876-27-7 (乙酸-4-氯苯酯,4-Chlorophenyl acetate)

_100%

反应条件：

1.1 Catalysts: 1-Butanaminium, N,N,N-tributyl-, (dichlorostannate)octatetraconta-μ-oxotetra-μ6-… Solvents: Acetonitrile ; 6 min, rt

参考文献：

New porphyrin-polyoxometalate hybrid materials: synthesis, characterization and investigation of catalytic activity in acetylation reactions

Araghi, Mehdi; et al, Dalton Transactions, 2012, 41(38), 11745-11752

合成路线：1 步

_100%

反应条件：

1.1 Catalysts: (OC-6-13)-[[2,2′-[1,2-Phenylenebis[(nitrilo-κN)methylidyne]]bis[phenolato-κO]](2… Solvents: Dichloromethane ; 1 min, rt

参考文献：

Electron-deficient [TiIV(salophen)(OTf)2]: A new and highly efficient catalyst for the acetylation of alcohols and phenols with acetic anhydride

Yadegari, Maryam; et al, Polyhedron, 2011, 30(13), 2237-2243

合成路线：1 步

_100%

反应条件：

1.1 Catalysts: (OC-6-12)-[[4,4′,4′′,4′′′-(21H,23H-Porphine-5,10,15,20-tetrayl-κN21,κN22,κN23,κN… (supported on chloromethylated polystyrene) Solvents: Acetonitrile ; 8 min, rt

参考文献：

Polystyrene-bound electron-deficient tin(IV) porphyrin: A new, highly efficient, robust and reusable catalyst for acetylation of alcohols and phenols with acetic anhydride

Moghadam, Majid; et al, Comptes Rendus Chimie, 2011, 14(12), 1080-1087

合成路线：1 步

75-36-5

_100%

反应条件：

1.1 Catalysts: Titania ; 5 min, 25 °C

参考文献：

TiO2, a simple and an efficient catalyst for esterification of phenols under solvent-free condition

Pasha, Mohamed Afzal; et al, Indian Journal of Chemistry, 2008, (4), 597-600

合成路线：1 步

75-36-5

_99%

反应条件：

1.1 Reagents: Pyridine Solvents: Dichloromethane ; 0 °C → rt; 3 h, rt

参考文献：

NIS/TBHP Induced Regioselective Selenation of (Hetero)Arenes via Direct C-H Functionalization

Ding, Chaochao; et al, ChemCatChem, 2018, 10(23), 5397-5401

合成路线：1 步

75-36-5

_98%

反应条件：

1.1 Reagents: Pyridine Solvents: Dichloromethane ; 0 °C → rt; 5 h, rt

参考文献：

Synthesis and anti-inflammatory activity of 2-oxo-2H-chromenyl and 2H-chromenyl-5-oxo-2,5-dihydrofuran-3-carboxylates

Kurma, Siva Hariprasad; et al, Bioorganic & Medicinal Chemistry Letters, 2020, 30(16),

合成路线：1 步

10557-71-8

64-19-7

_97%

反应条件：

1.1 Reagents: Bis(trifluoroacetoxy)iodobenzene Catalysts: Palladium diacetate Solvents: Acetic acid ; 17 h, 80 °C
1.2 Reagents: Sodium bicarbonate Solvents: Water

参考文献：

Palladium-Catalyzed Desilylative Acyloxylation of Silicon-Carbon Bonds on (Trimethylsilyl)arenes: Synthesis of Phenol Derivatives from Trimethylsilylarenes

Gondo, Keisuke; et al, Organic Letters, 2015, 17(19), 4778-4781

合成路线：1 步

64-19-7

_97%

反应条件：

1.1 Catalysts: Cesium hydrogen tetracosa-μ-oxododecaoxo[μ12-[phosphato(3-)-κO:κO:κO:κO′:κO′:κO′… Solvents: Acetonitrile ; 30 min, 50 °C

参考文献：

Characterization of novel Cs and K substituted phosphotungstic acid modified MCM-41 catalyst and its catalytic activity towards acetylation of aromatic alcohols

Rana, Surjyakanta; et al, Journal of Chemical Sciences (Bangalore, 2012, 124(5), 1117-1125

合成路线：1 步

108-05-4

_96%

反应条件：

1.1 Catalysts: Dabco ; 10 min, 70 °C → 140 °C

参考文献：

The first vinyl acetate mediated organocatalytic transesterification of phenols: a step towards sustainability

Kumar, Manoj; et al, New Journal of Chemistry, 2015, 39(11), 8329-8336

合成路线：1 步

99-91-2

_96%

反应条件：

1.1 Reagents: 4-Aminobenzenecarboperoxoic acid (silica supported) Catalysts: Hydrochloric acid , Water Solvents: Chloroform ; 12 h, rt

参考文献：

Efficient method for oxidation of ketones to esters with 4-aminoperoxybenzoic acid supported on silica gel

Ghazanfari, Dadkhoda; et al, Synthetic Communications, 2008, 38(12), 2037-2042

合成路线：1 步

99-91-2

_95%

反应条件：

1.1 Reagents: Phosphoroperoxoic acid Solvents: Acetonitrile ; 30 °C

参考文献：

Monoperoxyphosphoric acid

Rao, A. Somasekar; et al, e-EROS Encyclopedia of Reagents for Organic Synthesis, 2001, 1,

