921-01-7 (D-半胱氨酸,D-Cysteine)

参考文献：

Enzymatic synthesis of D-cysteine by 3-chloro-D-alanine resistant Pseudomonas putida CR 1-1

Nagasawa, Toru; Yamano, Hironori; Ohkishi, Haruyuki; Hosono, Hidekazu; Tani, Yoshiki; et al, Agricultural and Biological Chemistry, 1982, 46(12), 3003-10

合成路线：1 步

39217-38-4

_94%

参考文献：

Synthesis of D-cysteine from a racemate of 3-chloroalanine by phenylhydrazine-treated cells of Pseudomonas putida CR 1-1

Nagasawa, Toru; Hosono, Hidekazu; Yamano, Hironori; Ohkishi, Haruyuki; Tani, Yoshiki; et al, Agricultural and Biological Chemistry, 1983, 47(4), 861-8

合成路线：1 步

58166-38-4

_86%

反应条件：

1.1 Solvents: Water ; 1.5 h, 80 °C
1.2 Reagents: Triethylamine ; pH 5

参考文献：

Study of the process for preparation of D-homocysteine from L-homocysteine hydrochloride

Zhao, Min-juan; Li, Ning-ning; Lu, Jiu-fu, Zhejiang Huagong, 2012, 43(11), 18-21

合成路线：1 步

_83%

反应条件：

1.1 Reagents: Water ; 1.5 h, rt → reflux
1.2 Reagents: Triethylamine ; pH 5
1.3 Reagents: Ethanol ; 10 min

参考文献：

New process for preparation of D-cysteine from L-cysteine by asymmetric

Yu, Mingjun; Jiang, Lijian; Wu, Liuyang; Li, Jianjun, Yingyong Huagong, 2007, 36(5), 488-490

合成路线：1 步

45521-09-3

_82%

反应条件：

1.1 Reagents: Hydroxyamine hydrochloride

参考文献：

Optical resolution by preferential crystallization of DL-thiazolidine-4-carboxylic acid

Shiraiwa, Tadashi; Sado, Yujin; Komure, Masamitsu; Kurokawa, Hidemoto, Chemistry Letters, 1987, (4), 621-2

合成路线：1 步

3374-22-9

_79%

反应条件：

1.1 Reagents: Hydrochloric acid Solvents: Water ; rt → 100 °C
1.2 Reagents: L-Dibenzoyltartaric acid ; 30 min, 80 - 100 °C; 1 h, 60 °C; 60 °C → 15 °C
1.3 Reagents: Triethylamine Solvents: Ethanol ; 1 h, 15 °C

参考文献：

Chemical resolution of L-cysteine and D-cysteine

, China, , ,

合成路线：1 步

反应条件：

1.1 Reagents: Hexadecyltrimethylammonium bromide , Ammonia , Chloroauric acid Catalysts: Cobalt chloride (CoCl2) Solvents: Water ; 25 °C; 7 h, pH 7, 70 °C

参考文献：

Preparation method of chiral cobalt oxide-gold hollow nanomaterial

, China, , ,

合成路线：1 步

3374-22-9

参考文献：

Sonochemically modified ovalbumin enhances enantioenrichment of some amino acids

Mutalikdesai, Amruta; Nassir, Molhm; Saady, Abed; Hassner, Alfred; Gedanken, Aharon, Ultrasonics Sonochemistry, 2019, 58,

合成路线：1 步

58166-38-4

反应条件：

1.1 Reagents: Water ; 1.5 h, reflux
1.2 Reagents: Ammonia Solvents: Water ; pH 3

参考文献：

Method for preparing D-cysteine hydrochloride monohydrate having high optical purity

, China, , ,

合成路线：1 步

52-90-4

反应条件：

1.1 Reagents: Acetic acid , Propionic acid Solvents: Acetone ; 0.5 h, 80 °C
1.2 10 h, 80 °C
1.3 Reagents: L-Phenylalanine ; 0.2 h, 80 °C
1.4 Reagents: Water ; 2 h, heated
1.5 Reagents: Sodium hydroxide Solvents: Water ; pH 4.9

参考文献：

A simple method for producing D-cysteine with L-cysteine as raw material

, China, , ,

合成路线：1 步

3374-22-9

反应条件：

1.1 Reagents: Hydrochloric acid Catalysts: Tryptophanase Solvents: Water ; 13 h, 35 °C

参考文献：

Manufacture of D-cysteine from cysteine by enzymic resolution

, China, , ,

合成路线：1 步

147-71-7

反应条件：

1.1 Reagents: Water ; 3 h, 1 atm, 60 °C
1.2 Reagents: Ammonia Solvents: Water ; pH 3.5

参考文献：

Process for preparation of D-cystine

, China, , ,

合成路线：1 步

反应条件：

1.1 Solvents: Water ; 1.5 h, reflux
1.2 Reagents: Triethylamine ; pH 3.6

参考文献：

Process for preparation of D-cysteine hydrochloride monohydrate

, China, , ,

合成路线：1 步

24583-23-1

反应条件：

1.1 Reagents: Sodium hydroxide , Phosphoric acid Solvents: Water ; rt; pH 7.2, rt → 40 °C; 44 h, pH 7.2

参考文献：

Process for the enzymic preparation of enantiomerically enriched D-amino acids

, World Intellectual Property Organization, , ,

合成路线：1 步

参考文献：

Asymmetric transformation of (RS)-cysteine via formation of (RS)-4-thiazolidinecarboxylic acids

Shiraiwa, Tadashi; Kataoka, Kazuo; Sakata, Shinji; Kurokawa, Hidemoto, Bulletin of the Chemical Society of Japan, 1989, 62(1), 109-13

合成路线：1 步

349-46-2

参考文献：

Optical resolution of (R, S)-cysteine

, Japan, , ,

合成路线：1 步

34592-47-7

参考文献：

Optically active cysteins

, Japan, , ,

合成路线：1 步

3981-36-0

参考文献：

Production of D-cysteine derivatives

, Japan, , ,

合成路线：1 步

2731-73-9