50-55-5 (利血平,Reserpine)

利血平;血安平;蛇根碱;白杨素;大青叶提取物;拉米夫定;利血平 EP标准品;利血平 USP标准品;利血平 标准品;利血平（标准品）;利血平, 来源于萝芙木属植物;利血平 植物提取物,标准品,对照品;利血平,分析标准品;利血平标准品(JP);萝芙木提取物;印度穆库尔没药（没药甾酮）;利舍平;蛇根草素;寿比安;利血平，利舍平，蛇根碱，血安平;利血平(对照品);

Reserpine;reserpine crystalline;3,4,5-Trimethoxybenzoyl methyl reserpate;Reserpine base;Resperine;​Reserpine;methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;RESERPINE(P) PrintBack;[3H]-Reserpine;Apoplon;Crystoserpine;Eskaserp;Hiserpia;methyl reserpate 3,4,5-trimethoxybenzoic acid ester;Raunervil;Raupasil;Raused;Rausedil;Reserpoid;Rivasin;Sandril;Serpalan;Serpanray;Serpasil;Serpivite;(3β, 16β, 17α, 18β, 20α)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester;3b,20a-Yohimban-16b-carboxylic acid, 18b-hydroxy-11,17a-dimethoxy- methyl ester 3,4,5-trimethoxybenzoate (ester)(8CI);3b,20a-Yohimban-16b-carboxylic acid,18b-hydroxy-11,17a-dimethoxy-, methyl ester, 3,4,5-trimethoxybenzoate(6CI);Benz[g]indolo[2,3-a]quinolizine, yohimban-16-carboxylic acid deriv.;(-)-Reserpine;11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acidmethyl ester;Anquil;Banasil;Bioserpine;Carpacil;Deserpine;ENT 50146;Elserpine;Eserpine;Hiposerpil;Kitine;Lemiserp;Loweserp;Mayserpine;Methylreserpate 3,4,5-trimethoxybenzoate (ester);NSC 237659;NSC 59272;Quiescin;Rau-sed;Raucap;Raulen;Raurine;Rausedyl;Rausingle;Rauwasedin;Resercaps;Resercen;Reserlor;Reserpamed;Reserpex;Reserpic acid methyl ester 3,4,5-trimethoxybenzoate (ester);Reserpil;Resine;Respital;Restran;Riserpa;Roxinoid;Sedaraupin;Sedserp;Serfin;Serolfia;Serp-AFD;Serpaloid;Serpasil Serpasol;Serpasil premix;Serpasol;Serpate;Serpen;Serpentina;Serpicon;Serpiloid;Serpine;Serpine (pharmaceutical);Serpipur;Sertabs;Sertina;T-Serp;Temposerpine;Triserpin;Vio-Serpine;Alserin;Hypersil;Enipresser;Helfoserpin;Eskaserpine;Rauserpine;Purserpine;Mephaserpin;Reserpanca;Maviserpin;Austrapine;Ascoserpina;Reserpal;Reserjen;Rautrin;Rauserpol;Raudixoid;Neoserp;Idsoserp;Hypersine;Escaspere;Apsical;A;Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-(3,4,5-trimethoxybenzoyl)oxy-, methyl ester, (3.beta.,16.beta.,17.alpha.,18.beta.,20.alpha.)-;Reserpine, certified reference material, TraceCERT(R);SMR000059122;NCGC00091250-03;Brinderdin;(3beta,16beta,17alpha,18beta,20alpha)-11,17-Dimethoxy-18- [(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxyl ic acid methyl ester;Reserpine, Pharmaceutical Secondary Standard; Certified Reference Material;IDI1_000012;Orthoserpina;Resperin;METHYL 18.BETA.-HYDROXY-11,17.ALPHA.-DIMETHOXY-3.BETA.,20.ALPHA.-YOHIMBAN-16.BETA.-CARBOXYLATE 3,4,5-TRIMETHOXYBENZOATE (ESTER).;Hydrosine 25;Naquival;Reserpene;RESERPINE [ORANGE BOOK];Metatensin #2;RESERPINE (MART.);Yohimban-16-carboxylic acid,11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester,(3b,16b,17a,18b,20a)-;Tri-Hydroserpine;Spectrum5_001415;Diupres 500;(1S,2R,3R,4aS,13bR,14aS)-methyl2,11-dimethoxy-3-((3,4,5-trimethoxybenzoyl)oxy)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate;Raugal;Rezerpin;Unilord;HMS2097P11;Benazyl;NCI60_004446;RESERPINE COMPONENT OF CAM-AP-ES;Tepserpine;Broserpine;HYDRO-SERP '25';Methyl reserpate 3,5-trimethyloxybenzoic acid;HYDROMOX R COMPONENT RESERPINE;RESERPINE COMPONENT OF SERPASIL-ESIDRIX;SW196458-3;UNM000011053801;Reserpine Standard for LC-MS, analytical standard, for LC-MS;(3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester;Raupoid;Methyl 18beta-hydroxy-11,17alpha-dimethoxy-3beta,20alpha-yohimban-16beta-carboxylate 3,4,5-trimethoxybenzoate (ester);methyl o-(3,4,5-trimethoxybenzoyl)reserpate;4-25-00-01319 (Beilstein Handbook