34654-81-4 (6-[(3-氯丙基)氨基]-1,3-二甲基尿嘧啶,6-(3-Chloropropylamino)-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione)

快速询单

结构式：

6-[(3-氯丙基)氨基]-1,3-二甲基尿嘧啶MOL文件

CAS号：

34654-81-4

中文名称：

6-[(3-氯丙基)氨基]-1,3-二甲基尿嘧啶

英文名称：

6-(3-Chloropropylamino)-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione

安全信息：

分子式：

C₉H₁₄ClN₃O₂

分子量：

231.679360866547

API：

Urapidil

6-[(3-氯丙基)氨基]-1,3-二甲基尿嘧啶(34654-81-4)名称与标识符

名称

中文别名：

6-[(3-氯丙基)氨基]-1,3-二甲基尿嘧啶;6-((3-氯丙基)氨基)-1,3-二甲基尿嘧啶;6-(3-氯丙基)氨基-1,3-二甲基尿嘧啶;6-(3-氯丙基)氨基1,3-二甲基尿嘧啶;6-[(3-Chloropropyl)amino]-1,3-dimethyluracil 6-[(3-氯丙基)氨基]-1,3-二甲基尿嘧啶;乌拉地尔杂质1;乌拉地尔主链;6-(3-氯丙基)氨基1,3-二甲基脲嘧啶;6-[(3-氯丙基)氨基-1,3-二甲基尿嘧啶;

英文别名：

6-((3-Chloropropyl)amino)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione;6-[(3-Chloropropyl)amino]-1,3-dimethyluracil;6-(3-Chloropropylamino)-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione;2,4(1H,3H)-PYRIMIDINEDIONE, 6-[(3-CHLOROPROPYL)AMINO]-1,3-DIMETHYL-;6-(3-chloropropyl)amino-1,3-dimethyl-2,4(1h,3h)pyrimidinedione;6-(3-chloropropylamino)-1,3-dimethylpyrimidine-2,4-dione;6-(3-Chloropropylamino)-1,3-dimethyl uracil;6-(3-chloro-propylamino)-1,3-dimethyl-1H-pyrimidine-2,4-dione;EINECS 252-129-9;乌拉地尔主链;6-(3-Chloropropylamino)-1,3-dimethyluracil;6-((3-Chloropropyl)amino)-1,3-dimethyluracil;6-[(3-Chloropropyl)amino]-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione;6-(3-chloropropylamino)-1,3-dimethyl-pyrimidine-2,4-dione;6-((3-Chloropropyl)amino)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione;C2929;CS-0158719;6-[(3-chloropropyl)amino]-1 pound not3-dimethyluracil;6-(3-chloropropylamino)-1,3-dimethylpyrimidine-2,4(1h,3h)-dione;F15024;DTXSID20188213;AMY15304;NS00029702;FT-0664937;AS-12588;6-[(3-chloropropyl)amino]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione;EN300-4324363;34654-81-4;AKOS015850609;SB60526;MFCD00453355;SY024580;SCHEMBL7793927;A822332;6-{(3-Chloropropyl)amino-1,3-dimethuracil;RPYBDDBZRQGARJ-UHFFFAOYSA-N;6-[(3-CHLOROPROPYL)AMINO]-1,3-DIMETHYLPYRIMIDINE-2,4-DIONE;6-[(3-Chloropropyl)amino]-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione; 6-[(3-Chloropropyl)amino]-1,3-dimethyluracil;;72QGH8243D;6-(3-chloropropyl)-amino-dimethyluracil;

标识符

MDL：

MFCD00453355

InChIKey：

RPYBDDBZRQGARJ-UHFFFAOYSA-N

Inchi：

1S/C9H14ClN3O2/c1-12-7(11-5-3-4-10)6-8(14)13(2)9(12)15/h6,11H,3-5H2,1-2H3

SMILES：

ClCCCNC1=CC(N(C)C(N1C)=O)=O

6-[(3-氯丙基)氨基]-1,3-二甲基尿嘧啶(34654-81-4)物化性质

实验特性

LogP : 0.19780
PSA : 56.03000
折射率 : 1.56
沸点 : 342.9°C at 760 mmHg
熔点 : 156.0 to 160.0 deg-C
闪点 : 161.2±30.7 °C
颜色与性状 : No data available
密度 : 1.29

