95-44-3 (L-苏阿糖,L-Threose)

快速询单

结构式：

L-苏阿糖MOL文件

CAS号：

95-44-3

中文名称：

L-苏阿糖

英文名称：

L-Threose

分子式：

C₄H₈O₄

分子量：

120.103921890259

简介：

(2R,3S)-2,3,4-Trihydroxybutanal 是一种生化试剂，可作为生物材料或有机化合物，用于生命科学相关研究。

L-苏阿糖(95-44-3)名称与标识符

名称

中文别名：

L-苏糖;L-(＋)-苏糖;L-苏阿糖;

英文别名：

L-(+)-Threose;(2R,3S)-2,3,4-Trihydroxybutanal;Butanal,2,3,4-trihydroxy-, (2R,3S)-;L -(+)-THREOSE SYRUP;L-Threose;L-Threose (~0.2 M in Water);DL-Erythrose;L-Threofuranose;L-threo-tetrose;Threose;Threose,L;UNII-MHH79K1BVR;(2R,3S)-2,3,4-Trihydroxybutanal (ACI);Butanal, 2,3,4-trihydroxy-, [R-(R*,S*)]- (ZCI);Threose, L- (8CI);L;HY-W040288;95-44-3;Q27109399;l(+)-threose;EINECS 202-419-6;F49E7756-40E6-4325-AABD-CAE8087B66F9;CHEBI:21405;SCHEMBL117909;Threose, L-;CS-W021028;GEO-04659;MHH79K1BVR;J-200002;DTXSID601017426;(2R,3S)-2,3,4-Trihydroxy-butanal; [R-(R*,S*)]-2,3,4-Trihydroxy-butanal; L-Threofuranose;DTXSID40915184;L-THREOSE [MI];YTBSYETUWUMLBZ-IMJSIDKUSA-N;AKOS016844121;

标识符

MDL：

24900465

InChIKey：

YTBSYETUWUMLBZ-IMJSIDKUSA-N

Inchi：

1S/C4H8O4/c5-1-3(7)4(8)2-6/h1,3-4,6-8H,2H2/t3-,4-/m0/s1

SMILES：

[C@H](O)(CO)[C@@H](O)C=O

L-苏阿糖(95-44-3)物化性质

实验特性

LogP : -1.94320
PSA : 69.92000
折射率 : 1.619
沸点 : 290.6°Cat760mmHg
熔点 : 162-163 ºC
闪点 : 129.5°C
溶解度 : 易溶 (872 g/L) (25 ºC),
颜色与性状 : 糖浆
比旋光度 : D20 +13.2° (c = 4.5)
密度 : 1.410±0.06 g/cm3 (20 ºC 760 Torr),

计算特性

精确分子量 : 120.04200
氢键供体数量 : 3
氢键受体数量 : 4
可旋转化学键数量 : 0
同位素质量 : 120.042
重原子数量 : 8
复杂度 : 72.4
同位素原子数量 : 0
确定原子立构中心数量 : 2
不确定原子立构中心数量 : 0
确定化学键立构中心数量 : 0
不确定化学键立构中心数量 : 0
共价键单元数量 : 1
疏水参数计算参考值（XlogP） : -2.2
拓扑分子极性表面积 : 77.8A^2

L-苏阿糖(95-44-3)安全信息

WGK Germany： 3
储存条件： 2-8°C

L-苏阿糖(95-44-3)国际标准相关数据

EINECS：

MFCD00066540

L-苏阿糖(95-44-3)海关数据

海关编码：

2912491000

海关数据：

中国海关编码：

2912491000

概述：

2912491000. 醛醇. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%

Summary：

2912491000. other aldehyde-alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

L-苏阿糖(95-44-3)推荐厂家更多厂家(27)

公司名称	手机号/电话	联系人	QQ	询单
上海维亦特生物科技有限公司	15317051735	赵静	2033721411	询单
上海甄准生物科技有限公司	13918293035 021-68920155	陈经理13918293035	3001005926	询单
上海源叶生物科技有限公司	15026964105 15026964105	汤思磊	2881489226	询单
上海惠诚生物科技有限公司	18018625233	文俊	2303607288	询单
江苏永健医药科技有限公司	17701422016	韩经理	3587493084	询单
湖北云镁科技有限公司	18327059871 027-59206672	方经理	235010015	询单
上海瀚思化工有限公司	18939883912 021-34536277	顾经理	3003949364	询单
金锦乐（湖南）化学有限公司		金锦乐	1226360695	询单
铼博（上海）生化科技有限公司	13311756052 021-60536361 13311756052 13311756131	张经理	2851717387	询单
赫澎（上海）生物科技有限公司	13122891558 186-16545970	张硕	3418426269	询单

L-苏阿糖(95-44-3)合成路线

合成路线：1 步

反应条件：

1.1 Catalysts: 2882064-88-0 (Zn-complexes) ; 2 h, rt

参考文献：

Mechano-catalysis boosts glycolaldehyde conversion to tetroses over a new Zn-COF catalyst

