824-46-4 (甲氧基对苯二酚,2-Methoxybenzene-1,4-diol)

反应条件：

1.1 Reagents: Chlorotrimethylsilane , 1,1,3,3-Tetramethyldisiloxane , Sodium iodide Solvents: Dichloromethane

参考文献：

Ionic and organometallic-catalyzed organosilane reductions

Larson, Gerald L.; et al, Organic Reactions (Hoboken, 2008, 71, 1-737

合成路线：1 步

2880-58-2

_98%

反应条件：

1.1 Reagents: Chlorotrimethylsilane , 1,1,3,3-Tetramethyldisiloxane , Sodium iodide Solvents: Acetonitrile , Dichloromethane

参考文献：

Reagents and synthetic methods. 57. Reduction of carbonyl compounds promoted by silicon hydrides under the influence of trimethylsilyl-based reagents

Aizpurua, Jesus M.; et al, Canadian Journal of Chemistry, 1986, 64(12), 2342-7

合成路线：1 步

2880-58-2

反应条件：

1.1 Reagents: Sodium dithionite Solvents: Water ; 0.5 - 1 h, rt

参考文献：

Selective activation of C-H bond into C=O bond of phenols in para-position via aerobic oxidation

Yang, Shilei; et al, Catalysis Communications, 2019, 123, 105-108

合成路线：1 步

_97%

反应条件：

1.1 Reagents: Sodium percarbonate Solvents: Tetrahydrofuran , Water ; overnight, 25 °C
1.2 Reagents: Hydrochloric acid Solvents: Water ; pH 1, 25 °C

参考文献：

Epoxy thermosets from model mixtures of the lignin-to-vanillin process

Fache, M.; et al, Green Chemistry, 2016, 18(3), 712-725

合成路线：1 步

_97%

反应条件：

1.1 Reagents: Sodium carbonate , Hydrogen peroxide Solvents: Water ; rt

参考文献：

Amine hardeners and epoxy cross-linker from aromatic renewable resources

Fache, Maxence; et al, European Polymer Journal, 2015, 73, 344-362

合成路线：1 步

_97%

反应条件：

1.1 Reagents: Sodium carbonate Solvents: Tetrahydrofuran , Water ; rt; 3 h, rt
1.2 Reagents: Hydrochloric acid Solvents: Water ; pH 3

参考文献：

New vanillin-derived diepoxy monomers for the synthesis of biobased thermosets

Fache, Maxence; et al, European Polymer Journal, 2015, 67, 527-538

合成路线：1 步

498-02-2

_91%

反应条件：

1.1 Reagents: Sodium percarbonate Solvents: Tetrahydrofuran , Water ; overnight, 25 °C
1.2 Reagents: Hydrochloric acid Solvents: Water ; pH 1, 25 °C

参考文献：

Epoxy thermosets from model mixtures of the lignin-to-vanillin process

Fache, M.; et al, Green Chemistry, 2016, 18(3), 712-725

合成路线：1 步

139209-92-0

_58%

反应条件：

1.1 Reagents: Butyllithium , N,N,N′,N′-Tetramethylethylenediamine

参考文献：

The generation of C,O,O-trilithiated derivatives of dihydric phenols

Saa, Jose M.; et al, Tetrahedron Letters, 1991, 32(49), 7313-16

合成路线：1 步

_40%

参考文献：

Oxidative decarbonylation of phenolic acids by singlet oxygen

Chibber, S. S.; et al, Indian Journal of Chemistry, 1982, (4), 352-3

合成路线：1 步

参考文献：

Vanillic acid metabolism by Sporotrichum pulverulentum: evidence for demethoxylation before ring cleavage

Ander, Paul; et al, Archives of Microbiology, 1983, 136(1), 1-6

合成路线：1 步

参考文献：

Vanillate hydroxylase from the white rot basidiomycete Phanerochaete chrysosporium

Yajima, Yasuo; et al, Archives of Microbiology, 1979, 123(3), 319-21

合成路线：1 步

61654-67-9

_28%

反应条件：

1.1 Reagents: Butyllithium , N,N,N′,N′-Tetramethylethylenediamine

参考文献：

The generation of C,O,O-trilithiated derivatives of dihydric phenols

Saa, Jose M.; et al, Tetrahedron Letters, 1991, 32(49), 7313-16

合成路线：1 步

1135-24-6

参考文献：

Metabolism of trans-ferulic acid by the white-rot fungus Sporotrichum pulverulentum

