94-60-0 (1,4-环己基二甲酸二甲酯,Dimethyl Cyclohexane-1,4-dicarboxylate(1,4-Cyclohexanedicarboxylic Dimethyl Ester))

_100%

反应条件：

1.1 Reagents: Hydrogen Catalysts: Ruthenium , Carbon Solvents: Tetrahydrofuran ; 6 h, 120 °C; 45 bar

参考文献：

Zinc(II) acetate Catalyzed Depolymerization of Poly(ethylene terephthalate)

Hofmann, Melanie; Sundermeier, Jannis; Alberti, Christoph; Enthaler, Stephan, ChemistrySelect, 2020, 5(32), 10010-10014

合成路线：1 步

74-88-4

_100%

反应条件：

1.1 Reagents: Potassium carbonate Solvents: Dimethylformamide ; overnight, rt

参考文献：

Structure-Activity Relationships of Cycloalkylamide Derivatives as Inhibitors of the Soluble Epoxide Hydrolase

Kim, In-Hae; Park, Yong-Kyu; Hammock, Bruce D.; Nishi, Kosuke, Journal of Medicinal Chemistry, 2011, 54(6), 1752-1761

合成路线：1 步

_100%

反应条件：

1.1 Reagents: Hydrogen Catalysts: Alumina , Ruthenium Solvents: Methanol ; 1 h, 5 MPa, 140 °C

参考文献：

Preparation of dimethyl 1,4-cyclohexanedicarboxylate

, China, , ,

合成路线：1 步

_99%

反应条件：

1.1 Reagents: Hydrogen ; 6 MPa, 140 °C

参考文献：

Preparation of 1,4-cyclohexanedicarboxylic acid dimethyl ester

, China, , ,

合成路线：1 步

_99%

反应条件：

1.1 Reagents: Hydrogen Catalysts: Platinum ; 10 h, 5 MPa, 413 K

参考文献：

Synthesis of gasoline and jet fuel range cycloalkanes and aromatics from poly(ethylene terephthalate) waste

Tang, Hao; Li, Ning; Li, Guangyi; Wang, Aiqin; Cong, Yu; et al, Green Chemistry, 2019, 21(10), 2709-2719

合成路线：1 步

_99%

反应条件：

1.1 Reagents: Hydrogen Catalysts: Alumina , Ruthenium Solvents: Ethyl acetate ; 20 h, 700 - 800 psi, 120 °C

参考文献：

Hydrogenation process and preparation of a highly stable catalyst for the manufacture of dimethyl 1,4-cyclohexanedicarboxylate from dimethyl terephthalate

, United States, , ,

合成路线：1 步

_98%

反应条件：

1.1 Reagents: Hydrogen Catalysts: Lanthanum sesquioxide ; 3 MPa, 140 °C

参考文献：

Hydrogenation catalyst for hydrogenation of benzene-carboxylic acid alkyl ester and preparation method thereof

, China, , ,

合成路线：1 步

_97%

反应条件：

1.1 Reagents: Hydrogen Catalysts: Ruthenium ; 4.5 h, 5 MPa, 150 °C

参考文献：

Method of manufacturing batch hydrogenation reduction compounds

, Japan, , ,

合成路线：1 步

67-56-1

_97%

反应条件：

1.1 Reagents: Hydrochloric acid , Thionyl chloride Solvents: Methanol ; cooled; 1 h, reflux

参考文献：

Preparation of hydroxamic acid derivatives useful in the treatment of bacterial infections

, World Intellectual Property Organization, , ,

合成路线：1 步

_94%

反应条件：

1.1 Reagents: Hydrogen Catalysts: Platinum Solvents: Acetic acid

参考文献：

Electrolytic synthesis of the dimethyl ester of [1,1'-bicyclohexane]-4,4'-dicarboxylic acid from trans-hexahydroterephthalic acid monomethyl ester

Fichter, Fr.; Holbro, Theodor, Helvetica Chimica Acta, 1938, 21, 141-51

合成路线：1 步

1257982-57-2

_92%

反应条件：

1.1 Reagents: Hydrogen Catalysts: Platinum ; 250 °C

参考文献：

Solvent-driven isomerization of cis,cis-muconic acid for the production of specialty and performance-advantaged cyclic biobased monomers

Carraher, Jack M.; Carter, Prerana; Rao, Radhika G.; Forrester, Michael J.; Pfennig, Toni; et al, Green Chemistry, 2020, 22(19), 6444-6454

合成路线：1 步

_92%

反应条件：

1.1 Reagents: Sodium hydroxide , Sodium borohydride Catalysts: Alumina , Palladium alloy, nonbase, Pd,Ru Solvents: Water ; pH 8, rt; 20 min
1.2 6 h, 8 MPa, 160 °C

参考文献：

Low-content supported ruthenium-palladium bimetal hydrogenation catalyst and preparation method thereof

, China, , ,

合成路线：1 步

67-56-1

_91%

反应条件：

1.1 Reagents: Sulfuryl chloride Solvents: Methanol ; 0 °C; overnight, rt

参考文献：

Preparation of substituted diaminocarboxamide and diaminocarbonitrile pyrimidines as JNK pathway inhibitors

, World Intellectual Property Organization, , ,

合成路线：1 步

_90%

反应条件：

1.1 Reagents: Hydrogen Catalysts: Alumina , Ruthenium Solvents: Water ; 4 h, 300 °C

参考文献：

Selective hydrogenation of dimethyl terephthalate on Ru-based catalysts in the fixed bed reactor

Zhang, Jia; Zhou, Jiande; Shen, Weihua; Zhu, Zhiqing; Fang, Yunjin, Shiyou Huagong, 2020, 49(6), 521-528

合成路线：1 步

_85%

反应条件：

1.1 Reagents: Hydrogen Catalysts: Palladium , Ruthenium Solvents: Ethyl acetate ; 6 h, 8 MPa, 180 °C

参考文献：

Composition regulation of bimetallic RuPd catalysts supported on porous alumina spheres for selective hydrogenation

Chen, Jiali; Liu, Xin; Zhang, Fazhi, Chemical Engineering Journal (Amsterdam, 2015, 259, 43-52

合成路线：1 步

67-56-1

_83%

反应条件：

1.1 Catalysts: Sulfuric acid Solvents: Methanol ; 5 h, 75 °C

参考文献：

Thermoreversible gelation of poly(urethane acyl-semicarbazides) carrying cycloaliphatic moieties and studies on selective adsorption of dyes from wastewater

Baddi, Sravan; Palanisamy, Aruna, European Polymer Journal, 2018, 99, 90-101

合成路线：1 步

_81%

反应条件：

1.1 Reagents: Hydrogen

参考文献：

Dimethyl cis- and trans-1,4-cyclohexanedicarboxylates

Naumann, Hans Joachim; Schmidt, Harald, Journal fuer Praktische Chemie (Leipzig), 1965, 29(3-6), 230-6

合成路线：1 步

_37%

反应条件：

1.1 Reagents: Hydrogen Catalysts: Dibromo[1,2-di(methoxy-κO)ethane]nickel ; 100 bar, rt; 42 h, 160 °C

参考文献：

Metal oxide-supported earth-abundant metal catalysts for highly efficient organic transformations

, World Intellectual Property Organization, , ,

合成路线：1 步

_10%