934542-76-4 (5-[3-(Ethylsulfonyl)phenyl]-4,8-dimethyl-9H-pyrido[2,3-b]indole-7 -carboxylic acid,5-[3-(ethylsulfonyl)phenyl]-4,8-dimethyl-9h-pyrido[2,3-b]indole-7 -carboxylic Acid)

快速询单

结构式：

5-[3-(Ethylsulfonyl)phenyl]-4,8-dimethyl-9H-pyrido[2,3-b]indole-7 -carboxylic acidMOL文件

CAS号：

934542-76-4

中文名称：

5-[3-(Ethylsulfonyl)phenyl]-4,8-dimethyl-9H-pyrido[2,3-b]indole-7 -carboxylic acid

英文名称：

5-[3-(ethylsulfonyl)phenyl]-4,8-dimethyl-9h-pyrido[2,3-b]indole-7 -carboxylic Acid

分子式：

C₂₂H₂₀N₂O₄S

分子量：

408.470204353333

5-[3-(Ethylsulfonyl)phenyl]-4,8-dimethyl-9H-pyrido[2,3-b]indole-7 -carboxylic acid(934542-76-4)名称与标识符

名称

中文别名：

5-(3-(乙基磺酰基)苯基)-4,8-二甲基-9h-吡啶并[2,3-b]吲哚-7-羧酸;

英文别名：

5-[3-(Ethylsulfonyl)phenyl]-4,8-dimethyl-9H-pyrido[2,3-b]indole-7 -carboxylic acid;SureCN725001;5-(3-(ethylsulfonyl)phenyl)-3,8-dimethyl-9H-pyrido[2,3-b]indole-7-carboxylicacid;5-[3-(Bromomethyl)phenyl]-3-methyl-1,2,4-oxadiazol;5-[3-(ethylsulfonyl)phenyl]-3,8-dimethyl-9H-pyrido[2,3-b]indole-7-carboxylic acid;PubChem23332;SBB101218;3-(3-Methyl-1,2,4-oxadiazol-5-yl)benzyl bromide;5-[3-(diethylaminomethyl)-1-octyl-1H-indol-5-yl]pyrimidin-2-amine;CTK3I6433;5-[3-(bromomethyl)phenyl]-3-methyl-1,2,4-oxadizole;5-(3-diethylaminomethyl-1-octyl-1H-indol-5-yl)pyrimidin-2-ylamine;5-(3-(ETHYLSULFONYL)PHENYL)-4,8-DIMETHYL-9H-PYRIDO[2,3-B]INDOLE-7-CARBOXYLIC ACID;5-[3-(Ethylsulfonyl)phenyl]-3,8-dimethyl-9H-pyrido[2,3-b]indole-7-carboxylic acid (ACI);

标识符

MDL：

MFCD32876807

InChIKey：

GYVKQSOJRVOTQA-UHFFFAOYSA-N

Inchi：

1S/C22H20N2O4S/c1-4-29(27,28)15-7-5-6-14(9-15)17-10-16(22(25)26)13(3)20-19(17)18-8-12(2)11-23-21(18)24-20/h5-11H,4H2,1-3H3,(H,23,24)(H,25,26)

SMILES：

O=C(C1C(C)=C2C(C3C(N2)=NC=C(C)C=3)=C(C2C=C(S(CC)(=O)=O)C=CC=2)C=1)O

5-[3-(Ethylsulfonyl)phenyl]-4,8-dimethyl-9H-pyrido[2,3-b]indole-7 -carboxylic acid(934542-76-4)物化性质

计算特性

氢键供体数量 : 2
氢键受体数量 : 6
可旋转化学键数量 : 4
重原子数量 : 29

5-[3-(Ethylsulfonyl)phenyl]-4,8-dimethyl-9H-pyrido[2,3-b]indole-7 -carboxylic acid(934542-76-4)推荐厂家更多厂家(3)

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上海源叶生物科技有限公司	15026964105 15026964105	汤思磊	2881489226	询单

5-[3-(Ethylsulfonyl)phenyl]-4,8-dimethyl-9H-pyrido[2,3-b]indole-7 -carboxylic acid(934542-76-4)合成路线

合成路线：1 步

934542-75-3

_100%

934542-76-4

反应条件：

1.1 Reagents: Sulfuric acid Solvents: Water ; 30 min, 120 °C; 120 °C → rt

参考文献：

Preparation of pyridoindoles as kinase inhibitors

, United States, , ,

合成路线：1 步

934542-75-3

64-19-7

_100%

934542-76-4

反应条件：

1.1 Reagents: Sulfuric acid Solvents: Water ; 30 min, 120 °C; 120 °C → rt
1.2 Solvents: Water ; cooled

参考文献：

Pyrido[2,3-b]indole derivatives as kinase inhibitors and their preparation and use in the treatment of diseases

, World Intellectual Property Organization, , ,

合成路线：1 步

934542-75-3

64-19-7

_100%

934542-76-4

反应条件：

1.1 Reagents: Sulfuric acid Solvents: Water ; 30 min, 120 °C; 120 °C → rt
1.2 Reagents: Water ; cooled

参考文献：

Polymorphs of 5-(3-(ethylsulfonyl)phenyl)-3,8-dimethyl-N-(1-methylpiperidin-4-yl)-9H-pyrido[2,3-b]indole-7-carboxamide for disease treatment

, World Intellectual Property Organization, , ,

合成路线：1 步

934542-75-3

_100%

934542-76-4

反应条件：

1.1 Reagents: Sulfuric acid Solvents: Water ; 30 min, 120 °C; 120 °C → rt; cooled

参考文献：

Preparation of pyridoindoles as kinase inhibiting compounds for treating and preventing kinase-associated diseases

, World Intellectual Property Organization, , ,

合成路线：1 步

1005498-28-1

_100%

934542-76-4

反应条件：

1.1 Reagents: Sodium hydroxide Solvents: Tetrahydrofuran , Dimethylacetamide , Water ; 3.5 h, reflux; reflux → rt
1.2 Reagents: Hydrochloric acid Solvents: Water ; pH 6 - 7, < 30 °C

参考文献：

Preparation of α-carbolines via palladium-catalyzed cyclization of diarylamines.

