52009-14-0 (丙酮酸钙,Calcium pyruvate)

CAS号:
52009-14-0
中文名称:
丙酮酸钙
英文名称:
Calcium pyruvate
分子式:
C6H6CaO6
分子量:
214.18624162674
简介:
丙酮酸钙是 丙酮酸 的钙盐。丙酮酸钙作为膳食补充剂,具有加速脂肪消耗、减轻体重、增强人体耐力、提高竞技成绩等功效;对心脏有特殊的保护作用,可增强心脏肌肉的效能,减少心脏病或心脏局部缺血造成的损伤;同时,丙酮酸钙具有吞噬体内自由基和抑制自由基的生成等显著效果。
相关分类:

丙酮酸钙(52009-14-0)名称与标识符

名称

中文别名:
丙酮酸钙;丙酮酸钙, 无水;2-氧代丙酸钙盐;焦葡萄酸钙;丙酮酸钙,AR;枸杞提取物;
英文别名:
Calcium Pyruvate;PYRUVIC ACID CALCIUM SALT;CALCIUM PYRUVIC;2-oxo-propanoic acid calcium salt;Pyruvate (Ca,Mg,Na,Etc);Pyruvic acid calcium;Caclium pyruvate;Calcim pyruvate;Barbury Wolfberry fruit P.E.;Acetamide, 2,2,2-trichloro-N-(4-fluorophenyl)-;AKOS015963184;Calcium pyruvate, anhydrous;SCHEMBL240885;MFCD00037199;H11289;Calcium2-oxopropanoate;9V2CQZ19N4;NS00089685;AMY25702;AC-20029;Propanoic acid, 2-oxo-, calcium salt (2:1);Calcium 2-oxopropanoate;FT-0640040;SY110792;Q27273262;AKOS015901775;DTXSID30199976;EINECS 257-599-9;calcium 2-oxidanylidenepropanoate;Calcium Pyruvate (Technical Grade);52009-14-0;BCP13503;A828881;Propanoic acid, 2-oxo-, calcium salt;Pyruvic acid calcium salt, anhydrous;calcium;2-oxopropanoate;CALCIUM PYRUVATE [WHO-DD];UZWMCCLZMHPPKW-UHFFFAOYSA-L;UNII-9V2CQZ19N4;AS-12630;Wolfberry Extract;Pyruvic Ion inverted exclamation markY 60.0%;DTXCID90122467;

标识符

MDL:
MFCD00037199
InChIKey:
UZWMCCLZMHPPKW-UHFFFAOYSA-L
Inchi:
1S/2C3H4O3.Ca/c2*1-2(4)3(5)6;/h2*1H3,(H,5,6);/q;;+2/p-2
SMILES:
[Ca+2].O=C(C(=O)[O-])C.O=C(C(=O)[O-])C

丙酮酸钙(52009-14-0)物化性质

实验特性

  • LogP : -3.34940
  • PSA : 114.40000
  • 沸点 : 165ºC at 760 mmHg
  • 熔点 : >330°C
  • 蒸气压 : No data available
  • 闪点 : 1 °F
  • 颜色与性状 : 白色粉末
  • 溶解性 : 未确定
  • 密度 : 1.031 g/mL at 25 °C
  • 水溶解性 : 剧烈反应

计算特性

  • 精确分子量 : 213.97900
  • 氢键供体数量 : 0
  • 氢键受体数量 : 6
  • 可旋转化学键数量 : 2
  • 同位素质量 : 213.979
  • 重原子数量 : 13
  • 复杂度 : 78.5
  • 同位素原子数量 : 0
  • 确定原子立构中心数量 : 0
  • 不确定原子立构中心数量 : 0
  • 确定化学键立构中心数量 : 0
  • 不确定化学键立构中心数量 : 0
  • 共价键单元数量 : 3
  • 疏水参数计算参考值(XlogP) : 无
  • 互变异构体数量 : 3
  • 表面电荷 : 0
  • 拓扑分子极性表面积 : 114

丙酮酸钙(52009-14-0)国际标准相关数据

EINECS:
257-599-9

丙酮酸钙(52009-14-0)海关数据

海关数据:

中国海关编码:

2918300090

概述:

2918300090 其他含醛基或酮基不含其他含氧基羧酸(包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物). 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%

申报要素:

品名, 成分含量, 用途

Summary:

2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

丙酮酸钙(52009-14-0)生产方法和用途

用途:

一,用作医药的原料和食品添加剂

      丙酮酸钙作为膳食补充剂,具有加速脂肪消耗、减轻体重、增强人体耐力、提高竞技成绩等功效;对心脏有特殊的保护作用,可增强心脏肌肉的效能,减少心脏病或心脏局部缺血造成的损伤;同时,丙酮酸钙具有吞噬体内自由基和抑制自由基的生成等显著效果。

