76-43-7 (氟甲睾酮,Fluoxymesterone)

CAS号:
76-43-7
中文名称:
氟甲睾酮
英文名称:
Fluoxymesterone
分子式:
C20H29FO3
分子量:
336.440870046616
简介:
氟甲睾酮药理作用与睾酮相似,但在体内分解缓慢,作用持久,其雄激素较睾酮强10倍,其蛋白同化作用则强20倍。

氟甲睾酮(76-43-7)名称与标识符

名称

中文别名:
氟甲睾酮;氟羟甲基睾丸酮;醋酸氯睾酮;氟甲睾酮 标准品;氟甲睾酮标准品(JP);氟羟甲睾酮;氟氧睾酮;甲睾酮;氟羟甲基睾酮;氟羟甲基睾丸素;龙坦特伦;
英文别名:
Fluoxymesterone;9a-Fluoro-11b,17b-dihydroxy-17a-methyl-4-androsten-3-one;(8S,9R,10S,11S,13S,14S,17S)-9-fluoro-11,17-dihydroxy-10,13,17-trimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one;Fluoxymesterone solution;FLUOXYMESTERONE USP28;Halotestin;Fluoxymesterone (JAN/USP/INN);Ora Testryl;Androst-4-en-3-one, 9-fluoro-11,17-dihydroxy-17-methyl-, (11beta,17beta)-;9-Fluoro-11-beta,17-beta-dihydroxy-17-methylandrost-4-en-3-one;Q410663;DTXSID8033512;Fluoxymesterone, solid (photosensitive);9alpha-Fluoro-11beta,17beta-dihydroxy-17-methylandrost-4-en-3-one;FLUOXYMESTERONE [MI];(11-beta,17-beta)-9-Fluoro-11,17-dihydroxy-17-methylandrost-4-en-3-one;9-Fluoro-11beta,17beta-dihydroxy-17-methylandrost-4-en-3-one;9-alpha-Fluoro-11-beta,17-beta-dihydroxy-17-alpha-methyl-4-androstene-3-one;9.alpha.-Fluoro-11.beta.,17.beta.-dihydroxy-17.alpha.-methyl-4-androstene-3-one;9-alpha-Fluoro-11-beta-hydroxy-17-methyltestosterone;Fluotestin;9JU12S4YFY;Fluoxymesteronum [INN-Latin];Fluosterone;FXM;Flusteron;(11beta,17beta)-9-fluoro-11,17-dihydroxy-17-methylandrost-4-en-3-one;W-104363;FLUOXYMESTERONE [MART.];GTPL2861;DTXCID6013512;FLUOXYMESTERONE [JAN];Oratestin;NSC12165;Neo-Ormonal;NCGC00258408-01;AI3-52940;LS-19496;Androst-4-en-3-one, 9-fluoro-11beta,17beta-dihydroxy-17-methyl-;Fluoxymestrone;Androxy (TN);9-alpha-Fluoro-17-alpha-methyl-11-beta,17-dihydroxy-4-androsten-3-one;Tox21_113158;NCGC00091037-02;FLUOXYMESTERONE [WHO-DD];CCRIS 9036;4-08-00-02057 (Beilstein Handbook Reference);Fluoximesteronum;17-alpha-Methyl-9-alpha-fluoro-11-beta-hydroxytesterone;SMR000686158;D00327;Androxy;Androst-4-en-3-one, 9-fluoro-11beta,17beta-dihydroxy-17-methyl-(VAN) (8CI);NSC-12165;FLUOXYMESTERONE [VANDF];Fluoxymesteronum;Fluoxymesterone [INN:BAN:JAN];BDBM18189;NCGC00091037-01;Ultandren;11-beta,17-beta-Dihydroxy-9-alpha-fluoro-17-alpha-methyl-4-androster-3-one;Fluoxymesterone (JP15/USP/INN);Fluoxymesterone 1.0 mg/ml in Acetonitrile;9alpha-Fluoro-11beta,17beta-dihydroxy-17alpha-methyl-4-androstene-3-one;9alpha-Fluoro-11beta-hydroxy-17-methyltestosterone;MLS001055414;Fluoro-9-alpha dihydroxy-11-beta,17-beta methyl-17-alpha androstene-4 one-3;DB01185;CHEBI:5120;AC-29744;NSC 10704;Fluoxymesterone [BAN:INN:JAN];C20H29FO3;SCHEMBL5096;Androst-4-en-3-one, 