830-81-9 (乙酸-1-萘酯,1-Naphthyl acetate)

_100%

反应条件：

1.1 Reagents: Triethylamine Catalysts: 4-(Dimethylamino)pyridine Solvents: Dichloromethane ; 1 h, rt
1.2 Reagents: Hydrochloric acid Solvents: Water

参考文献：

Novel naphthyl based 1,2,4-trioxanes: Synthesis and in-vivo efficacy in the Plasmodium yoelii nigeriensis in Swiss mice

Karnatak, Manvika; et al, Bioorganic & Medicinal Chemistry Letters, 2021, 51,

合成路线：1 步

_100%

反应条件：

1.1 Catalysts: 1-Butanaminium, N,N,N-tributyl-, (dichlorostannate)octatetraconta-μ-oxotetra-μ6-… Solvents: Acetonitrile ; 6 min, rt

参考文献：

New porphyrin-polyoxometalate hybrid materials: synthesis, characterization and investigation of catalytic activity in acetylation reactions

Araghi, Mehdi; et al, Dalton Transactions, 2012, 41(38), 11745-11752

合成路线：1 步

_100%

反应条件：

1.1 Catalysts: (OC-6-12)-[[4,4′,4′′,4′′′-(21H,23H-Porphine-5,10,15,20-tetrayl-κN21,κN22,κN23,κN… (supported on chloromethylated polystyrene) Solvents: Acetonitrile ; 8 min, rt

参考文献：

Polystyrene-bound electron-deficient tin(IV) porphyrin: A new, highly efficient, robust and reusable catalyst for acetylation of alcohols and phenols with acetic anhydride

Moghadam, Majid; et al, Comptes Rendus Chimie, 2011, 14(12), 1080-1087

合成路线：1 步

_100%

反应条件：

1.1 Catalysts: Titania ; 25 min, 25 °C

参考文献：

TiO2, a simple and an efficient catalyst for esterification of phenols under solvent-free condition

Pasha, Mohamed Afzal; et al, Indian Journal of Chemistry, 2008, (4), 597-600

合成路线：1 步

_99%

反应条件：

1.1 Reagents: Pyridine Solvents: Dichloromethane ; 0 °C → rt; 3 h, rt

参考文献：

NIS/TBHP Induced Regioselective Selenation of (Hetero)Arenes via Direct C-H Functionalization

Ding, Chaochao; et al, ChemCatChem, 2018, 10(23), 5397-5401

合成路线：1 步

_99%

反应条件：

1.1 Catalysts: Cobalt chloride (CoCl2) ; 15 s, rt

参考文献：

Highly efficient cobalt (II) catalyzed O-acylation of alcohols and phenols under solvent-free conditions

Mulla, Shafeek A. R.; et al, Open Journal of Synthesis Theory and Applications, 2012, 1(3), 31-35

合成路线：1 步

_98%

反应条件：

1.1 Catalysts: 2,2′:6′,2′′-Terpyridine , Cobalt(II) acetylacetonate Solvents: Dimethyl sulfoxide ; 5 bar, rt; 18 h, 5 bar, 120 °C

参考文献：

Cobalt-catalyzed carbonylative acetylation of phenols

An, Da-Lie; et al, Journal of Catalysis, 2023, 421, 194-197

合成路线：1 步

127-09-3

_95%

反应条件：

1.1 Reagents: (Diethylamino)sulfur trifluoride Catalysts: 4-(Dimethylamino)pyridine Solvents: Acetonitrile ; rt; 6 h, rt

参考文献：

Acylation of phenols to phenolic esters with organic salts

Zhang, Zhanrong; et al, Green Chemistry, 2022, 24(24), 9763-9771

合成路线：1 步

3019-88-3

_94%

反应条件：

1.1 Solvents: Acetonitrile ; rt; 5 - 15 min, rt

参考文献：

Synthesis and antibacterial activity of 1-naphthyl ethers and esters

Pawar Nilesh, S.; et al, Research Journal of Chemistry and Environment, 2013, 17(2), 25-29

合成路线：1 步

6202-48-8

_92%

反应条件：

1.1 Catalysts: Bismuth triflate Solvents: Acetonitrile

参考文献：

Efficient and selective conversion of trimethylsilyl and tetrahydropyranyl ethers to their corresponding acetates and benzoates catalyzed by bismuth(III) salts