合成路线：1 步

99-91-2

_95%

反应条件：

1.1 Reagents: Phosphorus pentoxide , Hydrogen peroxide ; 30 °C

参考文献：

The Baeyer-Villiger oxidation of ketones and aldehydes

Krow, Grant R., Organic Reactions (Hoboken, 1993, 43,

合成路线：1 步

13871-68-6

_93%

反应条件：

1.1 Reagents: Tetraethylammonium chloride , Boron trifluoride etherate Catalysts: Cuprous chloride , 1-Propanaminium, N,N,N-triethyl-, chloride (1:1) (silica supported) Solvents: Acetonitrile ; 10 min, 0 °C
1.2 Reagents: tert-Butyl nitrite Solvents: Acetonitrile ; 1 h, 20 °C

参考文献：

Highly efficient Sandmeyer reaction on immobilized CuI/CuII-based catalysts

Tarkhanova, Irina G.; et al, Mendeleev Communications, 2018, 28(3), 261-263

合成路线：1 步

177490-82-3

_93%

反应条件：

1.1 Reagents: Chlorosuccinimide Catalysts: 1-(1,1-Dimethylethyl) (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate (MCM-41 supported copper chloride complex) Solvents: Acetonitrile ; 12 h, 80 °C

参考文献：

A highly efficient heterogeneous copper-catalyzed chlorodeboronation of arylboronic acids leading to chlorinated arenes

He, Wen; et al, RSC Advances, 2017, 7(2), 764-770

合成路线：1 步

177490-82-3

_93%

反应条件：

1.1 Reagents: Chlorosuccinimide Catalysts: Cuprous chloride Solvents: Acetonitrile ; 3 h, 80 °C

参考文献：

Copper-Catalyzed Chlorination of Functionalized Arylboronic Acids

Wu, Hong; et al, Organic Letters, 2010, 12(6), 1192-1195

合成路线：1 步

60179-40-0

_93%

反应条件：

1.1 Catalysts: Triethylamine Solvents: Toluene ; 12 h, reflux

参考文献：

Environmentally benign decarboxylative N-, O-, and S-acetylations and acylations

Ghosh, Santanu; et al, Green Chemistry, 2020, 22(24), 8721-8727

合成路线：1 步

2033-24-1

_91%

反应条件：

1.1 Catalysts: Triethylamine Solvents: Anisole ; 12 h, 110 °C

参考文献：

Environmentally benign decarboxylative N-, O-, and S-acetylations and acylations

Ghosh, Santanu; et al, Green Chemistry, 2020, 22(24), 8721-8727

合成路线：1 步

506-96-7

_91%

反应条件：

1.1 Reagents: Potassium carbonate Solvents: N-Methyl-2-pyrrolidone ; 4 h, rt; 24 h, rt
1.2 Reagents: Lithium bromide Solvents: Dichloromethane ; 24 h, rt

参考文献：

Counterattack Mode Differential Acetylative Deprotection of Phenylmethyl Ethers: Applications to Solid Phase Organic Reactions

Chakraborti, Asit K.; et al, Journal of Organic Chemistry, 2009, 74(3), 1367-1370

合成路线：1 步

17005-59-3

_90%

反应条件：

1.1 Catalysts: Bismuth triflate Solvents: Acetonitrile

参考文献：

Efficient and selective conversion of trimethylsilyl and tetrahydropyranyl ethers to their corresponding acetates and benzoates catalyzed by bismuth(III) salts

Mohammadpoor-Baltork, Iraj; et al, Monatshefte fuer Chemie, 2002, 133(2), 189-193

合成路线：1 步

17005-59-3

_84%

反应条件：

1.1 Catalysts: Boron trifluoride etherate (reaction product with poly(vinylpyrrolidone)) Solvents: Acetonitrile ; 1 h, rt

参考文献：

Polyvinylpolypyrrolidone-bound boron trifluoride: A highly efficient catalyst for acylation of alcohols, phenols and trimethylsilyl ethers by acetic anhydride

Mokhtary, Masoud; et al, Comptes Rendus Chimie, 2012, 15(5), 389-393

合成路线：1 步

17005-59-3

_82%

反应条件：

1.1 Catalysts: Sulfuric acid (silica-bound) Solvents: Dichloromethane ; 35 min, rt

参考文献：

An efficient and convenient method for desilylation-acetylation of trimethylsilyl ethers catalyzed by silica sulfuric acid

Jin, Tong-Shou; et al, Asian Journal of Chemistry, 2008, 20(7), 5005-5010

合成路线：1 步

126644-72-2

_87%

反应条件：

1.1 Catalysts: Perchloric acid , Silica Solvents: Dichloromethane ; 10 h, rt

参考文献：

An atom-efficient and powerful method for direct esterification of silyl ethers catalyzed by HClO4-SiO2

Du, Ti-Jian; et al, Tetrahedron, 2011, 67(6), 1096-1101

合成路线：1 步

2052928-07-9

110-82-7

_87%

反应条件：

1.1 Reagents: tert-Butyl peroxide ; 24 h, rt → 90 °C

参考文献：

Copper Catalyzed sp3 C-H Etherification with Acyl Protected Phenols

Salvador, Tolani K.; et al, Journal of the American Chemical Society, 2016, 138(51), 16580-16583

合成路线：1 步

141-78-6

_85%