93-16-3 (异丁香酚甲醚,Methyl isoeugenol)

_100%

反应条件：

1.1 Catalysts: (SP-5-41)-[1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro[[2-(1-m… Solvents: Toluene ; 18 h, reflux

参考文献：

Synthesis of Alkenyl Boronates from Allyl-Substituted Aromatics Using an Olefin Cross-Metathesis Protocol

Hemelaere, Remy; Carreaux, Francois; Carboni, Bertrand, Journal of Organic Chemistry, 2013, 78(13), 6786-6792

合成路线：1 步

_100%

反应条件：

1.1 Catalysts: Ruthenium, [(1,2,5,6-η)-1,5-cyclooctadiene]bis[(1,2,3-η)-2-methyl-2-propenyl]- ; 1 min, 150 °C

参考文献：

Selective catalytic alkene isomerization for making fragrance ingredients or intermediates

, World Intellectual Property Organization, , ,

合成路线：1 步

74-88-4

_99%

反应条件：

1.1 Reagents: Potassium carbonate Solvents: Dimethylformamide ; 6 h, rt

参考文献：

Epoxy resin composition with excellent thermal properties

, Korea, , ,

合成路线：1 步

74-88-4

_99%

反应条件：

1.1 Reagents: Potassium carbonate Solvents: Dimethylformamide ; 6 h, rt

参考文献：

Synthesis of isoeugenol biobased epoxy polymer by forming α-hydroxyl ester and degradation studies

Sivanesan, Dharmalingam; Seo, Bongkuk; Lim, Choong-Sun; Song, Jinyoung; Kim, Hyeon-Gook, Journal of Applied Polymer Science, 2022, 139(12),

合成路线：1 步

_99%

反应条件：

1.1 Catalysts: Benzenesulfonic acid, 4-methyl-, ruthenium(2+) salt, hydrate (2:1:6) Solvents: Water

参考文献：

Isomerization of olefins catalyzed by the hexaaquaruthenium(2+) ion

Karlen, Thomas; Ludi, Andreas, Helvetica Chimica Acta, 1992, 75(5), 1604-6

合成路线：1 步

72898-29-4

74-88-4

_98%

反应条件：

1.1 Reagents: Potassium hydroxide Solvents: Dimethyl sulfoxide ; 1 h, 25 °C
1.2 10 h, 25 °C
1.3 Reagents: Water ; 25 °C

参考文献：

Sustainable Production of Bioactive Molecules from C-Lignin-Derived Propenylcatechol

Song, Weihong; Du, Qinglian; Li, Xiancheng; Wang, Shuizhong; Song, Guoyong, ChemSusChem, 2022, 15(14),

合成路线：1 步

616-38-6

97-53-0

_98%

反应条件：

1.1 Reagents: Potassium carbonate Catalysts: Polyethylene glycol ; rt → 170 °C; 3 h, 170 °C; 1 h, 170 °C; cooled
1.2 Reagents: Hydrochloric acid Solvents: Water ; neutralized, cooled

参考文献：

Method for synthesizing methylisoeugenol

, China, , ,

合成路线：1 步

_98%

反应条件：

1.1 Reagents: 2,8-Bis(1-methylethyl)-2,5,8,9-tetraaza-1-phosphabicyclo[3.3.3]undecane Solvents: Acetonitrile ; 24 h, 40 °C

参考文献：

Synthesis of Di-substituted proazaphosphatrane and its application in carbon-carbon double-bond isomerization

Wu, Wei; Zhang, Xiao-yun; Kang, Shou-xing, Chemical Research in Chinese Universities, 2010, 26(5), 768-772

合成路线：1 步

616-38-6

_97%

反应条件：

1.1 Catalysts: Dimethyl sulfide Solvents: Dimethyl carbonate ; 4 h, rt → 220 °C

参考文献：

Methylation with Dimethyl Carbonate/Dimethyl Sulfide Mixtures: An Integrated Process without Addition of Acid/Base and Formation of Residual Salts

Lui, Yuen Wai; Chan, Bun ; Lui, Matthew Y., ChemSusChem, 2022, 15(3),

合成路线：1 步

_97%

反应条件：

1.1 Catalysts: 2,8,9-Trimethyl-2,5,8,9-tetraaza-1-phosphabicyclo[3.3.3]undecane Solvents: Acetonitrile ; 96 h, 40 °C

参考文献：

Synthesis of bis(isobutyl)azaphosphatrane and its use in double-bond isomerization