Mohammadpoor-Baltork, Iraj; et al, Monatshefte fuer Chemie, 2002, 133(2), 189-193

合成路线：1 步

6202-48-8

_82%

反应条件：

1.1 Catalysts: Sulfuric acid (silica-bound) Solvents: Dichloromethane ; 60 min, rt

参考文献：

An efficient and convenient method for desilylation-acetylation of trimethylsilyl ethers catalyzed by silica sulfuric acid

Jin, Tong-Shou; et al, Asian Journal of Chemistry, 2008, 20(7), 5005-5010

合成路线：1 步

6202-48-8

_78%

反应条件：

1.1 Catalysts: Titania , Sulfate Solvents: Acetic anhydride ; 35 min, rt

参考文献：

TiO2/SO42-, a convenient and efficient catalyst for desilylation-acetylation of trimethylsilyl ethers with acetic anhydride

Jin, Tong-Shou; et al, Journal of Chemical Research, 2003, (2), 98-100

合成路线：1 步

17545-30-1

_91%

反应条件：

1.1 Solvents: Acetic anhydride , 1,4-Dioxane

参考文献：

Acetylation of polymer supported phenoxides by acetic anhydride in nonaqueous medium

Ram, B.; et al, Indian Journal of Chemistry, 1988, (7),

合成路线：1 步

607-58-9

506-96-7

_70%

反应条件：

1.1 Reagents: Lithium bromide Solvents: Dichloromethane ; 24 h, 30 - 35 °C

参考文献：

Counterattack Mode Differential Acetylative Deprotection of Phenylmethyl Ethers: Applications to Solid Phase Organic Reactions

Chakraborti, Asit K.; et al, Journal of Organic Chemistry, 2009, 74(3), 1367-1370

合成路线：1 步

575-36-0

_91%

反应条件：

1.1 Reagents: Sodium nitrite Solvents: Acetic acid , Acetic anhydride
1.2 Reagents: Water

参考文献：

Conversion of N-Aromatic Amides to O-Aromatic Esters

Glatzhofer, Daniel T.; et al, Organic Letters, 2002, 4(14), 2349-2352

合成路线：1 步

90-14-2

_91%

反应条件：

1.1 Reagents: Cesium carbonate Catalysts: Bis(dibenzylideneacetone)palladium , 9-[3,5-Bis(trifluoromethyl)phenyl]-4-(diphenylphosphino)acridine Solvents: Dimethylacetamide ; 24 h, 35 °C
1.2 Reagents: Sodium bicarbonate Solvents: Water

参考文献：

Shining Visible Light on Reductive Elimination: Acridine-Pd-Catalyzed Cross-Coupling of Aryl Halides with Carboxylic Acids

Toriumi, Naoyuki; et al, Journal of the American Chemical Society, 2022, 144(42), 19592-19602

合成路线：1 步

108-05-4

_90%

反应条件：

1.1 Catalysts: Dabco ; 10 min, 70 °C → 140 °C

参考文献：

The first vinyl acetate mediated organocatalytic transesterification of phenols: a step towards sustainability

Kumar, Manoj; et al, New Journal of Chemistry, 2015, 39(11), 8329-8336

合成路线：1 步

3396-11-0

90-11-9

_89%

反应条件：

1.1 Catalysts: Palladium trifluoroacetate , 4-[Bis(1,1-dimethylethyl)phosphino]-9-[3,5-bis(trifluoromethyl)phenyl]acridine Solvents: Dimethylacetamide ; 36 h, 35 °C
1.2 Reagents: Sodium bicarbonate Solvents: Water

参考文献：

Shining Visible Light on Reductive Elimination: Acridine-Pd-Catalyzed Cross-Coupling of Aryl Halides with Carboxylic Acids

Toriumi, Naoyuki; et al, Journal of the American Chemical Society, 2022, 144(42), 19592-19602

合成路线：1 步

62-23-7

_87%

反应条件：

1.1 Reagents: Trifluoroacetic anhydride , Phosphoric acid Solvents: Acetic acid , Water ; rt; rt; 5 min, rt

参考文献：

A TFAA-H3PO4-mediated direct, metal-free and high-speed synthesis of aryl carboxylate esters from phenols

