84-66-2 (邻苯二甲酸二乙酯,Diethyl phtalate)

_99%

反应条件：

1.1 Catalysts: Poly(oxy-1,2-ethanediyl), α-[2-[1-(3-sulfopropyl)-1H-imidazolium-3-yl]ethyl]-ω-[… Solvents: Toluene ; 1 h, 80 °C; 80 °C → rt

参考文献：

Synthesis of α,ω-bis[(3-sulfo propyl)-1H-imidazolium-1-yl]polyethylene glycol bis(hydrogen sulfate) and determination of its properties as thermomorphic ionic liquid and its activity as esterification catalyst

Zhi, Hui-Zhen; Luo, Jun; Ma, Wei; Lu, Chun-Xu, Gaodeng Xuexiao Huaxue Xuebao, 2008, 29(4), 772-774

合成路线：1 步

78-39-7

_99%

反应条件：

1.1 Solvents: 1-Butyl-3-methylimidazolium hexafluorophosphate ; 2 h, 80 °C

参考文献：

Efficient esterification of carboxylic acids and phosphonic acids with trialkyl orthoacetate in ionic liquid

Yoshino, Tomonori; Imori, Satomi; Togo, Hideo, Tetrahedron, 2006, 62(6), 1309-1317

合成路线：1 步

_97%

反应条件：

1.1 Catalysts: Chromate(2-), triaqua-μ3-oxotris[μ-[2-sulfo-1,4-benzenedicarboxylato(3-)-κO1:κO′… (reaction products with butanamine) ; 5 h, reflux

参考文献：

Synthesis and characterization of butylamine-functionalized Cr(III)-MOF-SO3H: Synergistic effect of the hydrophobic moiety on Cr(III)-MOF-SO3H in esterification reactions

Alavijeh, Masoumeh Karimi; Amini, Mostafa M., Polyhedron, 2019, 173,

合成路线：1 步

_96%

反应条件：

1.1 Catalysts: 2H-Imidazolium, 3-[2-[dimethyl(4-sulfobutyl)ammonio]ethyl]-1-methyl-, sulfate (1… Solvents: Toluene ; 3 h, 120 °C

参考文献：

Functionalized dicationic ionic liquids: Green and efficient alternatives for catalysts in phthalate plasticizers preparation

Zekri, Negar; Fareghi-Alamdari, Reza; Khodarahmi, Zahra, Journal of Chemical Sciences (Berlin, 2016, 128(8), 1277-1284

合成路线：1 步

_96%

反应条件：

1.1 Reagents: Desyl chloride Catalysts: [1,1′-Bis(diphenylphosphino)ferrocene]dichloropalladium Solvents: Ethanol ; 24 h, 60 °C

参考文献：

Palladium-Catalyzed Oxidative Carbonylation of Alkyl and Aryl Indium Reagents with CO under Mild Conditions

Zhao, Yingsheng; Jin, Liqun; Li, Peng; Lei, Aiwen, Journal of the American Chemical Society, 2008, 130(29), 9429-9433

合成路线：1 步

762-21-0

592-57-4

_96%

反应条件：

1.1 20 min

参考文献：

Synthesis of substituted furans and substituted benzenes via microwave enhanced Diels-Alder reactions

Hijji, Yousef M.; Wanene, Joseph; Obot, Emmanuel; Fuller, Jenora, International Electronic Conferences on Synthetic Organic Chemistry, 2004, 1977, 1977-1981

合成路线：1 步

_95%

反应条件：

1.1 Catalysts: Magnetite (Fe3O4) , Silica , 1H-Imidazolium, 3-[2,2-bis(hydroxymethyl)-3-(1-methyl-1H-imidazolium-3-yl)propyl… ; 8 h, 78 °C

参考文献：

Diacidic ionic liquid supported on magnetic-silica nanocomposite: a novel, stable, and reusable catalyst for selective diester production

Fareghi-Alamdari, Reza; Nadiri Niri, Mehri; Hazarkhani, Hassan; Zekri, Negar, Journal of the Iranian Chemical Society, 2018, 15(11), 2615-2629

合成路线：1 步

_94%

反应条件：

1.1 Catalysts: 1H-Benzimidazole, 1-ethyl-, tetrafluoroborate(1-) (1:1) Solvents: 1H-Benzimidazole, 1-ethyl-, tetrafluoroborate(1-) (1:1) ; 4 h, 130 °C