Wu, Wei; Zhang, Xiaoyun; Peng, Wei, Huaxue Tongbao, 2010, 73(5), 461-464

合成路线：1 步

_95%

反应条件：

1.1 Catalysts: Sodium hydroxide , Sodium ; 2 h, rt

参考文献：

Catalytic modification of eugenol over superbase catalyst Na/NaOH/γ-Al2O3

Sutanto, Hery; Si, M.; Wibowo, Widajanti; Cahyana, A. Herry, Proceedings of the Annual International Conference on Chemistry, 2013, 1, 20-23

合成路线：1 步

_90%

反应条件：

1.1 Reagents: Formaldehyde Catalysts: Triphenylphosphine , Rhodium, tetrakis[μ-(hexahydro-2H-azepin-2-onato-κN1:κO2)]di-, (Rh-Rh) Solvents: Toluene ; 20 h, 90 °C

参考文献：

Valorisation of biobased olefins via Rh-catalyzed transfer hydroformylation and isomerization using formaldehyde as a CO/H2 surrogate

Concha-Puelles, Matias; Cortinez, Antonio; Lezana, Nicolas; Vilches-Herrera, Marcelo; Luhr, Susan, Catalysis Science & Technology, 2022, 12(22), 6883-6890

合成路线：1 步

_87%

反应条件：

1.1 Reagents: Potassium tert-butoxide Solvents: Dimethyl sulfoxide ; 4 h, reflux

参考文献：

Synthesis 3,4-dimethoxybenzyl-2,4-dihydroxyphenyl ketone from eugenol

Matsjeh, S.; Anwar, C.; Sholikhah, E. N.; Alimuddin, A. A., International Journal of Chemical Engineering and Applications, 2015, 6(1), 61-65

合成路线：1 步

616-38-6

97-53-0

_84%

反应条件：

1.1 Reagents: Potassium hydroxide Catalysts: Polyethylene glycol ; 2 h, 2 - 3 MPa, rt → 200 °C; 3 h, 200 °C

参考文献：

Simple and environmentally-friendly method for synthesizing isoeugenol methyl ether

, China, , ,

合成路线：1 步

74-96-4

120-14-9

_75%

反应条件：

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran ; rt
1.2 Solvents: Tetrahydrofuran ; rt; 2 h, rt

参考文献：

Synthesis, antifeedant activity against Coleoptera and 3D QSAR study of alpha-asarone derivatives

Lozowicka, B.; Kaczynski, P.; Magdziarz, T.; Dubis, A. T., SAR and QSAR in Environmental Research, 2014, 25(3), 173-188

合成路线：1 步

111222-50-5

_56%

反应条件：

1.1 Solvents: Diethyl ether , Chloroform

参考文献：

Reactions of some N-acyl-1-alkylamines with polyphosphoric ester PPE: nuclear magnetic resonance and stereochemistry of reaction products

Alesso, Elba N.; Tombari, Dora G.; Moltrasio Iglesias, Graciela Y.; Aguirre, Jose M., Canadian Journal of Chemistry, 1987, 65(11), 2568-74

合成路线：1 步

_36%

反应条件：

1.1 Reagents: Sodium dodecyl sulfate Catalysts: 1947407-22-8 Solvents: Water ; 10 min, rt
1.2 18 h, 95 °C

参考文献：

Micellar promoted alkenes isomerization in water mediated by a cationic half-sandwich Ru(II) complex

Sperni, Laura; Scarso, Alessandro; Strukul, Giorgio, Inorganica Chimica Acta, 2017, 455, 535-539

合成路线：1 步

反应条件：

1.1 Catalysts: (SP-5-41)-[1,3-Bis[2,6-bis(1-methylethyl)phenyl]-2-imidazolidinylidene]dichloro[… Solvents: Toluene ; 1 h, reflux

参考文献：

Ruthenium-Catalyzed One-Pot Synthesis of (E)-(2-Arylvinyl)boronates through an Isomerization/Cross-Metathesis Sequence from Allyl-Substituted Aromatics

Hemelaere, Remy; Caijo, Frederic; Mauduit, Marc; Carreaux, Francois; Carboni, Bertrand, European Journal of Organic Chemistry, 2014, 2014(16), 3328-3333

合成路线：1 步

29908-03-0

反应条件：

1.1 Catalysts: Methyltransferase Solvents: Water ; 18 h, pH 7.4, 30 °C

参考文献：

One-Pot Biocatalytic In Vivo Methylation-Hydroamination of Bioderived Lignin Monomers to Generate a Key Precursor to L-DOPA

Galman, James L. ; Parmeggiani, Fabio ; Seibt, Lisa ; Birmingham, William R. ; Turner, Nicholas J., Angewandte Chemie, 2022, 61(8),

合成路线：1 步

1530-32-1

120-14-9