计算特性

精确分子量 : 231.07700
氢键供体数量 : 1
氢键受体数量 : 3
可旋转化学键数量 : 4
同位素质量 : 231.077
重原子数量 : 15
复杂度 : 304
同位素原子数量 : 0
确定原子立构中心数量 : 0
不确定原子立构中心数量 : 0
确定化学键立构中心数量 : 0
不确定化学键立构中心数量 : 0
共价键单元数量 : 1
疏水参数计算参考值（XlogP） : 0.5
拓扑分子极性表面积 : 52.6

6-[(3-氯丙基)氨基]-1,3-二甲基尿嘧啶(34654-81-4)安全信息

符号： GHS07
安全说明： H303吞入可能有害+H313皮肤接触可能有害+H333吸入可能对身体有害
危害声明：H315-H319
警示性声明：P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
提示语：警告
储存条件： Store at room temperature
信号词： Warning

6-[(3-氯丙基)氨基]-1,3-二甲基尿嘧啶(34654-81-4)国际标准相关数据

EINECS：

252-129-9

6-[(3-氯丙基)氨基]-1,3-二甲基尿嘧啶(34654-81-4)海关数据

海关编码：

2933599090

海关数据：

中国海关编码：

2933599090

概述：

2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

申报要素：

品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

Summary：

2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

6-[(3-氯丙基)氨基]-1,3-二甲基尿嘧啶(34654-81-4)推荐厂家更多厂家(67)

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6-[(3-氯丙基)氨基]-1,3-二甲基尿嘧啶(34654-81-4)上下游

6-氯-1,3-二甲基尿嘧啶

6-[(3-氯丙基)氨基]-1,3-二甲基尿嘧啶(34654-81-4)参考资料

Reaxys RN：

654801

PubChem CID：

253662382

6-[(3-氯丙基)氨基]-1,3-二甲基尿嘧啶(34654-81-4) MSDS

基础信息

6-[(3-Chloropropyl)amino]-1,3-dimethyluracil
SAFETY DATA SHEET

Section 1. IDENTIFICATION
Product name: 6-[(3-Chloropropyl)amino]-1,3-dimethyluracil

Section 2. HAZARDS IDENTIFICATION
  GHS classification
  PHYSICAL HAZARDS        Not classified
  HEALTH HAZARDS
  Skin corrosion/irritation        Category 2
    Category 2A
  Serious eye damage/eye irritation
  ENVIRONMENTAL HAZARDS        Not classified
  GHS label elements, including precautionary statements
  Pictograms or hazard symbols
  Signal word        Warning
  Hazard statements        Causes skin irritation
    Causes serious eye irritation
  Precautionary statements:
    Wash hands thoroughly after handling.
  [Prevention]
    Wear protective gloves/eye protection/face protection.
    IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses,
  [Response]
    if present and easy to do. Continue rinsing.
    If eye irritation persists: Get medical advice/attention.
    IF ON SKIN: Gently wash with plenty of soap and water.
    If skin irritation occurs: Get medical advice/attention.
    Take off contaminated clothing and wash before reuse.

Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
  Substance/mixture:        Substance
  Components:        6-[(3-Chloropropyl)amino]-1,3-dimethyluracil
  Percent:        >98.0%(HPLC)(N)
  CAS Number:        34654-81-4
  Chemical Formula:        C9H14ClN3O2

Section 4. FIRST AID MEASURES
Inhalation: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Get medical advice/attention if you feel unwell.

Section 4. FIRST AID MEASURES
  Skin contact:        Remove/Take off immediately all contaminated clothing. Gently wash with plenty of
    soap and water. If skin irritation or rash occurs: Get medical advice/attention.
  Eye contact:        Rinse cautiously with water for several minutes. Remove contact lenses, if present
    and easy to do. Continue rinsing. If eye irritation persists: Get medical
    advice/attention.
  Ingestion:        Get medical advice/attention if you feel unwell. Rinse mouth.
    A rescuer should wear personal protective equipment, such as rubber gloves and air-
  Protection of first-aiders:
    tight goggles.