参考文献：

Preparation and characterization of a novel benzimidazolium Bronsted acid ionic liquid and its application in the synthesis of acrylic esters

Wang, Yuan-Yuan; Li, Wei; Xu, Cheng-Di; Dai, Li-Yi, Chinese Journal of Chemistry, 2007, 25(1), 68-71

合成路线：1 步

_93%

反应条件：

1.1 Catalysts: Graphene (oxide, sulfonated) Solvents: Ethanol ; 3 h, reflux

参考文献：

Sulfonated graphene as highly efficient and reusable acid carbocatalyst for the synthesis of ester plasticizers

Garg, Bhaskar; Bisht, Tanuja; Ling, Yong-Chien, RSC Advances, 2014, 4(100), 57297-57307

合成路线：1 步

_92%

反应条件：

1.1 Catalysts: Sulfuric acid Solvents: Ethanol ; 12 h, 100 °C; 100 °C → rt
1.2 Reagents: Sodium carbonate Solvents: Water ; neutralized, rt

参考文献：

Noncovalent interactions in Ir-catalyzed C-H activation: L-shaped ligand for para-selective borylation of aromatic esters

Hoque, Emdadul Md; Bisht, Ranjana; Haldar, Chabush; Chattopadhyay, Buddhadeb, Journal of the American Chemical Society, 2017, 139(23), 7745-7748

合成路线：1 步

_90%

反应条件：

1.1 Catalysts: Dichlorobis(triphenylphosphine)palladium Solvents: Ethanol ; 24 h, rt
1.2 Reagents: Ammonium chloride Solvents: Water

参考文献：

Base-Induced Mechanistic Variation in Palladium-Catalyzed Carbonylation of Aryl Iodides

Hu, Yanhe; Liu, Jing; Lu, Zhixin; Luo, Xiancai; Zhang, Heng; et al, Journal of the American Chemical Society, 2010, 132(9), 3153-3158

合成路线：1 步

4170-30-3

762-21-0

_90%

反应条件：

1.1 Reagents: Acetamide Catalysts: p-Toluenesulfonic acid Solvents: N-Methyl-2-pyrrolidone ; 24 h, 120 °C

参考文献：

Unusual coupling reactions of aldehydes and alkynes: A novel preparation of substituted phthalic acid derivatives by automated synthesis

von Wangelin, Axel Jacobi; Neumann, Helfried; Gordes, Dirk; Klaus, Stefan; Jiao, Haijun; et al, Chemistry - A European Journal, 2003, 9(10), 2273-2281

合成路线：1 步

5048-50-0

_89%

反应条件：

1.1 Reagents: Sulfuric acid magnesium salt (1:1) , Oxygen Catalysts: Sodium 9,10-anthraquinone-2-sulfonate , Palladium trifluoroacetate Solvents: Chlorobenzene ; 24 h, 1 atm, 110 °C

参考文献：

Palladium-Catalyzed Aerobic Oxidative Dehydrogenation of Cyclohexenes to Substituted Arene Derivatives

Iosub, Andrei V.; Stahl, Shannon S., Journal of the American Chemical Society, 2015, 137(10), 3454-3457

合成路线：1 步

109-63-7

_87%

反应条件：

1.1 4 h, rt → 120 °C

参考文献：

Unprecedented alkylation of carboxylic acids by boron trifluoride etherate

Jumbam, Ndze D.; Maganga, Yamkela; Masamba, Wayiza; Mbunye, Nomthandazo I.; Mgoqi, Esethu; et al, Bulletin of the Chemical Society of Ethiopia, 2018, 32(2), 387-392

合成路线：1 步

_87%

反应条件：

1.1 Catalysts: Chromate(5-), triaquatris[μ-[4,8-disulfo-2,6-naphthalenedicarboxylato(4-)-κO2:κO… Solvents: Cyclohexane ; 8 h, 170 °C

参考文献：

Highly Efficient Catalytic Esterification in an -SO3H-Functionalized Cr(III)-MOF

Dou, Yibo; Zhang, Heng; Zhou, Awu; Yang, Fan; Shu, Lun; et al, Industrial & Engineering Chemistry Research, 2018, 57(25), 8388-8395

合成路线：1 步

22919-28-4

762-21-0

_87%