二,减肥清脂
      丙酮酸钙进入机体内首先被胃分泌的盐酸置换为弱性有机酸-丙酮酸(分子量为88),极易透过细胞膜而进入细胞内,通过渗透作用到达机体细胞的能量加工厂-线粒体,将运进来的脂肪酸(主要是长链型)氧化燃烧供能,机体宏观表现为脂肪减少、体重减轻。美国匹兹堡大学医学研究中心的科学试验结果让人惊讶:丙酮酸钙可以增加至少48%的脂肪消耗。

三,用于医药、氨基酸(L-酪氨酸的底物)等的合成,可提高效率,特别是在制药工业方面可缩短流程,简化流程,例如用本品制成的2-苯基辛可宁酸,是一种解热镇痛、利尿药,采用本品为原料,可大大降低生产成本;

四,用作抗结核药、异菸肼丙酮酸钙、激素的合成,驱虫剂扑绕灵(Pyrunium pamote)的原料

五,用于农药原料;以丙酮酸、吲哚和氨为原料,进行生化反应,可制造色氨酸;生产味精,为提高L-苏氨酸的产率,可采用本品

六,香料,是我国GB2760—1996规定允许使用的食用香料。

生产方法:

一,以乳酸酯为原料进行气相或液相氧化制得丙酮酯,进一步水解可制得。

二,以酒石酸为原料,在其中加入硫酸氢钾和硫酸氢钠,加热至210~220℃,脱氢,可得丙酮酸粗品,再利用减压精馏精制。

三,以2,2-二氯丙酸为原料,采用****,调节pH=6左右,进行水解,可制得。

丙酮酸钙(52009-14-0)推荐厂家 更多厂家(128)

丙酮酸钙(52009-14-0)谱图信息

1H NMR300 MHzDMSO
1H NMR
13C NMR
13C NMR

丙酮酸钙(52009-14-0)相关文献

丙酮酸钙(52009-14-0)参考资料

Beilstein:
MFCD00037199
PubChem CID:

丙酮酸钙(52009-14-0) MSDS

基础信息


Section 1. Chemical Product and Company Identification
    Calcium pyruvate        Catalog    
    C2262, YY373
    Common Name/
    Number(s).
    Trade Name
    CAS#        52009-14-0    
    Manufacturer
    RTECS        Not available.    
    SPECTRUM CHEMICAL MFG. CORP.
    TSCA        TSCA 8(b) inventory: No    
    products were found.
    Commercial Name(s)        Not available.    
    CI# Not available.
    Synonym        Not available.    
    IN CASE OF EMERGENCY
    Not available.
    Chemical Name
    Chemical Family        Not available.        CALL (310) 516-8000    
    C6H6O6Ca.xH2O
    Chemical Formula
    SPECTRUM CHEMICAL MFG. CORP.

Section 2.Composition and Information on Ingredients
    Exposure Limits
    TWA (mg/m3)        STEL (mg/m3) CEIL (mg/m3)    
    Name        CAS #        % by Weight    
    1) Calcium pyruvate        52009-14-0        100    
    Toxicological Data        Calcium pyruvate    
    on Ingredients        LD50: Not available.    
    LC50: Not available.

Section 3. Hazards Identification
    Potential Acute Health Effects Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation (lung irritant).
    Slightly hazardous in case of skin contact (permeator).
    Potential Chronic Health        CARCINOGENIC EFFECTS: Not available.    
    Effects        MUTAGENIC EFFECTS: Not available.    
    TERATOGENIC EFFECTS: Not available.
    DEVELOPMENTAL TOXICITY: Not available.
    Repeated or prolonged exposure is not known to aggravate medical condition.
    Calcium pyruvate

Section 4. First Aid Measures
    Eye Contact        Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes,    
    keeping eyelids open. Cold water may be used. Do not use an eye ointment. Seek medical attention.
    Skin Contact        After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin    
    with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin.
    Cold water may be used. Cover the irritated skin with an emollient. If irritation persists, seek medical attention.
    Wash contaminated clothing before reusing.
    Serious Skin Contact        Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical    
    attention.
    Inhalation        Allow the victim to rest in a well ventilated area. Seek immediate medical attention.    
    Serious Inhalation        Not available.    
    Ingestion        Do not induce vomiting. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not    
    breathing, perform mouth-to-mouth resuscitation. Seek immediate medical attention.
    Serious Ingestion        Not available.    