Section 5. FIRE-FIGHTING MEASURES
  Suitable extinguishing        Dry chemical, foam, water spray, carbon dioxide.
  media:
  Specific hazards arising Take care as it may decompose upon combustion or in high temperatures to
  from the chemical:        generate poisonous fume.
  Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
    method according to the surrounding situation is used. Uninvolved persons should
    evacuate to a safe place. In case of fire in the surroundings: Remove movable
    containers if safe to do so.
  Special protective        When extinguishing fire, be sure to wear personal protective equipment.
  equipment for firefighters:

Section 6. ACCIDENTAL RELEASE MEASURES
  Personal precautions,        Use personal protective equipment. Keep people away from and upwind of spill/leak.
  protective equipment and Entry to non-involved personnel should be controlled around the leakage area by
  emergency procedures: roping off, etc.
  Environmental precautions: Prevent product from entering drains.
  Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it.
  containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with
  up: appropriate laws and regulations.

Section 7. HANDLING AND STORAGE
  Precautions for safe handling
  Technical measures:        Handling is performed in a well ventilated place. Wear suitable protective equipment.
    Prevent dispersion of dust. Wash hands and face thoroughly after handling.
    Use a local exhaust if dust or aerosol will be generated.
  Advice on safe handling: Avoid contact with skin, eyes and clothing.
  Conditions for safe storage, including any
  incompatibilities
  Storage conditions:        Keep container tightly closed. Store in a cool and dark place.
    Store away from incompatible materials such as oxidizing agents.
  Packaging material:        Comply with laws.

Section 8. EXPOSURE CONTROLS / PERSONAL PROTECTION
  Engineering controls:        Install a closed system or local exhaust as possible so that workers should not be
    exposed directly. Also install safety shower and eye bath.
  Personal protective equipment
  Respiratory protection: Dust respirator. Follow local and national regulations.
  Hand protection:        Protective gloves.
    Safety glasses. A face-shield, if the situation requires.
  Eye protection:
  Skin and body protection: Protective clothing. Protective boots, if the situation requires.

Section 9. PHYSICAL AND CHEMICAL PROPERTIES
  Physical state (20°C):        Solid
    Crystal- Powder
  Form:
  Colour:        White - Slightly pale yellow
    No data available
  Odour:

Section 9. PHYSICAL AND CHEMICAL PROPERTIES
  pH: No data available
  Melting point/freezing point:159°C
  Boiling point/range:        No data available
  Flash point:        No data available
  Flammability or explosive
  limits:
  Lower:        No data available
  Upper:        No data available
  Relative density:        No data available
  Solubility(ies):
  [Water]        No data available
  [Other solvents]        No data available

Section 10. STABILITY AND REACTIVITY
  Chemical stability:        Stable under proper conditions.
  Possibility of hazardous No special reactivity has been reported.
  reactions:
  Incompatible materials: Oxidizing agents
  Hazardous decomposition Carbon monoxide, Carbon dioxide, Nitrogen oxides (NOx), Hydrogen chloride
  products:

Section 11. TOXICOLOGICAL INFORMATION
  Acute Toxicity:        No data available
  Skin corrosion/irritation: No data available
  Serious eye        No data available
  damage/irritation:
  Germ cell mutagenicity: No data available
  Carcinogenicity:
    No data available
  IARC =
  NTP =        No data available
  Reproductive toxicity:        No data available

Section 12. ECOLOGICAL INFORMATION
  Ecotoxicity:
  Fish:        No data available
  Crustacea:        No data available
  Algae:        No data available
  Persistence / degradability: No data available
  Bioaccumulative        No data available
  potential(BCF):
  Mobility in soil
  Log Pow:        No data available
  Soil adsorption (Koc):        No data available
  Henry's Law        No data available
  constant(PaM3/mol):

Section 13. DISPOSAL CONSIDERATIONS
    Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material
    with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system.
    Observe all federal, state and local regulations when disposing of the substance.

Section 14. TRANSPORT INFORMATION
Hazards Class: Does not correspond to the classification standard of the United Nations
UN-No: Not listed

Section 15. REGULATORY INFORMATION
  Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002
  and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport,
    loading and unloading were prescribed.

SECTION 16 - ADDITIONAL INFORMATION
N/A