risk Phrases: 34

Section 3 - HAZARDS IDENTIFICATION
? EMERGENCY OVERVIEW
Causes burns.Corrosive.
Potential Health Effects
Eye:
Causes eye burns. May cause chemical conjunctivitis and corneal damage.
Skin:
Causes skin burns. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
Ingestion:
May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. May cause perforation of the digestive tract. May cause systemic effects.
Inhalation:
May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema. Causes chemical burns to the respiratory tract. Aspiration may lead to pulmonary edema. May cause systemic effects.
Chronic:
Effects may be delayed.

Section 4 - FIRST AID MEASURES
? Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes).
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
? General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use agent most appropriate to extinguish fire.

Section 6 - ACCIDENTAL RELEASE MEASURES
? General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.

Section 7 - HANDLING and STORAGE
? Handling:
Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Discard contaminated shoes.
Storage:
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
? Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 25026-34-0: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
?
Physical State: Liquid
Color: red-pink
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C8H6Cl2O
Molecular Weight: 189.04

Section 10 - STABILITY AND REACTIVITY
? Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
? RTECS#:
CAS# 25026-34-0 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
4-Chlorobenzeneacetyl chloride, 98% - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION
?

Section 13 - DISPOSAL CONSIDERATIONS
? Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
?
IATA
Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
Hazard Class: 8
UN Number: 3265
Packing Group: II
IMO
Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
Hazard Class: 8
UN Number: 3265
Packing Group: II
RID/ADR
Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
Hazard Class: 8
UN Number: 3265
Packing group: II

Section 15 - REGULATORY INFORMATION
?
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 34 Causes burns.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 25026-34-0: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 25026-34-0 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 25026-34-0 is not listed on the TSCA inventory.
It is for research and development use only.

SECTION 16 - ADDITIONAL INFORMATION
N/A