826-74-4 (1-乙烯萘酯,1-Vinylnaphthalene Stabilized with 4000ppm tert-Butylcatechol)

反应条件：

1.1 Reagents: Potassium hydroxide Solvents: Tetrahydrofuran ; 1 h, 100 °C; 100 °C → rt
1.2 Catalysts: Triphenylphosphine , Palladium diacetate Solvents: Methanol ; 1 h, 100 °C; 100 °C → rt

参考文献：

Simple and Efficient Protocol for the Synthesis of Functionalized Styrenes from 1,2-Dibromoethane and Arylboronic Acids

Lando, Vanusa R.; et al, Organic Letters, 2003, 5(16), 2891-2894

合成路线：1 步

15727-65-8

_100%

反应条件：

1.1 Reagents: Hydrogen Catalysts: Iron oxide (inorganic oxide supported) Solvents: Mesitylene ; 20 h, 10 bar, 100 °C

参考文献：

Synthesis of Supported Planar Iron Oxide Nanoparticles and Their Chemo- and Stereoselectivity for Hydrogenation of Alkynes

Tejeda-Serrano, Maria; et al, ACS Catalysis, 2017, 7(5), 3721-3729

合成路线：1 步

1779-49-3

_100%

反应条件：

1.1 Reagents: Potassium tert-butoxide Solvents: Toluene ; 30 min, 0 °C; 4 h, rt; rt → 0 °C
1.2 overnight, rt

参考文献：

Novel cyclization cascades to functionalized indanes and tetrahydronaphthalenes

Khan, Zulfiqar A.; et al, Tetrahedron, 2010, 66(33), 6639-6646

合成路线：1 步

1779-49-3

_100%

反应条件：

1.1 Reagents: Potassium tert-butoxide Solvents: Toluene ; 30 min, 0 °C; 4 h, rt
1.2 overnight, rt

参考文献：

Diselenide- and Disulfide-Mediated Synthesis of Isocoumarins

Shahzad, Sohail A.; et al, European Journal of Organic Chemistry, 2010, (18), 3465-3472

合成路线：1 步

1779-49-3

_100%

反应条件：

1.1 Reagents: Potassium tert-butoxide Solvents: Toluene ; 30 min, 0 °C; 4 h, rt; rt → 0 °C
1.2 overnight, rt

参考文献：

Selenium-Mediated Synthesis of Biaryls through Rearrangement

Shahzad, Sohail A.; et al, Organic Letters, 2010, 12(6), 1364-1367

合成路线：1 步

773-99-9

_100%

参考文献：

Reactions with nitrosodisulfonate. XX. Chrysene-3,6-quinone and dinaphthoanthraquinone

Teuber, Hans Joachim; et al, Chemische Berichte, 1959, 92, 921-6

合成路线：2 步

773-99-9

反应条件：

1.1 Reagents: Thionyl chloride
2.1 Catalysts: Potassium tert-butoxide

参考文献：

A practical large-scale synthesis of (1-naphthyl)acetylene

Hanekamp, Jaap C.; et al, Synthetic Communications, 1989, 19(15), 2677-82

合成路线：1 步

121825-35-2

_99%

反应条件：

1.1 Catalysts: 1637333-83-5 Solvents: Tetrahydrofuran ; 5 h, 50 °C

参考文献：

Synthesis, mechanism of formation, and catalytic activity of Xantphos nickel π-complexes

Staudaher, Nicholas D.; et al, Chemical Communications (Cambridge, 2014, 50(98), 15577-15580

合成路线：1 步

63918-53-6

13922-41-3

_99%

反应条件：

1.1 Reagents: Potassium carbonate Catalysts: Disodium tetrachloropalladate , 9H-Fluorene-2-sulfonic acid, 9-(dicyclohexylphosphino)-9-[3-(4-sulfophenyl)propy… Solvents: Water ; 3 h, 45 °C
1.2 Reagents: Potassium carbonate Solvents: Water ; 16 h, 95 °C

参考文献：

Retracted Article: Cross coupling in water: Suzuki-Miyaura vinylation and difluorovinylation of arylboronic acids

Pschierer, Jan; et al, Green Chemistry, 2010, 12(4), 636-642

合成路线：1 步

83813-73-4

13922-41-3

_99%

反应条件：

参考文献：

Retracted Article: Cross coupling in water: Suzuki-Miyaura vinylation and difluorovinylation of arylboronic acids

Pschierer, Jan; et al, Green Chemistry, 2010, 12(4), 636-642

合成路线：1 步

1517-72-2

_97%

反应条件：

1.1 Reagents: Oxalyl chloride Solvents: Dimethylformamide ; 0 °C; 52 h, 95 °C

参考文献：

"Conducted Tour" Migration of Li+ during the cis/trans Stereoinversion of α-Arylvinyllithiums

