950846-89-6 (N-氨乙基-罗丹明B酰亚胺,2-(2-Aminoethyl)-3',6'-bis(diethylamino)spiroisoindoline-1,9'-xanthen-3-one (>80%))

_99%

反应条件：

1.1 Solvents: Ethanol ; rt; 16 h, rt → reflux

参考文献：

Fluorophore ATCUN complexes: combining agent and probe for oxidative DNA cleavage

Wende, C.; Kulak, N., Chemical Communications (Cambridge, 2015, 51(62), 12395-12398

合成路线：1 步

_96%

反应条件：

1.1 Solvents: Ethanol ; rt; 24 h, reflux

参考文献：

Chemically-modified cellulose paper as smart sensor device for colorimetric and optical detection of hydrogen sulfate in water

Rull-Barrull, Jordi; d'Halluin, Martin; Le Grognec, Erwan; Felpin, Francois-Xavier, Chemical Communications (Cambridge, 2016, 52(12), 2525-2528

合成路线：1 步

_95%

反应条件：

1.1 24 h, reflux

参考文献：

A Single Enzyme Mediates the "Quasi-Living" Formation of Multiblock Copolymers with a Broad Biomedical Potential

Scheibel, Dieter Michael; Guo, Dandan; Luo, Juntao ; Gitsov, Ivan, Biomacromolecules, 2020, 21(6), 2132-2146

合成路线：1 步

_95%

反应条件：

1.1 Solvents: Ethanol ; 12 h, 80 °C

参考文献：

Rhodamine B-based GSH sensor, preparation method and application thereof

, China, , ,

合成路线：1 步

_95%

反应条件：

1.1 Solvents: Ethanol ; 12 h, reflux

参考文献：

Synthesis and evaluation of a novel fluorescent chemosensor for glutathione based on a rhodamine B and N-[4-(carbonyl) phenyl]maleimide conjugate and its application in living cell imaging

Shu, Hai; Wu, Xiaolei; Zhou, Baojing; Han, Yingbin; Jin, Mingjie; et al, Dyes and Pigments, 2017, 136, 535-542

合成路线：1 步

509-34-2

_95%

反应条件：

1.1 Solvents: Ethanol ; 48 h, reflux

参考文献：

Rhodamine based derivative and its zinc complex: synthesis and recognition behavior toward Hg(II)

Zhou, Xin; Yan, Wei; Zhao, Tong; Tian, Zhexi; Wu, Xue, Tetrahedron, 2013, 69(46), 9535-9539

合成路线：1 步

_93%

反应条件：

1.1 Solvents: Ethanol ; rt; rt → 80 °C; 10 h, 80 °C

参考文献：

Preparation of mercury ion fluorescence sensor based on rhodamine B and application in mercury ion detection

, China, , ,

合成路线：1 步

4344-42-7

_93%

反应条件：

1.1 Solvents: Methanol ; rt; 24 h, reflux
1.2 Reagents: Hydrochloric acid Solvents: Water ; rt
1.3 Reagents: Sodium hydroxide Solvents: Water ; pH 8 - 9, rt

参考文献：

Nonstoichiometric copper chalcogenides for photo-activated alkyne/azide cycloaddition

Zou, Hong Yan; Gao, Ming Xuan; Yang, Tong; Zeng, Qiao Ling; Yang, Xiao Xi; et al, Physical Chemistry Chemical Physics, 2017, 19(10), 6964-6968

合成路线：1 步

_93%

反应条件：

1.1 Solvents: Ethanol ; 7 h, reflux

参考文献：

A ratiometric fluorescent probe for determining Pd2+ ions based on coordination

Qiao, Bo; Sun, Shiguo; Jiang, Na; Zhang, Si; Peng, Xiaojun, Dalton Transactions, 2014, 43(12), 4626-4630

合成路线：1 步

_93%

反应条件：

1.1 Solvents: Ethanol ; 7 h, reflux

参考文献：

Naphthylamine-Rhodamine-Based Ratiometric Fluorescent Probe for the Determination of Pd2+ Ions

Sun, Shiguo; Qiao, Bo; Jiang, Na; Wang, Jitao; Zhang, Si; et al, Organic Letters, 2014, 16(4), 1132-1135

合成路线：1 步

_92%

反应条件：

1.1 Solvents: Ethanol ; rt; rt → 80 °C; 12 h, 80 °C

参考文献：

Preparation and application of rhodamine B-based Fe3+ fluorescence sensor based on 1-naphthoyl chloride

, China, , ,

合成路线：1 步

_92%

反应条件：

1.1 Solvents: Ethanol ; 12 h, reflux

参考文献：

Reversible "turn-off-on" fluorescence response of Fe(III) towards Rhodamine B based probe in vivo and plant tissues

Song, Fan; Shao, Xiaotao; Zhu, Jing; Bao, Xiaofeng; Du, Lei; et al, Tetrahedron Letters, 2019, 60(20), 1363-1369

合成路线：1 步

_92%

反应条件：

1.1 Solvents: Ethanol ; 12 h, reflux

参考文献：

A reversible "turn-off-on" fluorescent probe for real-time visualization of mercury(II) in environmental samples and its biological applications

Song, Fan; Yang, Chao; Shao, Xiaotao; Du, Lei; Zhu, Jing; et al, Dyes and Pigments, 2019, 165, 444-450

合成路线：1 步

3375-25-5

_92%

反应条件：

1.1 Solvents: Ethanol ; 12 h, reflux

参考文献：

Dual-binding pyridine and rhodamine B conjugate derivatives as fluorescent chemosensors for ferric ions in aqueous media and living cells

Song, Fan; Yang, Chao; Liu, Haibo; Gao, Zhigang; Zhu, Jing; et al, Analyst (Cambridge, 2019, 144(9), 3094-3102

合成路线：1 步

4344-42-7

_92%

反应条件：

1.1 Solvents: Ethanol ; rt → 80 °C; 12 h, 80 °C

参考文献：

Preparation and application of rhodamine B light-emitting material based on 2,6-pyridine dicarbonyl chloride

, China, , ,

合成路线：1 步

_92%

反应条件：

1.1 Solvents: Ethanol ; rt; rt → 80 °C; 12 h, 80 °C

参考文献：

Preparation method of pyridine-3-sulfonyl chloride-based rhodamine B-type Hg2+ fluorescent sensor and its application

, China, , ,

合成路线：1 步

_92%

反应条件：

1.1 Solvents: Ethanol ; rt; rt → 80 °C; 12 h, 80 °C

参考文献：

Preparation of Rhodamine B ethylenediamine 2-pyridine carboxylic acid derivative useful as fluorescent probe useful for the detection of Fe3+

, China, , ,

合成路线：1 步

_92%