86365-83-5 (1,3-dibromobut-2-ene,2-Butene, 1,3-dibromo-, (2E)- (9CI, ACI))

快速询单

结构式：

1,3-dibromobut-2-eneMOL文件

CAS号：

86365-83-5

中文名称：

1,3-dibromobut-2-ene

英文名称：

2-Butene, 1,3-dibromo-, (2E)- (9CI, ACI)

分子式：

C₄H₆Br₂

分子量：

213.898439884186

1,3-dibromobut-2-ene(86365-83-5)名称与标识符

名称

中文别名：

1,3-dibromobut-2-ene;

英文别名：

(2E)-1,3-Dibromo-2-butene (ACI);2-Butene, 1,3-dibromo-, (E)- (ZCI);

标识符

InChIKey：

CXCKBPHWDONPBF-DUXPYHPUSA-N

Inchi：

1S/C4H6Br2/c1-4(6)2-3-5/h2H,3H2,1H3/b4-2+

SMILES：

C(/CBr)=C(/C)\Br

1,3-dibromobut-2-ene(86365-83-5)推荐厂家更多厂家(1)

公司名称	手机号/电话	联系人	QQ	微信	询单
上海楷森生物科技有限公司	17558870519 175-58870519	赵经理			询单

1,3-dibromobut-2-ene(86365-83-5)合成路线

合成路线：1 步

37428-56-1

_92%

86365-83-5

反应条件：

1.1 Reagents: Phosphorus tribromide Solvents: Diethyl ether ; rt → 0 °C; 5 min, 0 °C; 15 min, 0 °C

参考文献：

Constructing the architecturally distinctive ABD-tricycle of phomactin A through an intramolecular oxa-[3+3] annulation strategy

Buchanan, Grant S.; et al, Tetrahedron, 2011, 67(52), 10105-10118

合成路线：1 步

37428-56-1

_92%

86365-83-5

反应条件：

1.1 Reagents: Phosphorus tribromide Solvents: Diethyl ether ; rt → 0 °C; 5 min, 0 °C; 15 min, 0 °C

参考文献：

An enantioselective synthesis of the ABD tricycle for (-)-phomactin A featuring Rawal's asymmetric Diels-Alder cycloaddition

You, Ling-Feng; et al, Advanced Synthesis & Catalysis, 2008, 350(18), 2885-2891

合成路线：1 步

37428-56-1

86365-83-5

参考文献：

Studies toward brevisulcenal F via convergent strategies for marine ladder polyether synthesis

Katcher, Matthew H.; et al, Tetrahedron, 2018, 74(11), 1111-1122

合成路线：1 步

105479-82-1

86365-83-5

反应条件：

1.1 Reagents: Lithium bromide Solvents: Tetrahydrofuran

参考文献：

Vinyl radical cyclization in the synthesis of natural products: seychellene

Stork, Gilbert; et al, Tetrahedron Letters, 1985, 26(48), 5927-30

合成路线：2 步

37428-56-1

124-63-0

86365-83-5

反应条件：

1.1 Reagents: Triethylamine Solvents: Dichloromethane
2.1 Reagents: Lithium bromide Solvents: Tetrahydrofuran

参考文献：

Vinyl radical cyclization in the synthesis of natural products: seychellene

Stork, Gilbert; et al, Tetrahedron Letters, 1985, 26(48), 5927-30

合成路线：2 步

22122-36-7

86365-83-5

参考文献：

Studies toward brevisulcenal F via convergent strategies for marine ladder polyether synthesis

Katcher, Matthew H.; et al, Tetrahedron, 2018, 74(11), 1111-1122

合成路线：2 步

4021-75-4

86365-83-5

反应条件：

1.1 Reagents: Lithium diisopropylamide
1.2 Solvents: Tetrahydrofuran ; < -70 °C; 90 min, < -70 °C; 2 h, < -70 °C
1.3 Reagents: Methanol ; < -70 °C; < -70 °C → rt
1.4 Reagents: Hydrochloric acid Solvents: Water ; acidified, rt
2.1 Reagents: Phosphorus tribromide Solvents: Diethyl ether ; rt → 0 °C; 5 min, 0 °C; 15 min, 0 °C

参考文献：

Constructing the architecturally distinctive ABD-tricycle of phomactin A through an intramolecular oxa-[3+3] annulation strategy

Buchanan, Grant S.; et al, Tetrahedron, 2011, 67(52), 10105-10118

合成路线：2 步

54899-03-5

86365-83-5

反应条件：

1.1 Reagents: Hexamethylphosphoramide , Lithium diisopropylamide Solvents: Tetrahydrofuran ; 0 °C; 90 min, < -70 °C; 2 h
2.1 Reagents: Phosphorus tribromide Solvents: Diethyl ether ; rt → 0 °C; 5 min, 0 °C; 15 min, 0 °C

参考文献：

An enantioselective synthesis of the ABD tricycle for (-)-phomactin A featuring Rawal's asymmetric Diels-Alder cycloaddition

You, Ling-Feng; et al, Advanced Synthesis & Catalysis, 2008, 350(18), 2885-2891

合成路线：3 步

504-61-0

86365-83-5

反应条件：

1.1 Reagents: Bromine Solvents: Dichloromethane ; rt → -40 °C; -40 - -30 °C; -30 °C → rt
2.1 Reagents: Lithium diisopropylamide
2.2 Solvents: Tetrahydrofuran ; < -70 °C; 90 min, < -70 °C; 2 h, < -70 °C
2.3 Reagents: Methanol ; < -70 °C; < -70 °C → rt
2.4 Reagents: Hydrochloric acid Solvents: Water ; acidified, rt
3.1 Reagents: Phosphorus tribromide Solvents: Diethyl ether ; rt → 0 °C; 5 min, 0 °C; 15 min, 0 °C

参考文献：

Constructing the architecturally distinctive ABD-tricycle of phomactin A through an intramolecular oxa-[3+3] annulation strategy

Buchanan, Grant S.; et al, Tetrahedron, 2011, 67(52), 10105-10118

合成路线：3 步

6117-91-5

86365-83-5

反应条件：

1.1 Reagents: Bromine Solvents: Dichloromethane ; rt → -40 °C; -40 - -30 °C; -40 °C → rt
2.1 Reagents: Hexamethylphosphoramide , Lithium diisopropylamide Solvents: Tetrahydrofuran ; 0 °C; 90 min, < -70 °C; 2 h
3.1 Reagents: Phosphorus tribromide Solvents: Diethyl ether ; rt → 0 °C; 5 min, 0 °C; 15 min, 0 °C

参考文献：

An enantioselective synthesis of the ABD tricycle for (-)-phomactin A featuring Rawal's asymmetric Diels-Alder cycloaddition

You, Ling-Feng; et al, Advanced Synthesis & Catalysis, 2008, 350(18), 2885-2891

合成路线：3 步

69169-56-8

86365-83-5

反应条件：

1.1 Reagents: Lithium aluminum hydride Solvents: Tetrahydrofuran
2.1 Reagents: Triethylamine Solvents: Dichloromethane
3.1 Reagents: Lithium bromide Solvents: Tetrahydrofuran

参考文献：

Vinyl radical cyclization in the synthesis of natural products: seychellene

Stork, Gilbert; et al, Tetrahedron Letters, 1985, 26(48), 5927-30

合成路线：1 步