9-fluoro-11beta,17beta-dihydroxy-17-methyl- (VAN);NSC10704;76-43-7;AKOS015895109;Androst-4-en-3-one, 9-fluoro-11beta,17beta-dihydroxy-17-methyl-(VAN);(8S,9R,10S,11S,13S,14S,17S)-9-fluoranyl-10,13,17-trimethyl-11,17-bis(oxidanyl)-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one;Fluoxymesterone ciii;fluoxymesteron-;Tox21_200854;Ora-Testryl;11beta,17beta-Dihydroxy-9alpha-fluoro-17alpha-methyl-4-androster-3-one;D0L2LS;component of Halodrin;Androfluorene;Halotestin (TN);BCP10776;FLUOXYMESTERONE [USP MONOGRAPH];Fluoximesterona [INN-Spanish];17alpha-Methyl-9alpha-fluoro-11beta-hydroxytesterone;Ultandrene;Testosterone, 9-fluoro-11.beta.-hydroxy-17-methyl-;Androsterolo;HMS2272B06;Androst-4-en-3-one, 9-fluoro-11,17-dihydroxy-17-methyl-, (11.beta.,17.beta.)-;FLUOXYMESTERONE [INN];U 6040;Androst-4-en-3-one, 9-fluoro-11-beta,17-beta-dihydroxy-17-methyl-;11-beta,17-beta-dihydroxy-9-alpha-fluoro-17-alpha-methyl-4-androsten-3-one;(1R,2S,10S,11S,14S,15S,17S)-1-fluoro-14,17-dihydroxy-2,14,15-trimethyltetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadec-6-en-5-one;Fluossimesterone;9alpha-Fluoro-11beta,17beta-dihydroxy-17alpha-methylandrost-4-en-3-one;Fluoximesteron;FLUOXYMESTERONE [ORANGE BOOK];A838701;CHEMBL1445;EINECS 200-961-8;11beta,17beta-Dihydroxy-9alpha-fluoro-17alpha-methyl-4-androsten-3-one;NSC-10704;Fluoxymesteron;9-fluoro-11beta,17beta-dihydroxy-17alpha-methylandrost-4-en-3-one;Fluoximesterone;Testosterone, 9-fluoro-11beta-hydroxy-17-methyl-;Android-f;FLUOXYMESTERONE CIII [USP-RS];Androfluorone;9alpha-Fluoro-17alpha-methyl-11beta,17-dihydroxy-4-androsten-3-one;Flutestos;CAS-76-43-7;Testoral;Fluoximesterona;NCGC00182970-01;LMST02020025;HSDB 3333;UNII-9JU12S4YFY;Fluoxymesterone [USP:INN:BAN:JAN];9.alpha.-Fluoro-11.beta.-hydroxy-17-methyltestosterone;FLUOXYMESTERONE [HSDB];CS-O-01553;BRN 2008796;(8S,9R,10S,11S,13S,14S,17S)-9-fluoro-11,17-dihydroxy-10,13,17-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one;Fluossimesterone [DCIT];Oralsterone;Anadroid-F;9alpha-Fluoro-11beta-hydroxy-17alpha-methyltestosterone;Fluoxymesterone, 1mg/ml in Acetonitrile;Fluoro-9-alpha dihydroxy-11-beta,17-beta methyl-17-alpha androstene-4 one-3 [French];FLUOXYMESTERONE (MART.);Fluoxymesterone (1mg/ml in 1,2-Dimethoxyethane);FLUOXYMESTERONE CIII (USP-RS);Fluoxymesteronum (INN-Latin);Halodrin;Fluoxymesterone (1mg/ml in Acetonitrile);Fluoxymesterone (USP:INN:BAN:JAN);Fluoxymesterone (1.0 mg/ml in Methanol);Fluoximesterona (INN-Spanish);FLUOXYMESTERONE (USP MONOGRAPH);G03BA01;YLRFCQOZQXIBAB-RBZZARIASA-N;BRD-K24255045-001-05-3;200-961-8;