Reference);Rauserpin;HMS1570P11;Serpivate;CHEBI:28487;RESERPINE COMPONENT OF NAQUIVAL;RESERPINE AND HYDROCHLOROTHIAZIDE-50;AMY591;RESERPINE [USP MONOGRAPH];Raumorine;KBio2_003117;Rawilid;Transerpin;Hypercal B;3beta,20alpha-yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-, methyl ester, 3,4,5-trimethoxybenzoate (ester);RESERPINE COMPONENT OF SER-AP-ES;Rausan;Reserpinum;Reserutin;Butiserpazide-25;Reserpur;RCRA waste no. U200;SBI-0050061.P004;Methylreserpate 3,4,5-trimethoxybenzoic acid;METHYL (3.BETA.,16.BETA.,17.ALPHA.,18.BETA.,20.ALPHA.)-11,17-DIMETHOXY-18-((3,4,5-TRIMETHOXYBENZOYL)OXY)YOHIMBAN-16-CARBOXYLATE;Sertens;Supergan;SCHEMBL2589;SER-AP-ES COMPONENT RESERPINE;Rolserp;Metatensin #4;Diurese-R;3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy- methyl ester 3,4,5-trimethoxybenzoate (ester);RESERPINE COMPONENT OF HYDROPRES;yohimban-16-carboxylic acid derivative of benz[g]indolo[2,3-a]quinolizine;Alkaserp;Serpilum;Seominal;Reserpine, crystallized, >=99.0% (HPLC);RESERPINE COMPONENT OF HYDRAP-ES;Pharmakon1600-01500526;Carrserp;HSDB 213;RENESE-R COMPONENT RESERPINE;Reserpin;Salupres;SERPASIL-APRESOLINE COMPONENT RESERPINE;Banisil;Lopac0_000073;METHYL 18beta-HYDROXY-11,17alpha-DIMETHOXY-3beta,20alpha-YOHIMBAN-16beta-CARBOXYLATE 3,4,5-TRIMETHOXYBENZOATE (ESTER).;DIUTENSEN-R COMPONENT RESERPINE;RESERPINE (USP-RS);HYDRAP-ES COMPONENT RESERPINE;Reserfia;H 520;methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyloxy)-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4(9),5,7-tetraene-19-carboxylate;component of Butiserpazide;(3?,16?,17?,18?,20?)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester;Apoplon (TN);gammaserpine;Trichlortensin;HMS3714P11;LP00073;UNII-8B1QWR724A;Benz[g]indolo[2, 1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-3-hydroxy-2,11-dimethoxy-, methyl ester, 3,4,5-trimethoxybenzoate;Methylreserpate 3,4,5-Trimethoxybenzoic acid ester;RESERPINE COMPONENT OF RENESE-R;Hexaplin;DB00206;Recipin;C33H40N2O9;C02AA02;V Serp;Resedrex;Terbolan;8B1QWR724A;BDBM50017712;Marnitension simple;CHEMBL772;Cardioserpin;METATENSIN COMPONENT RESERPINE;Reserpine [USP:INN:BAN:JAN];A913268;rese rpamed;reserpin-;methyl o-(3,4,5-trimethoxybenzo yl)reserpate;Hydroserpine Plus;Hydroserpalan;Resiatric;RESERPINE [MART.];RESERPINE COMPONENT OF UNIPRES;Diupres 250;Serpedin;Neoserfin;NCI-C50157;Z1251172867;:reserpine;Hiposepil;QEVHRUUCFGRFIF-MDEJGZGSSA-N;RESERPINE (EP MONOGRAPH);H.R.-50;HMS3260O07;Hypertane forte;DTXCID201237;Spectrum3_000894;ENT-50146;UNIPRES COMPONENT RESERPINE;MLS006011754;NINDS_000012;CCRIS 550;component of Naquival;NSC-59272;3-.beta., 18-.beta.-hydroxy-11,17-.alpha.-dimethoxy-,methyl ester, 3,4,5-trimethoxybenzoate (ester);NSC-237659;Methyl reserpate 3,4,5-trimethoxybenzoate (ester);Reserpidefe;HYDRO-RESERP COMPONENT RESERPINE;Renese R;Ascoserp;Trimethoxybenzoyl methyl reserpate;NCGC00091250-10;HMS2234E24;se rpate;KS-5106;Serpazil;Hydroserpine #1;MLS002154046;Tox21_111107;Sederaupin;Key-serpine;50-55-5 (free);Spectrum4_000989;Reserbal;Raunorine;RESERPINE COMPONENT OF HYDROSERPINE PLUS (R-H-H);BBL028800;Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-;HYDROCHLOROTHIAZIDE W/ RESERPINE;RESERPINE AND HYDROCHLOROTHIAZIDE;Q-100566;Resedril;Reserpka;RESERPINE COMPONENT OF HYDROMOX R;RESERPINE (IARC);HYDRO-RESERP;Hydropine;NCGC00259944-01;Serpentin;HYDRALAZINE HYDROCHLORIDE-HYDROCHLOROTHIAZIDE-RESERPINE COMPONENT RESERPINE;KBioGR_001397;REGROTON COMPONENT RESERPINE;SALUTENSIN COMPONENT RESERPINE;Serpena;Rauwiloid;Serathide;methyl dimethoxy-(3,4,5-trimethoxybenzoyl)oxy-[?]carboxylate;AC-34405;Reserp;C06539;Tensanyl;ACon1_000086;Hydropres 50;l -Carpserp;WLN: T F6 D5 C666 EM ON&&TTTJ HO1 SOVR CO1 DO1 EO1& TO1 UVO1;RESERPINE COMPONENT OF H.R.