Grupta, Jugal K.; et al, Archives of Microbiology, 1981, 128(4), 349-54

合成路线：1 步

150-19-6

反应条件：

1.1 Solvents: Dimethylformamide , Water ; 60 min, pH 6.5, 37 °C

参考文献：

Saturation mutagenesis of Burkholderia cepacia R34 2,4-dinitrotoluene dioxygenase at DntAc valine 350 for synthesizing nitrohydroquinone, methylhydroquinone, and methoxyhydroquinone

Keenan, Brendan G.; et al, Applied and Environmental Microbiology, 2004, 70(6), 3222-3231

合成路线：1 步

537-98-4

参考文献：

Vanillin as a product of ferulic acid biotransformation by the white-rot fungus Pycnoporus cinnabarinus I-937: Identification of metabolic pathways

Falconnier, B.; et al, Journal of Biotechnology, 1994, 37(2), 123-32

合成路线：1 步

73759-43-0

反应条件：

1.1 Reagents: (T-4)-Chlorodioxo(1,1,1-trimethylsilanolato)chromium Solvents: Dichloromethane

参考文献：

Reagents and synthetic methods. 45. Synthetic applications of chromium(VI) reagents in combination with chlorotrimethylsilane

Cossio, Fernando P.; et al, Canadian Journal of Chemistry, 1986, 64(2), 225-31

合成路线：1 步

78018-54-9

反应条件：

1.1 Reagents: (T-4)-Chlorodioxo(1,1,1-trimethylsilanolato)chromium Solvents: Dichloromethane

参考文献：

Reagents and synthetic methods. 45. Synthetic applications of chromium(VI) reagents in combination with chlorotrimethylsilane

Cossio, Fernando P.; et al, Canadian Journal of Chemistry, 1986, 64(2), 225-31

合成路线：1 步

90-05-1

反应条件：

1.1 Solvents: Dimethylformamide , Water ; 60 min, pH 6.5, 37 °C

参考文献：

Saturation mutagenesis of Burkholderia cepacia R34 2,4-dinitrotoluene dioxygenase at DntAc valine 350 for synthesizing nitrohydroquinone, methylhydroquinone, and methoxyhydroquinone

Keenan, Brendan G.; et al, Applied and Environmental Microbiology, 2004, 70(6), 3222-3231

合成路线：2 步

90-05-1

反应条件：

1.1 Reagents: Oxygen Catalysts: Cuprous chloride Solvents: Acetonitrile , Water ; 3 h, 2 MPa, 50 °C
2.1 Reagents: Sodium dithionite Solvents: Water ; 0.5 - 1 h, rt

参考文献：

Selective activation of C-H bond into C=O bond of phenols in para-position via aerobic oxidation

Yang, Shilei; et al, Catalysis Communications, 2019, 123, 105-108

合成路线：2 步

9005-53-2

反应条件：

1.1 -
2.1 Reagents: Sodium percarbonate Solvents: Tetrahydrofuran , Water ; overnight, 25 °C
2.2 Reagents: Hydrochloric acid Solvents: Water ; pH 1, 25 °C

参考文献：

Epoxy thermosets from model mixtures of the lignin-to-vanillin process

Fache, M.; et al, Green Chemistry, 2016, 18(3), 712-725

合成路线：1 步

1135-24-6

_88%

反应条件：

1.1 Reagents: Maltose , Diammonium tartrate Solvents: Water ; 7 d, 30 °C

参考文献：

A two-step bioconversion process for vanillin production from ferulic acid combining Aspergillus niger and Pycnoporus cinnabarinus

Lesage-Meessen, Laurence; et al, Journal of Biotechnology, 1996, 50, 107-113

合成路线：1 步

_22%

反应条件：

1.1 Reagents: Maltose , Diammonium tartrate Solvents: Water ; 7 d, 30 °C

参考文献：

A two-step bioconversion process for vanillin production from ferulic acid combining Aspergillus niger and Pycnoporus cinnabarinus

Lesage-Meessen, Laurence; et al, Journal of Biotechnology, 1996, 50, 107-113

合成路线：1 步

498-02-2

57244-88-9

反应条件：

1.1 Reagents: Acetic acid , Peracetic acid Solvents: Water ; 1 h, pH 3, 60 °C

参考文献：

The Baeyer-Villiger oxidation of ketones and aldehydes

Krow, Grant R., Organic Reactions (Hoboken, 1993, 43,

合成路线：1 步

90-05-1

6100-60-3

反应条件：

1.1 Catalysts: Toluene monooxygenase

参考文献：

Alanine 101 and alanine 110 of the alpha subunit of Pseudomonas stutzeri OX1 toluene-o-xylene monooxygenase influence the regiospecific oxidation of aromatics

Vardar, Gonul; et al, Biotechnology and Bioengineering, 2005, 92(5), 652-658

合成路线：2 步

1135-24-6