935-92-2 (2,3,5-三甲基苯醌,2,3,5-trimethylcyclohexa-2,5-diene-1,4-dione)

_100%

反应条件：

1.1 Reagents: Hydrogen peroxide Solvents: Acetic acid

参考文献：

A convenient synthesis of alkyl-substituted p-benzoquinones from phenols by a hydrogen peroxide/heteropoly acid system

Shimizu, Masao; Orita, Hideo; Hayakawa, Takashi; Takehira, Katsuomi, Tetrahedron Letters, 1989, 30(4), 471-4

合成路线：1 步

91060-95-6

_100%

反应条件：

1.1 Reagents: Sulfuric acid , Water Solvents: Methanol , Acetonitrile ; 0 °C

参考文献：

Direct Anodic Conversion of 4-Hydroxybenzaldehydes into Benzoquinones

Sprang, Fiona; Klein, Jana; Waldvogel, Siegfried R., ACS Sustainable Chemistry & Engineering, 2023, 11(20), 7755-7764

合成路线：1 步

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反应条件：

1.1 Reagents: Oxygen Catalysts: 2951861-94-0 Solvents: Acetonitrile ; 5 h, 5 atm, 40 °C

参考文献：

Preparation of 2,3,5-trimethylcyclohexa-2,5-diene-1,4-dione

, China, , ,

合成路线：1 步

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反应条件：

1.1 Reagents: Oxygen Catalysts: 2876909-00-9 Solvents: Dichloromethane-d2 ; -196 °C; 20 min, -20 °C

参考文献：

A Copper Cage-Complex as Mimic of the pMMO CuC Site

Bete, Sarah C.; May, Leander K.; Woite, Philipp; Roemelt, Michael; Otte, Matthias, Angewandte Chemie, 2022, 61(35),

合成路线：1 步

26998-80-1

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反应条件：

1.1 Reagents: Oxygen Catalysts: Iron Solvents: Acetonitrile ; 5 h, 50 °C

参考文献：

Preparation of 2,3,5-trimethyl-1,4-benzoquinone by oxygen oxidation

, China, , ,

合成路线：1 步

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反应条件：

1.1 Reagents: Hydrogen peroxide Catalysts: 1-Butanaminium, N,N,N-tributyl-, μ-hydroxy(octadeca-μ-oxodecaoxodecatungstate)pe… Solvents: Acetonitrile , Water ; 15 min, 60 °C

参考文献：

H2O2-based selective oxidations by divanadium-substituted polyoxotungstate supported on nitrogen-doped carbon nanomaterials

Evtushok, Vasiliy Yu. ; Podyacheva, Olga Yu.; Suboch, Arina N.; Maksimchuk, Nataliya V. ; Stonkus, Olga A. ; et al, Catalysis Today, 2020, 354, 196-203

合成路线：1 步

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反应条件：

1.1 Reagents: Iodobenzene diacetate (polystyrene supported) Solvents: Methanol ; 2 - 4 h, rt

参考文献：

Poly[4-(diacetoxyiodo)styrene]

Taylor, Richard J. K.; Addie, Matthew S., e-EROS Encyclopedia of Reagents for Organic Synthesis, 2002, 1, 1-4

合成路线：1 步

_100%

反应条件：

1.1 Reagents: Hydrogen peroxide Catalysts: Titanium Solvents: Acetonitrile ; 10 min, 80 °C

参考文献：

Environmentally Benign Oxidation of Alkylphenols to p-Benzoquinones: A Comparative Study of Various Ti-Containing Catalysts

Kholdeeva, Oxana A.; Ivanchikova, Irina D.; Maksimchuk, Nataliya V.; Mel'gunov, Maxim S.; Chang, Jong-San; et al, Topics in Catalysis, 2014, 57(17-20), 1377-1384

合成路线：1 步

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反应条件：

1.1 Reagents: Hydrogen peroxide Catalysts: Zirconium dioxide , Copper ; 30 min, rt

参考文献：

Cu2+-containing composites based on zirconia and powdered cellulose: effect of surface charge on their complexation and catalytic properties