标识符

MDL:
F194963
InChIKey:
YLRFCQOZQXIBAB-RBZZARIASA-N
Inchi:
1S/C20H29FO3/c1-17-8-6-13(22)10-12(17)4-5-15-14-7-9-19(3,24)18(14,2)11-16(23)20(15,17)21/h10,14-16,23-24H,4-9,11H2,1-3H3/t14-,15-,16-,17-,18-,19-,20-/m0/s1
SMILES:
F[C@]12[C@H](C[C@]3(C)[C@](C)(CC[C@H]3[C@@H]1CCC1=CC(CC[C@]21C)=O)O)O

氟甲睾酮(76-43-7)物化性质

实验特性

  • LogP : 3.33220
  • PSA : 57.53000
  • Merck : 13,4212
  • 折射率 : 1.562
  • 水溶性 : 可忽略
  • 沸点 : 474.2 °C at 760 mmHg
  • 熔点 : 240 ºC
  • 闪点 : 240.6 °C
  • 溶解度 : H2O: ≤0.5 mg/mL
  • 颜色与性状 : 白色无味粉末
  • 溶解性 : 微溶于水
  • 比旋光度 : 104 º (c=1,EtOH)
  • 密度 : 1.0455 (estimate)

计算特性

  • 精确分子量 : 336.21000
  • 氢键供体数量 : 2
  • 氢键受体数量 : 3
  • 可旋转化学键数量 : 0
  • 同位素质量 : 336.210073
  • 重原子数量 : 24
  • 复杂度 : 630
  • 同位素原子数量 : 0
  • 确定原子立构中心数量 : 7
  • 不确定原子立构中心数量 : 0
  • 确定化学键立构中心数量 : 0
  • 不确定化学键立构中心数量 : 0
  • 共价键单元数量 : 1
  • 疏水参数计算参考值(XlogP) : 无
  • 互变异构体数量 : 5
  • 表面电荷 : 0
  • 拓扑分子极性表面积 : 57.5

氟甲睾酮(76-43-7)国际标准相关数据

EINECS:
200-961-8

氟甲睾酮(76-43-7)海关数据

海关编码:
2937290018
海关数据:

中国海关编码:

2937290018

氟甲睾酮(76-43-7)生产方法和用途

用途:
生化研究

氟甲睾酮(76-43-7)推荐厂家 更多厂家(29)

公司名称手机号/电话联系人QQ微信询单
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JACS-郑州杰克斯化工产品有限公司 15981966935
0371-86259281
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湖北实兴化工有限公司 13554155445
13554155445
张妍 1273554433
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0512-83500002
陈小姐询单
上海源溪生物科技有限公司 13564518121李经理 1724405207 询单

氟甲睾酮(76-43-7)参考资料

Beilstein:
F194963
PubChem CID:

氟甲睾酮(76-43-7) MSDS

基础信息

Name:Fluoxymesterone 97.0-102.0% hplc (on dry substance) Material Safety Data Sheet
Synonym:(11beta,17beta)-9-Fluoro-11,17-dihydroxy-17-methylandrost-4-en-3-on
CAS:76-43-7
Section 1 - Chemical Product ? MSDS Name:Fluoxymesterone 97.0-102.0% hplc (on dry substance) Material Safety Data Sheet
Synonym:(11beta,17beta)-9-Fluoro-11,17-dihydroxy-17-methylandrost-4-en-3-on

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS#Chemical NamecontentEINECS#
76-43-7FLUOXYMESTERONE97.0-102200-961-8
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
? EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
Prolonged or repeated exposure may cause adverse reproductive effects.

Section 4 - FIRST AID MEASURES
? Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
? General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
? General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions.

Section 7 - HANDLING and STORAGE
? Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.
Hormones and antibiotics room.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
? Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 76-43-7: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
?
Physical State: Solid
Color: white
Odor: Odorless
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 240 deg C dec
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: negligible
Specific Gravity/Density:
Molecular Formula: C20H29FO3
Molecular Weight: 336.45

Section 10 - STABILITY AND REACTIVITY
? Chemical Stability:
Stable.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, hydrogen fluoride gas.
Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION
? RTECS#:
CAS# 76-43-7: BV8390000 LD50/LC50:
Not available.
Carcinogenicity:
FLUOXYMESTERONE - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
?

Section 13 - DISPOSAL CONSIDERATIONS
? Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
?
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION
?
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 76-43-7: No information available.
Canada
CAS# 76-43-7 is listed on Canada's DSL List.
CAS# 76-43-7 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 76-43-7 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A