Kankanala, Kavitha; et al, Journal of Fluorine Chemistry, 2009, 130(5), 505-508

合成路线：1 步

10387-40-3

_84%

反应条件：

1.1 Reagents: Oxygen Catalysts: Cupric acetate Solvents: Acetonitrile ; 8 h, 80 °C

参考文献：

Copper-Catalyzed Acetylation of Electron-Rich Phenols and Anilines

Zhang, Jieyu; et al, Synlett, 2019, 30(6), 726-730

合成路线：1 步

10387-40-3

_72%

反应条件：

1.1 Reagents: Carbon dioxide Solvents: Diglyme ; 8 h, 35 °C

参考文献：

CO2-Promoted Direct Acylation of Amines and Phenols by the Activation of Inert Thioacid Salts

Wang, Huan; et al, ChemSusChem, 2022, 15(10),

合成路线：1 步

91-20-3

_83%

反应条件：

1.1 Reagents: Acetic anhydride , Sodium nitrate Solvents: Trifluoroacetic acid ; 14 h, rt

参考文献：

Metal-free, Direct Acetoxylation of Arenes

Hong Nguyen, Thi Anh; et al, Organic Letters, 2021, 23(21), 8127-8131

合成路线：1 步

91-20-3

_72%

反应条件：

1.1 Reagents: Sodium acetate Solvents: Water

参考文献：

A one-pot electro oxidative nuclear and side chain acetoxylation of aromatic compounds at platinum electrode

Srivastav, Manish K.; et al, Oriental Journal of Chemistry, 2010, 26(1), 61-68

合成路线：1 步

630-08-0

103-54-8

_81%

反应条件：

1.1 Reagents: Acetic anhydride , Triethylamine Catalysts: Dichlorobis(triphenylphosphine)palladium Solvents: Benzene

参考文献：

Construction of polycyclic compounds by cyclocarbonylation. Part 5. Synthesis of benzofurans and benzothiophenes by palladium catalyzed cyclocarbonylation of 3-furylallyl and 3-thienylallyl acetates

Iwasaki, Masakazu; et al, Tetrahedron Letters, 1989, 30(1), 95-8

合成路线：1 步

80116-05-8

_78%

反应条件：

1.1 Catalysts: Ferric sulfate hydrate Solvents: 1,2-Dichloroethane ; rt; rt → reflux; 2 h, reflux

参考文献：

Convenient tetrahydropyranylation of alcohols and phenols by catalytic ferric sulfate hydrate (Fe2(SO4)3·xH2O)

Li, Lingjun; et al, Canadian Journal of Chemistry, 2005, 83(8), 1120-1123

合成路线：1 步

141-78-6

_78%

反应条件：

1.1 Catalysts: Poly(vinylpyrrolidone) , Zirconium chloride (ZrCl4) Solvents: Chloroform , Hexane ; 1.67 h, reflux

参考文献：

Polyvinylpyrrolidone-supported zirconium nanoparticles: synthesis, characterization, efficiency as a new polymer nanocomposite catalyst for one-step transesterification reaction

Azadi, Sedigheh; et al, Monatshefte fuer Chemie, 2023, 154(2), 239-248

合成路线：1 步

_76%

反应条件：

1.1 Reagents: Triethylamine Catalysts: Dichlorobis(triphenylphosphine)palladium

参考文献：

Palladium(II) chloride

Tsuji, Jiro; et al, e-EROS Encyclopedia of Reagents for Organic Synthesis, 2004, 1, 1-18

合成路线：1 步

反应条件：

1.1 Catalysts: Triethylamine , Dichlorobis(triphenylphosphine)palladium Solvents: Benzene ; 60 atm, 160 °C

参考文献：

Carbon Monoxide

Chatani, Naoto; et al, e-EROS Encyclopedia of Reagents for Organic Synthesis, 2001, ,

合成路线：1 步

反应条件：

1.1 Reagents: Triethylamine Catalysts: Dichlorobis(triphenylphosphine)palladium

参考文献：

Palladium(II) Chloride

Tsuji, Jiro; et al, e-EROS Encyclopedia of Reagents for Organic Synthesis, 2001, ,

合成路线：1 步

_75%

反应条件：

1.1 Reagents: Phosphorus pentoxide

参考文献：

P2O5/SiO2 as an efficient reagent for esterification of phenols in dry media

Eshghi, Hossien; et al, Synthetic Communications, 2001, 31(5), 771-774

合成路线：1 步