Knorr, Rudolf; et al, Chemistry - A European Journal, 2017, 23(52), 12861-12869

合成路线：1 步

1517-72-2

_68%

反应条件：

1.1 Reagents: Alumina

参考文献：

The kinetics of polymerization of 1-vinylnaphthalene

Loshaek, S.; et al, Journal of Polymer Science, 1959, 39, 223-39

合成路线：1 步

2768-02-7

_98%

反应条件：

1.1 Reagents: Tetrabutylammonium bromide Catalysts: Di-μ-chlorobis[5-hydroxy-2-[1-(hydroxyimino-κN)ethyl]phenyl-κC]dipalladium Solvents: Water ; 5 min, rt
1.2 Reagents: Sodium hydroxide Solvents: Water ; rt; rt → 120 °C; 24 h, 120 °C; 120 °C → rt

参考文献：

The first fluoride-free Hiyama reaction of vinylsiloxanes promoted by sodium hydroxide in water

Alacid, Emilio; et al, Advanced Synthesis & Catalysis, 2006, 348(15), 2085-2091

合成路线：1 步

2768-02-7

_92%

反应条件：

1.1 Reagents: Sodium hydroxide , Tetrabutylammonium bromide Catalysts: Di-μ-chlorobis[5-hydroxy-2-[1-(hydroxyimino-κN)ethyl]phenyl-κC]dipalladium Solvents: Water ; 20 min, 120 °C

参考文献：

Aqueous Sodium Hydroxide Promoted Cross-Coupling Reactions of Alkenyltrialkoxysilanes under Ligand-Free Conditions

Alacid, Emilio; et al, Journal of Organic Chemistry, 2008, 73(6), 2315-2322

合成路线：1 步

369404-32-0

_98%

反应条件：

1.1 Catalysts: Dichlorobis(triphenylphosphine)palladium Solvents: Tetrahydrofuran ; 12 h, 60 °C

参考文献：

Pd-catalyzed cross-coupling of haloarenes and chloroarene-Cr(CO)3 complexes with stabilized vinyl- and allylaluminium reagents

Schumann, Herbert; et al, Synlett, 2003, (12), 1783-1788

合成路线：1 步

754-05-2

_98%

反应条件：

1.1 Reagents: Triethyl phosphite , Sulfiliminium, S,S-bis(diethylamino)-N,N-diethyl-, difluorotrimethylsilicate(1-)… Catalysts: Di-μ-chlorobis(η3-2-propenyl)dipalladium Solvents: Hexamethylphosphoramide

参考文献：

Cross-coupling of organosilanes with organic halides mediated by a palladium catalyst and tris(diethylamino)sulfonium difluorotrimethylsilicate

Hatanaka, Yasuo; et al, Journal of Organic Chemistry, 1988, 53(4), 918-20

合成路线：1 步

754-05-2

_86%

反应条件：

1.1 Reagents: Tetrabutylammonium chloride , Potassium fluoride Catalysts: Bis(dibenzylideneacetone)palladium Solvents: Toluene

参考文献：

Tetraalkylammonium salt-based catalyst systems for directing the arylation of vinyltrimethylsilane

Jeffery, Tuyet, Tetrahedron Letters, 1999, 40(9), 1673-1676

合成路线：1 步

754-05-2

_55%

反应条件：

1.1 Catalysts: Di-μ-chlorobis(η3-2-propenyl)dipalladium Solvents: Dimethylformamide

参考文献：

The electrophilic substitution of allylsilanes and vinylsilanes

Fleming, Ian; et al, Organic Reactions (Hoboken, 1989, 37,

合成路线：1 步

77295-63-7

_97%

反应条件：

1.1 Reagents: Samarium Solvents: Methanol ; 6 h, 45 °C

参考文献：

Unexpected chemoselective debromination and reduction of 1,1-dibromo-1-alkenes mediated by samarium metal in methanol

Wang, Lei; et al, Synlett, 2003, (8), 1137-1140

合成路线：1 步

1643415-52-4

_96%

反应条件：

1.1 Solvents: Tetrahydrofuran ; 3 h, 25 °C

参考文献：

Isolation and Structural Characterization of Geminal Di(iodozincio)methane Complexes Stabilized with Nitrogen Ligands

Nishida, Yusuke; et al, Journal of the American Chemical Society, 2015, 137(1), 114-117