Kovaleva, E. G.; Molochnikov, L. S.; Parshina, E. V.; Shishmakov, A. B.; Mikushina, Yu. V.; et al, Khimicheskaya Fizika, 2014, 33(6), 27-36

合成路线：1 步

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反应条件：

1.1 Reagents: Oxygen Solvents: 1-Hexanol , Water ; 20 min, 60 °C

参考文献：

Trimethyl-1,4-benzoquinone synthesis via 2,3,6-trimethylphenol catalytic oxidation by oxygen in the presence of non-Keggin-type Mo-V-phosphoric heteropoly acid solutions

Rodikova, Yulia Anatolievna; Zhizhina, Elena Georgievna, Journal of Chemistry and Chemical Engineering, 2013, 7(9), 808-820

合成路线：1 步

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反应条件：

1.1 Reagents: tert-Butyl hydroperoxide Catalysts: Cryptomelane (K(Mn8O16)) Solvents: Acetonitrile ; 4 h, 80 °C

参考文献：

Microwave-Assisted Synthesis of Manganese Oxide Octahedral Molecular Sieve (OMS-2) Nanomaterials under Continuous Flow Conditions

Opembe, Naftali N.; King'ondu, Cecil K.; Espinal, Anais E.; Chen, Chun-Hu; Nyutu, Edward K.; et al, Journal of Physical Chemistry C, 2010, 114(34), 14417-14426

合成路线：1 步

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反应条件：

1.1 Reagents: Hydrogen peroxide Catalysts: Ferrous sulfate Solvents: Water ; 3 h, 45 °C

参考文献：

An efficient catalytic oxidation of o-methylphenols with the Fenton's reagent

Li, Y.; Zhang, P.; Wu, M.; Liu, W.; Yi, Zh.; et al, Oxidation Communications, 2008, 31(3), 672-676

合成路线：1 步

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反应条件：

1.1 Reagents: Hydrogen peroxide Catalysts: Titanocene dichloride , Titanium , Silica Solvents: Acetonitrile ; 30 min, 80 °C

参考文献：

Highly Selective Oxidation of Alkylphenols to Benzoquinones with Hydrogen Peroxide over Silica-Supported Titanium Catalysts: Titanium Cluster Site versus Titanium Single Site

Kholdeeva, Oxana A.; Ivanchikova, Irina D.; Guidotti, Matteo; Pirovano, Claudio; Ravasio, Nicoletta; et al, Advanced Synthesis & Catalysis, 2009, 351, 1877-1889

合成路线：1 步

_100%

反应条件：

1.1 Reagents: Iodobenzene diacetate Solvents: Methanol

参考文献：

Oxidation of phenolic compounds with organohypervalent iodine reagents

Moriarty, Robert M.; Prakash, Om, Organic Reactions (Hoboken, 2001, 57,

合成路线：1 步

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反应条件：

1.1 Reagents: Potassium peroxymonosulfate Catalysts: Sodium (SP-4-1)-[29H,31H-phthalocyanine-2,9,16,23-tetrasulfonato(6-)-κN29,κN30,κ… Solvents: Methanol , Water ; 5 min, rt

参考文献：

Oxidation of 2,3,6-trimethylphenol with potassium peroxymonosulfate catalyzed by iron and cobalt phthalocyanine tetrasulfonates in a methanol-water mixture

Cimen, Yasemin; Tuerk, Hayrettin, Applied Catalysis, 2008, 340(1), 52-58

合成路线：1 步

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反应条件：

1.1 Reagents: Iodine, bis(acetato-κO)[4-[(methylamino)carbonyl]phenyl]- (polystyrene-supported) Solvents: Methanol

参考文献：

Development of new and efficient polymer-supported hypervalent iodine reagents

Ficht, S.; Mulbaier, M.; Giannis, A., Tetrahedron, 2001, 57(23), 4863-4866

合成路线：1 步