-50;RESERPINE COMPONENT OF DRALSERP;Rcra waste number U200;NSC59272;Rivased;HMS3884I21;79 more names available;RESERPINUM [HPUS];RESERPINE COMPONENT OF REGROTON;HMS1920P04;CS-1913;Salazide-Demi;Tensional;Veriloid;Hydropres 25;RESERPINE COMPONENT OF SER-A-GEN;Rausedan;V-Serp;NCGC00091250-12;Residin;KBio1_000012;RESERPINE [INN];DTXSID7021237;NSC237659;Chloroserp-250;RESERPINE COMPONENT OF METATENSIN;(3beta,16beta,17alpha,18beta,20alpha)-11,17-Dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)yohimban-16-carboxylic acid methyl ester;BRD-K95921201-001-07-0;SER-A-GEN COMPONENT RESERPINE;Hydro-Reserpine-25;HMS2092G05;Raunova;Prestwick_147;CAM-AP-ES COMPONENT RESERPINE;HYDRO-SERP '50';component of Regroton;Interpina;Tempo-Reserpina;NCGC00091250-06;RESERPINE COMPONENT OF SERPASIL-APRESOLINE;Reser-ar;3.beta., 18.beta.-hydroxy-11,17.alpha.-dimethoxy- methyl ester 3,4,5-trimethoxybenzoate (ester);BSPBio_000949;methyl (3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-{[(3,4,5-trimethoxyphenyl)carbonyl]oxy}yohimban-16-carboxylate;Rauwita;Serpasil-Esidrix #2;DRALSERP COMPONENT RESERPINE;NCGC00091250-01;Reserpine,(S);Serfolia;Diupres;Prestwick1_000875;3-beta,20-alpha-yohimban-16-beta-carboxylic acid, 18-beta-hydroxy-11,17-alpha-dimethoxy-, methyl ester,3,4,5-trimethoxybenzoate (ester);GTPL4823;Serpogen;3,5-Trimethoxybenzoyl methyl reserpate;R 0875;Rauwipur;Reserpine (JP17/USP/INN);Ebserpine;NCGC00091250-04;Pressimedin;Gilucard;NCGC00091250-05;Q407841;RESERPINE [MI];Solfo serpine;Residine;NCGC00091250-25;Tox21_500073;Eberpine;Reserpina [INN-Spanish];AI3-50146;methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-[(3,4,5-trimethoxyphenyl)carbonyloxy]-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate;Prestwick0_000875;RKL10049;SERPASIL-ESIDRIX COMPONENT RESERPINE;Tox21_300537;Rauserpin-Alk;Hypertensan;CCG-204168;Serpaneurona;Methyl reserpate; 3,4,5-Trimethoxybenzoic acid ester;VIXO;l'-Carpserp;Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-;NCGC00091250-07;Serpalan (TN);RESERPINE [EP MONOGRAPH];methyl 11,17alpha-dimethoxy-18beta-(3,4,5-trimethoxybenzoyloxy)-3beta,20alpha-yohimbane-16beta-carboxylate;EPA Pesticide Chemical Code 123101;methyl (3beta,16beta,17alpha,18beta,20alpha)-11,17-bis(methyloxy)-18-({[3,4,5-tris(methyloxy)phenyl]carbonyl}oxy)yohimban-16-carboxylate;Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester, (3.beta.,16.beta.,17.alpha.,18.beta.,20.alpha.)-;AC-13142;esc aspere;Reserpine [USAN:INN:BAN:JAN];DEMI-REGROTON COMPONENT RESERPINE;YOHIMBAN-16-CARBOXYLIC ACID,11,17-DIMETHOXY-18-((3,4,5-TRIMETHOXYBENZOYL)OXY)-, METHYL ESTER, (3BETA,16BETA,17ALPHA,18BETA,20ALPHA)-;BRN 0102014;RESERPINUM [WHO-IP LATIN];Hydromox R;neose rfin;HB1895;Roxynoid;Raudiford;Neoslowten;Hydro-Reserpine-50;(1S,2R,3R,4aS,13bR,14aS)-methyl 2,11-dimethoxy-3-((3,4,5-trimethoxybenzoyl)oxy)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate;Mallopress;KBio3_001808;Perskleran;methyl(1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;Idoserp;Darebon;Methyl (3R,16S,17R,18R,20S)-11,17-dimethoxy-18-(3,4,5-trimethoxybenzoyloxy)yohimban-16-carboxylate;Resaltex;RESERPINE [USP-RS];HYDROSERPINE PLUS (R-H-H) COMPONENT RESERPINE;Carditivo;NSC757309;LS-1306;Rauloydin;Serpil;(3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16- carboxylic acid methyl ester;AKOS000277559;Tylandril;Rauwoleaf;VI XO;Tensionorme;RESERPINE COMPONENT