合成路线：1 步

4627-10-5

_96%

反应条件：

1.1 Reagents: Silver oxide (Ag2O) Catalysts: Tetrakis(triphenylphosphine)palladium Solvents: Tetrahydrofuran ; 24 h, 67 °C

参考文献：

4,4,6-Trimethyl-2-vinyl-1,3,2-dioxaborinane: an efficient and selective 2-carbon building block for vinylboronate Suzuki-Miyaura coupling reactions

Lightfoot, Andrew P.; et al, Synlett, 2005, (3), 529-531

合成路线：1 步

_96%

反应条件：

1.1 Catalysts: Tetrakis(triphenylphosphine)palladium Solvents: Tetrahydrofuran ; 60 °C
1.2 Reagents: Sodium bicarbonate Solvents: Water

参考文献：

Tetraorganoindates as Nucleophilic Coupling Partners in Pd-Catalyzed Cross-Coupling Reactions

Lee, Phil Ho; et al, Organic Letters, 2003, 5(26), 4963-4966

合成路线：1 步

2768-02-7

_94%

反应条件：

1.1 Reagents: Sodium hydroxide , Tetrabutylammonium bromide Catalysts: Di-μ-chlorobis[5-hydroxy-2-[1-(hydroxyimino-κN)ethyl]phenyl-κC]dipalladium Solvents: Water ; 10 min, 120 °C

参考文献：

Aqueous Sodium Hydroxide Promoted Cross-Coupling Reactions of Alkenyltrialkoxysilanes under Ligand-Free Conditions

Alacid, Emilio; et al, Journal of Organic Chemistry, 2008, 73(6), 2315-2322

合成路线：1 步

4780-79-4

67-71-0

_94%

反应条件：

1.1 Reagents: Potassium tert-butoxide Catalysts: Platinum Solvents: Toluene ; 15 h, reflux

参考文献：

Direct Olefination of Alcohols with Sulfones by Using Heterogeneous Platinum Catalysts

Siddiki, S. M. A. Hakim; et al, Chemistry - A European Journal, 2016, 22(17), 6111-6119

合成路线：1 步

4780-79-4

67-71-0

_68%

反应条件：

1.1 Reagents: Potassium tert-butoxide Catalysts: 1,10-Phenanthroline , Ferrous chloride Solvents: Toluene ; 8 h, 120 °C

参考文献：

Iron-Catalyzed Direct Julia-Type Olefination of Alcohols

Landge, Vinod G.; et al, Journal of Organic Chemistry, 2020, 85(15), 9876-9886

合成路线：1 步

4780-79-4

67-71-0

_50%

反应条件：

1.1 Reagents: Potassium tert-butoxide Catalysts: Ruthenium, carbonylchloro[6-[(diphenylphosphino-κP)methyl]-2,2′-bipyridine-κN1,κ… Solvents: 1,4-Dioxane ; 5 h, 125 °C

参考文献：

Direct Catalytic Olefination of Alcohols with Sulfones

Srimani, Dipankar; et al, Angewandte Chemie, 2014, 53(41), 11092-11095

合成路线：1 步

_94%

反应条件：

1.1 Catalysts: Tri-tert-butylphosphine , Tris(dibenzylideneacetone)dipalladium Solvents: Toluene

参考文献：

Pd/P(t-Bu)3: A Mild and General Catalyst for Stille Reactions of Aryl Chlorides and Aryl Bromides

Littke, Adam F.; et al, Journal of the American Chemical Society, 2002, 124(22), 6343-6348

合成路线：1 步

参考文献：

Product class 3: bromoarenes

Stanforth, S. P., Science of Synthesis, 2007, 31, 121-160

合成路线：1 步

13682-77-4

90-13-1

_93%

反应条件：

1.1 Reagents: Cesium carbonate Catalysts: (-)-BINAP , Di-μ-chlorobis[5-hydroxy-2-[1-(hydroxyimino-κN)ethyl]phenyl-κC]dipalladium Solvents: Dimethylformamide ; 20 h, 120 °C; 120 °C → rt

参考文献：

General Reaction Conditions for the Palladium-Catalyzed Vinylation of Aryl Chlorides with Potassium Alkenyltrifluoroborates

Alacid, Emilio; et al, Journal of Organic Chemistry, 2009, 74(21), 8191-8195

合成路线：1 步

133042-64-5

_92%

反应条件：

1.1 Reagents: Lithium chloride Catalysts: Dichlorobis(triphenylphosphine)palladium Solvents: Dimethylformamide

参考文献：

The Stille reaction

Farina, Vittorio; et al, Organic Reactions (Hoboken, 1997, 50,

合成路线：1 步

133042-64-5

_92%