93319-65-4 (3-哒嗪甲胺,Pyridazin-3-ylmethanamine)

快速询单

结构式：

3-哒嗪甲胺MOL文件

CAS号：

93319-65-4

中文名称：

3-哒嗪甲胺

英文名称：

Pyridazin-3-ylmethanamine

分子式：

C₅H₇N₃

分子量：

109.129180192947

3-哒嗪甲胺(93319-65-4)名称与标识符

名称

中文别名：

3-哒嗪甲胺;3-吡嗪甲基胺;3-甲基氨哒嗪;

英文别名：

Pyridazin-3-ylmethanamine;3-Aminomethylpyridazine;3-Pyridazinemethanamine;ISOQUINOLINE-5-CARBOXALDEHYDE;3-PYRIDAZINYLMETHYLAMINE;(pyridazin-3-yl)methanamine;(Pyridazin-3-yl)methylamine;3-pyridazinylmethanamine;(pyridazin-3-ylmethyl)amine;1-(Pyridazin-3-yl)methanamine;BCPGZEVUJXKIHK-UHFFFAOYSA-N;BCP04627;3-Aminomethylpyridazine, AldrichCPR;5795AC;PB29341;ST1130879;AB1011610;3-(Aminomethyl)pyridazine;[(Pyridazin-3-yl)methyl]amine;F2147-1583;MFCD05664656;SCHEMBL245236;DB-028578;BS-12961;P15536;J-511695;CHEMBL4553514;93319-65-4;EN300-179791;CS-W006277;AKOS006292177;DTXSID00627216;Z1198165902;SY019901;

标识符

MDL：

MFCD05664656

InChIKey：

BCPGZEVUJXKIHK-UHFFFAOYSA-N

Inchi：

1S/C5H7N3/c6-4-5-2-1-3-7-8-5/h1-3H,4,6H2

SMILES：

N1C=CC=C(CN)N=1

3-哒嗪甲胺(93319-65-4)物化性质

实验特性

LogP : 0.63560
PSA : 51.80000
沸点 : 290.5℃ at 760 mmHg

计算特性

精确分子量 : 109.06400
氢键供体数量 : 1
氢键受体数量 : 3
可旋转化学键数量 : 1
同位素质量 : 109.063997236g/mol
重原子数量 : 8
复杂度 : 64.7
同位素原子数量 : 0
确定原子立构中心数量 : 0
不确定原子立构中心数量 : 0
确定化学键立构中心数量 : 0
不确定化学键立构中心数量 : 0
共价键单元数量 : 1
疏水参数计算参考值（XlogP） : -1.9
拓扑分子极性表面积 : 51.8

3-哒嗪甲胺(93319-65-4)安全信息

3-哒嗪甲胺(93319-65-4)海关数据

海关编码：

2933990090

海关数据：

中国海关编码：

2933990090

概述：

2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

申报要素：

品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

Summary：

2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

3-哒嗪甲胺(93319-65-4)推荐厂家更多厂家(34)

公司名称	手机号/电话	联系人	QQ	询单
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山东玖玥生物科技有限公司	15553333686	张文杰	643971	询单
湖北摆渡化学有限公司	13517219350 13517219350	彭星	1400878899	询单
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湖北拓邦化工有限公司	15102763473 027-59106185	涂梦婷	1400868822/1248089955	询单
湖北信康药化有限公司化学研究所	18827031272 027-59308705	肖经理	1438980011	询单
上海瀚思化工有限公司	18939883912 021-34536277	顾经理	3003949364	询单
湖北永阔科技有限公司	18771920143 027-59223108	郭经理	1248580055	询单

3-哒嗪甲胺(93319-65-4)合成路线

合成路线：1 步

52348-44-4

_100%

93319-65-4

反应条件：

1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Ethanol ; 1 h, rt

参考文献：

Synthesis and structure-activity relationships of amide derivatives of (4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ylidene)acetic acid as selective arginine vasopressin V2 receptor agonists

Tsukamoto, Issei; Koshio, Hiroyuki; Kuramochi, Takahiro; Saitoh, Chikashi; Yanai-Inamura, Hiroko; et al, Bioorganic & Medicinal Chemistry, 2009, 17(8), 3130-3141

合成路线：1 步

1279818-63-1

93319-65-4

反应条件：

1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Ethanol ; overnight, rt

参考文献：

Preparation of purinamine compounds treatment of neurodegenerative and mitochondrial disease

, World Intellectual Property Organization, , ,

合成路线：1 步

1072806-50-8

93319-65-4

反应条件：

1.1 Reagents: Sodium hydroxide Solvents: Water ; 1 h, reflux; reflux → rt

参考文献：

Heterocyclic compounds as stearoyl-CoA desaturase inhibitors and their preparation, pharmaceutical compositions and use in the treatment of diseases

, World Intellectual Property Organization, , ,

合成路线：1 步

53896-49-4

93319-65-4

反应条件：

1.1 Reagents: Hydrogen , Ammonia Catalysts: Nickel Solvents: Methanol ; 60 psi, 40 °C

参考文献：

Preparation of arylsulfonyl-substituted indoles as CB1 receptor modulators

, World Intellectual Property Organization, , ,

合成路线：1 步

93319-65-4

参考文献：

Preparation of indoylmethanamine derivatives and analogs for use as lysyl oxidase-like 2 inhibitors

, World Intellectual Property Organization, , ,

合成路线：1 步

93319-65-4

参考文献：

(Pyridylaminoalkylamino)thiadiazoles as histamine H1 antagonists

, European Patent Organization, , ,

3-哒嗪甲胺(93319-65-4) MSDS

基础信息

Name:	3-Pyridazinylmethylamine 97% Material Safety Data Sheet
Synonym:
CAS:	93319-65-4

Section 1 - Chemical Product ? MSDS Name:3-Pyridazinylmethylamine 97% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
93319-65-4	3-Pyridazinylmethylamine	97%	unlisted

Hazard Symbols: C
Risk Phrases: 34

Section 3 - HAZARDS IDENTIFICATION
? EMERGENCY OVERVIEW
Causes burns.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns.
Ingestion:
Causes gastrointestinal tract burns.
Inhalation:
Causes chemical burns to the respiratory tract.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
? Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
? General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use foam, dry chemical, or carbon dioxide.

Section 6 - ACCIDENTAL RELEASE MEASURES
? General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
? Handling:
Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.
Storage:
Store in a cool, dry place. Store in a tightly closed container.
Corrosives area.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
? Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 93319-65-4: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
?
Physical State: Solid or liquid
Color: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C5H7N3
Molecular Weight: 109.13

Section 10 - STABILITY AND REACTIVITY
? Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
? RTECS#:
CAS# 93319-65-4 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
3-Pyridazinylmethylamine - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION
?

Section 13 - DISPOSAL CONSIDERATIONS
? Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
?
IATA
Shipping Name: AMINES, SOLID, CORROSIVE, N.O.S.*
Hazard Class: 8
UN Number: 3259
Packing Group: III
IMO
Shipping Name: POLYAMINES, SOLID, CORROSIVE, N.O.S.
Hazard Class: 8
UN Number: 3259
Packing Group: III
RID/ADR
Shipping Name: POLYAMINES, SOLID, CORROSIVE, N.O.S.
Hazard Class: 8
UN Number: 3259
Packing group: III

Section 15 - REGULATORY INFORMATION
?
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 34 Causes burns.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 93319-65-4: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 93319-65-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 93319-65-4 is not listed on the TSCA inventory.
It is for research and development use only.

SECTION 16 - ADDITIONAL INFORMATION
N/A