OF DEMI-REGROTON;R-e-s;SPBio_002870;KBio2_005685;RESERPINE [JAN];Reserpina;NCGC00091250-14;NAQUIVAL COMPONENT RESERPINE;Adelfan;SK-Reserpine;Chloroserpin-250;HMS3677D20;Serpazol;Spectrum_000109;Reserpine, European Pharmacopoeia (EP) Reference Standard;methyl (3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylate;Briserine;D00197;rau sedyl;Resocalm;Abesta;50-55-5;Ryser;Hydromox-R;Abicol;Hydro-Fluserpine #1;NCGC00091250-02;STK801975;3BETA,20ALPHA-YOHIMBAN-16BETA-CARBOXYLIC ACID, 18BETA-HYDROXY-11,17ALPHA-DIMETHOXY-, METHYL ESTER, 3,4,5-TRIMETHOXYBENZOATE;Tox21_202395;RESERPINE [WHO-IP];DivK1c_000012;RESERPINE [VANDF];Neo-antitensol;Prestwick2_000875;BR164333;Regroton;nembuserpin;Reserpine, United States Pharmacopeia (USP) Reference Standard;NCGC00091250-09;NCGC00091250-08;D0J4JM;RESERPINE [HSDB];KBioSS_000549;NCGC00254489-01;HY-N0480;methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyloxy)-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate;Chloroserpine-500;Rese-lar;Sandron;.gamma.-Serpine;Hydroserp;AB01562943_01;Serpasil-Esidrix #1;Rezide;Reserpine [USAN:BAN:INN:JAN];MFCD00005091;Usaf cb-27;methyl (1S,2R,3R,4aS,13bR,14aS)-2,11-dimethoxy-3-((3,4,5-trimethoxybenzoyl)oxy)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate;Sedaraupina;Rauvlid;component of Metatensin;3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-methyl ester 3,4,5-trimethoxybenzoate (ester);RESERPINE [IARC];CAS-50-55-5;Caswell No. 722A;METHYL (3beta,16beta,17alpha,18beta,20alpha)-11,17-DIMETHOXY-18-((3,4,5-TRIMETHOXYBENZOYL)OXY)YOHIMBAN-16-CARBOXYLATE;Serpoid;Rauwilid;Tox21_111107_1;neo-serp;MEGxp0_001904;Serpyrit;Elfanex;Serpazide;RESERPINE (USP MONOGRAPH);Tefaserpina;Tenserpinie;Adelphin;KBio2_000549;Modenol;3-beta,20-alpha-Yohimban-16-beta-carboxylic acid, 18-beta-hydroxy-11,17-alpha-dimethoxy-, methyl ester, 3,4,5-trimethoxybenzoate (ester);HMS3413D20;l-Carpserp;Klimanosid;Serpentil;Sertensin;Methyl reserpate 3,5-trimethoxybenzoic acid ester;RESERPINE COMPONENT OF DIUTENSEN-R;Prestwick3_000875;RESERPINE [WHO-DD];NCGC00260758-01;H.R.-50 COMPONENT RESERPINE;RESERPINE COMPONENT OF HYDRALAZINE HYDROCHLORIDE-HYDROCHLOROTHIAZIDE-RESERPINE;Raudixin;YOHIMBAN-16-CARBOXYLIC ACID, 11,17-DIMETHOXY-18-((3,4,5-TRIMETHOXYBENZOYL)OXY)-, METHYL ESTER, (3.BETA.,16.BETA.,17.ALPHA.,18.BETA.,20.ALPHA.)-;Roxel;RESERPINE COMPONENT OF SALUTENSIN;EN300-84477;BPBio1_001045;SDCCGSBI-0050061.P005;loweser p;Reserpine, 99%;Eberspine;Reserpine, Vetec(TM) reagent grade;Diutensen-R;NSC-757309;HYDROPRES COMPONENT RESERPINE;HMS500A14;EU-0100073;11,17-Dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)yohimban-16-carboxylic acid methyl ester;SPECTRUM1500526;Serpone;EINECS 200-047-9;Yohimban-16-carboxylic acid,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester, (3.beta.,16.beta.,17.alpha.,18.beta.,20.alpha.)-;Chloroserp-500;Alkarau;component of Renese R;Yohimban-16-carboxylic acid derivative of benz(g)indolo(2,3-a)quinolizine;3P Reserp;RESERPINE COMPONENT OF HYDRO-RESERP;NS00000355;Reserpine (USP:INN:BAN:JAN);methyl (4R)-11,17beta-dimethoxy-18beta-[(3,4,5-trimethoxybenzoyl)oxy]-3beta,20alpha-yohimban-16beta-carboxylate;Metatensin;Reserpina (INN-Spanish);Hydropres;Methyl (3R,16S,17R,18R,20S)-11,17-dimethoxy-18-(3,4,5-trimethoxybenzoyloxy)yohimban-16-carboxylate;Folium Isatidis Extract;BRD-K95921201-001-15-3;Reserpine?;BRD-K95921201-001-12-0;BRD-K95921201-001-13-8;BRD-K95921201-001-14-6;Reserpine (JP18/USP/INN);FR09862;Reserpine (Standard);Reserpine - Bio-X trade mark;HY-N0480R;AE-508/21131019;AJ-160/21107004;200-047-9;