Section 5. Fire and Explosion Data
    Flammability of the Product May be combustible at high temperature.
    Auto-Ignition Temperature Not available.
    Flash Points        Not available.    
    Flammable Limits        Not available.    
    These products are carbon oxides (CO, CO2). Some metallic oxides.
    Products of Combustion
    Fire Hazards in Presence of Not available.
    Various Substances
    Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
    of Various Substances        Risks of explosion of the product in presence of static discharge: Not available.    
    Fire Fighting Media        SMALL FIRE: Use DRY chemical powder.    
    and Instructions        LARGE FIRE: Use water spray, fog or foam. Do not use water jet.    
    Special Remarks on        Not available.    
    Fire Hazards
    Special Remarks on Explosion Not available.
    Hazards

Section 6. Accidental Release Measures
    Small Spill        Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by    
    spreading water on the contaminated surface and dispose of according to local and regional authority
    requirements.
    Large Spill
    Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water
    on the contaminated surface and allow to evacuate through the sanitary system.
    Calcium pyruvate

Section 7. Handling and Storage
    Precautions        Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the    
    residue under a fume hood. Ground all equipment containing material. Do not breathe dust. Wear suitable
    protective clothing In case of insufficient ventilation, wear suitable respiratory equipment If you feel unwell, seek
    medical attention and show the label when possible. Avoid contact with skin and eyes
    Storage        Keep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightly    
    closed. Keep in a cool, well-ventilated place. Combustible materials should be stored away from extreme heat
    and away from strong oxidizing agents.

Section 8. Exposure Controls/Personal Protection
    Engineering Controls        Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below    
    recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
    airborne contaminants below the exposure limit.
    Personal Protection        Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.    
    Gloves.
    Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
    a Large Spill        to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist    
    BEFORE handling this product.
    Exposure Limits        Not available.    

Section 9. Physical and Chemical Properties
    Physical state and appearance Solid.        Odor        Not available.    
    Taste        Not available.    
    214.19 g/mole
    Molecular Weight
    Color        Off-white.    
    pH (1% soln/water)        Not available.    
    Boiling Point        Not available.    
    Melting Point        Decomposes. (150°C or 302°F)    
    Critical Temperature        Not available.    
    Specific Gravity        Not available.    
    Not applicable.
    Vapor Pressure
    Vapor Density        Not available.    
    Volatility        Not available.    
    Odor Threshold        Not available.    
    Water/Oil Dist. Coeff.        Not available.    
    Not available.
    Ionicity (in Water)
    Dispersion Properties        See solubility in water.    
    Partially soluble in cold water.
    Solubility

Section 10. Stability and Reactivity Data
    The product is stable.
    Stability
    Instability Temperature        Not available.    
    Not available.
    Conditions of Instability
    Incompatibility with various Not available.
    substances
    Calcium pyruvate
    Corrosivity        Non-corrosive in presence of glass.    
    Special Remarks on        Not available.    
    Reactivity
    Special Remarks on        Not available.    
    Corrosivity
    Polymerization        No.    

Section 11. Toxicological Information
    Routes of Entry        Absorbed through skin. Dermal contact. Eye contact. Inhalation. Ingestion.    
    Toxicity to Animals        LD50: Not available.    
    LC50: Not available.
    Chronic Effects on Humans Not available.
    Other Toxic Effects on        Hazardous in case of skin contact (irritant), of ingestion, of inhalation (lung irritant).    
    Humans        Slightly hazardous in case of skin contact (permeator).    
    Special Remarks on        Not available.    
    Toxicity to Animals
    Special Remarks on        Not available.    
    Chronic Effects on Humans
    Special Remarks on other        Not available.    
    Toxic Effects on Humans

Section 12. Ecological Information
    Ecotoxicity        Not available.    
    BOD5 and COD        Not available.    
    Products of Biodegradation        Possibly hazardous short term degradation products are not likely. However, long term degradation products may    
    arise.
    Toxicity of the Products        The products of degradation are more toxic.    
    of Biodegradation
    Special Remarks on the        Not available.    
    Products of Biodegradation

Section 13. Disposal Considerations
    Waste Disposal

Section 14. Transport Information
    DOT Classification        Not a DOT controlled material (United States).    
    Identification        Not applicable.    
    Special Provisions for        Not applicable.    
    Transport
    Calcium pyruvate
    DOT (Pictograms)

Section 15. Other Regulatory Information and Pictograms
    TSCA 8(b) inventory: No products were found.
    Federal and State
    Regulations
    California        California prop. 65: This product contains the following ingredients for which the State of California has found    
    to cause cancer which would require a warning under the statute: No products were found.
    Proposition 65
    Warnings
    California prop. 65: This product contains the following ingredients for which the State of California has found
    to cause birth defects which would require a warning under the statute: No products were found.
    Other Regulations        Not available..    
    WHMIS (Canada) Not controlled under WHMIS (Canada).
    Other Classifications
    DSCL (EEC)        R36/37/38- Irritating to eyes,    
    respiratory system and skin.
    Health Hazard
    HMIS (U.S.A.)        2 National Fire Protection    
    1 Flammability
    1 Association (U.S.A.)
    Fire Hazard
    2 0 Reactivity
    Health
    Reactivity
    0
    Specific hazard
    Personal Protection
    E
    WHMIS (Canada)
    (Pictograms)
    DSCL (Europe)
    (Pictograms)
    TDG (Canada)
    (Pictograms)
    ADR (Europe)
    (Pictograms)
    Protective Equipment
    Gloves.
    Lab coat.
    Dust respirator. Be sure to use an
    approved/certified respirator or
    equivalent.
    Calcium pyruvate


SECTION 16 - ADDITIONAL INFORMATION
N/A