, World Intellectual Property Organization, , ,

合成路线：1 步

934542-75-3

_96%

934542-76-4

反应条件：

1.1 Reagents: Sulfuric acid ; 120 °C

参考文献：

Integrated Cross-Coupling Strategy for an α-Carboline-Based Aurora B Kinase Inhibitor

Mineno, Masahiro; Sera, Misayo; Ueda, Tsuyoshi; Mizufune, Hideya; Zanka, Atsuhiko; et al, Journal of Organic Chemistry, 2015, 80(3), 1564-1568

合成路线：1 步

1005497-83-5

845870-47-5

_92%

934542-76-4

反应条件：

1.1 Reagents: Sodium carbonate Catalysts: Tetrakis(triphenylphosphine)palladium Solvents: Dimethylacetamide , Water ; 2 h, 100 °C; 100 °C → 60 °C
1.2 Reagents: Sodium hydroxide Solvents: Water ; 1 h, 60 °C; 60 °C → rt
1.3 Reagents: Hydrochloric acid Solvents: Water ; 30 min, pH 5 - 6, rt

参考文献：

Integrated Pd-catalyzed cross-coupling strategies for furnishing α-carbolines

Sera, Misayo; Mizufune, Hideya; Ueda, Tsuyoshi; Mineno, Masahiro; Zanka, Atsuhiko, Tetrahedron, 2017, 73(40), 5946-5958

合成路线：1 步

934542-76-4

参考文献：

Polymorphs of 5-(3-(ethylsulfonyl)phenyl)-3,8-dimethyl-n-(1-methylpiperidin-4-yl)-9h-pyrido[2,3-b]indole-7-carboxamide and methods of use therefor

, United States, , ,

合成路线：1 步

934542-76-4

参考文献：

Polymorphs of hydrochloride salt of 5-(3-(ethylsulfonyl)phenyl)-3,8-dimethyl-N-(1-methylpiperidin-4-yl)-9H-pyrido[2,3-b]indole-7-carboxamide to treat a diseases involving kinase activity

, World Intellectual Property Organization, , ,

合成路线：1 步

934542-76-4

参考文献：

Preparation of pyridoindoles as kinase inhibiting compounds for treating and preventing kinase-associated diseases

, World Intellectual Property Organization, , ,

80775-42-4(1-(5-溴噻吩-2-基)-3-氯丙烷-1-酮) 81462-07-9(4-phenyloxan-4-ol) 81562-78-9(八氢异喹啉-4alpha-醇) 81574-69-8(2-溴-4,6-二甲氧基苯甲醛) 81560-06-7(5-溴-3-甲基-2-(甲基硫代)嘧啶-4(3H)-酮) 81568-09-4(5-Chloro-2-dimethylaminopyrimidine) 816448-94-9(6-METHYLQUINOLINE-4-CARBOXYLIC ACID) 81540-86-5((8Z,11Z,14Z)-(8,9,11,12,14,15-2H6)-8,11,14-Icosatrienoic acid)

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问答

求5-(3-(ethylsulfonyl)phenyl)-4,8-diMethyl-9H-pyrido[2,3-b]indole-7-carboxylic acid 934542-76-4的供应商

960化工网为您提供5-[3-(Ethylsulfonyl)phenyl]-4,8-dimethyl-9H-pyrido[2,3-b]indole-7 -carboxylic acid专业化合物百科信息，包括中文名，英文名，分子式，分子量，以及该化合物的CasNo.934542-76-4,相关理化性质;并提供了优质生产厂家信息包括厂家名称和联系方式等。 WAP版:934542-76-4 国际站:934542-76-4

934542-76-4 (5-[3-(Ethylsulfonyl)phenyl]-4,8-dimethyl-9H-pyrido[2,3-b]indole-7 -carboxylic acid,5-[3-(ethylsulfonyl)phenyl]-4,8-dimethyl-9h-pyrido[2,3-b]indole-7 -carboxylic Acid)

5-[3-(Ethylsulfonyl)phenyl]-4,8-dimethyl-9H-pyrido[2,3-b]indole-7 -carboxylic acid(934542-76-4)名称与标识符

名称

标识符

5-[3-(Ethylsulfonyl)phenyl]-4,8-dimethyl-9H-pyrido[2,3-b]indole-7 -carboxylic acid(934542-76-4)物化性质

计算特性

5-[3-(Ethylsulfonyl)phenyl]-4,8-dimethyl-9H-pyrido[2,3-b]indole-7 -carboxylic acid(934542-76-4)推荐厂家 更多厂家(3)

5-[3-(Ethylsulfonyl)phenyl]-4,8-dimethyl-9H-pyrido[2,3-b]indole-7 -carboxylic acid(934542-76-4)合成路线

目录

5-[3-(Ethylsulfonyl)phenyl]-4,8-dimethyl-9H-pyrido[2,3-b]indole-7 -carboxylic acid(934542-76-4)推荐厂家更多厂家(3)