MFCD00005091

QEVHRUUCFGRFIF-MDEJGZGSSA-N

1S/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1

O(C)[C@H]1[C@@H](C[C@@H]2CN3CCC4C5C=CC(=CC=5NC=4[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC)OC(C1C=C(C(=C(C=1)OC)OC)OC)=O

102014

200-047-9

一，该品系由夹竹桃科植物（萝芙木属）全碱浓缩酸性渗透漉液时析出的胶瘃物中提取而得的一种生物碱，由化学合成来制取。但目前合成法尚无工来生产价值，均自萝芙木中提取。取萝芙木酸性渗漉液蒸发浓缩时析出的胶状物质，加乙醇、冰乙酸、获得酸性乙醇溶液，再用氯仿提取得到氯仿溶液，将基利血平转成硝酸盐，再在弱碱性溶液中以丙酮萃取，并经精制而得利血平。由于该品极易氧化变质，整个生产过程均须避光进行。对生药计总收率约0.01%，对胶质计约0.5%。 

二，生物合成

色氨酸是利血平的生物合成途径的起始原料。色氨酸被色氨酸脱羧酶(tryptophandecarboxylase)转化为色胺。色胺在异胡豆苷合成酶(strictosidinesynthetase)的催化下结合裂环马钱子苷(secologanin)合成异胡豆苷(strictosidine)。多种酶催化反应最终使异胡豆苷转化成利血平。

三，全合成

虽然从萝芙木中已可提取出高纯的利血平，全合成生产也是可行的。1958年，伍德沃德成功地以十六步以上反应全合成利血平，成为有机化学的一块里程碑。由于其结构复杂，它已经成为经典化合物，并已成为众多全合成反应的目标，一些替代的方案也不断被发展出来。1989年，利血平立体构象的全合成也被完成。  

102015

102014