Yang, Junxia; Fang, Xu; Ren, Guoqing; Yu, Tie, New Journal of Chemistry, 2023, 47(2), 558-562

合成路线：1 步

34693-27-1

_99%

95-44-3

反应条件：

1.1 Reagents: Acetic acid Solvents: Water ; 4 h, reflux

参考文献：

Rhodium-Catalyzed Decarbonylation of Aldoses

Nygaard Monrad, Rune; Madsen, Robert, Journal of Organic Chemistry, 2007, 72(25), 9782-9785

合成路线：1 步

95140-39-9

_91%

95-44-3

反应条件：

1.1 Reagents: Ammonium hydroxide

参考文献：

The preparation of aldotetroses from aldopentoses via 1,1-diethylsulfonyl-3,4,5-trihydroxypent-1-enes

Hough, L.; Taylor, T. J., Journal of the Chemical Society, 1955, 1212, 1212-18

合成路线：1 步

537690-74-7

_90%

95-44-3

反应条件：

1.1 Reagents: Sodium methoxide Solvents: Methanol ; 4 h, 4 °C
1.2 Reagents: Amberlite IR 120 Solvents: Water
1.3 Solvents: Ethanol , Water

参考文献：

Chemistry of α-aminonitriles. 37. The α-L-threofuranosyl-(3'→2')-oligonucleotide system ("TNA"): Synthesis and pairing properties

Schoning, Kai-Uwe; Scholz, Peter; Wu, Xiaolin; Guntha, Sreenivasulu; Delgado, Guillermo; et al, Helvetica Chimica Acta, 2002, 85(12), 4111-4153

合成路线：1 步

4172-44-5

95-44-3

反应条件：

1.1 Reagents: Potassium hydroxide Solvents: Water ; 6.8 h, neutralized, 31 °C

参考文献：

Methods for the production of L-threonic acid salts from L-xylonic acid

, World Intellectual Property Organization, , ,

合成路线：1 步

72656-08-7

95-44-3

反应条件：

1.1 Reagents: Ferrous sulfate , Hydrogen peroxide Solvents: Water ; rt; rt → 80 °C

参考文献：

Preparation of calcium threonate

, China, , ,

合成路线：1 步

95-44-3

参考文献：

The production of threose as a degradation product from L-ascorbic acid

Lopez, Mercedes G.; Feather, Milton S., Journal of Carbohydrate Chemistry, 1992, 11(6), 799-806

合成路线：1 步

95-44-3

参考文献：

Oxidation of carbohydrate derivatives with silver carbonate on Celite. IV. Oxidation of L-sorbose, an alternative synthesis of L-threose

Morgenlie, Svein, Acta Chemica Scandinavica (1947-1973), 1972, 26(5), 2146-7

合成路线：1 步

141-46-8

95-44-3

583-50-6

反应条件：

1.1 Catalysts: Quinidine Solvents: Chloroform ; 3 d, rt

参考文献：

Tertiary Amine Promoted Asymmetric -Aldol Reaction of Aldehydes

Gut, Bartosz; Mlynarski, Jacek, European Journal of Organic Chemistry, 2015, 2015(23), 5075-5078

合成路线：1 步

反应条件：

1.1 Solvents: Water ; 48 h, rt

参考文献：

Catalytic Gels for a Prebiotically Relevant Asymmetric Aldol Reaction in Water: From Organocatalyst Design to Hydrogel Discovery and Back Again

Hawkins, Kirsten; Patterson, Anna K.; Clarke, Paul A.; Smith, David K., Journal of the American Chemical Society, 2020, 142(9), 4379-4389

合成路线：1 步

反应条件：

1.1 Catalysts: Platinum , Titania Solvents: Water ; 25 °C

参考文献：

Method for producing high-purity rare sugar from sugar alcohol through photocatalytic reaction using titania

, Japan, , ,

L-苏阿糖(95-44-3)参考资料

Beilstein：

202-419-6

PubChem CID：

24900465

L-苏阿糖(95-44-3) MSDS

基础信息

Name:	L(+)-Threose Material Safety Data Sheet
Synonym:
CAS:	95-44-3

Section 1 - Chemical Product ? MSDS Name:L(+)-Threose Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
95-44-3	L(+)-Threose		202-419-6

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
? EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
? Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
? General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
? General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container.

Section 7 - HANDLING and STORAGE
? Handling:
Use with adequate ventilation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.
Deep freeze (below -20C).

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
? Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 95-44-3: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
?
Physical State: Viscous liquid
Color: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: 162 deg C
Solubility in water: Soluble.
Specific Gravity/Density:
Molecular Formula: C4H8O4
Molecular Weight: 120.11

Section 10 - STABILITY AND REACTIVITY
? Chemical Stability:
Stable.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong bases.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION
? RTECS#:
CAS# 95-44-3 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
L(+)-Threose - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION
?

Section 13 - DISPOSAL CONSIDERATIONS
? Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
?
IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION
?
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 95-44-3: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 95-44-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 95-44-3 is not listed on the TSCA inventory.
It is for research and development use only.

SECTION 16 - ADDITIONAL INFORMATION
N/A