95-86-3 (2,4-二氨基苯酚,2,4-Diaminophenol)

快速询单

结构式：

2,4-二氨基苯酚MOL文件

CAS号：

95-86-3

中文名称：

2,4-二氨基苯酚

英文名称：

2,4-Diaminophenol

分子式：

C₆H₈N₂O

分子量：

124.1405210495

2,4-二氨基苯酚(95-86-3)名称与标识符

名称

中文别名：

2,4-二氨基苯酚;

英文别名：

2,4-Diaminophenol;2,4-Diaminophenol (ACI);4-Hydroxy-1,3-benzenediamine;NS00009579;SB75530;aniline, 3-amino-4-hydroxy-;H691WBT7OS;NSC5727;EINECS 202-459-4;2,4-DIAMINOPHENOL [INCI];Phenol, 2,4-diamino-;2,4-DIAMINOPHENOL [MI];XIWMTQIUUWJNRP-UHFFFAOYSA-;EN300-35023;MFCD00025290;CHEMBL2924225;UNII-H691WBT7OS;DTXSID7043748;95-86-3;Amidol;4-13-00-01425 (Beilstein Handbook Reference);2 pound not4-Diaminophenol;3-amino-4-hydroxyaniline;SCHEMBL27284;NSC-5727;PD118977;DB-226824;BRN 0508475;InChI=1/C6H8N2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H,7-8H2;DTXSID201015761;NCGC00249006-01;STL264251;DTXCID5023748;DS-2112;Q3297000;AKOS015891107;NSC 5727;

标识符

MDL：

MFCD00025290

InChIKey：

XIWMTQIUUWJNRP-UHFFFAOYSA-N

Inchi：

1S/C6H8N2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H,7-8H2

SMILES：

OC1C(N)=CC(N)=CC=1

2,4-二氨基苯酚(95-86-3)物化性质

实验特性

LogP : 1.71900
PSA : 72.27000
折射率 : 1.5745 (estimate)
沸点 : 347.4℃ at 760 mmHg
熔点 : 79°C (rough estimate)
闪点 : 163.9°C
密度 : 1.1683 (rough estimate)

计算特性

精确分子量 : 124.06400
氢键供体数量 : 3
氢键受体数量 : 3
可旋转化学键数量 : 0
同位素质量 : 196.017018
重原子数量 : 9
复杂度 : 97.1
同位素原子数量 : 0
确定原子立构中心数量 : 0
不确定原子立构中心数量 : 0
确定化学键立构中心数量 : 0
不确定化学键立构中心数量 : 0
共价键单元数量 : 3
疏水参数计算参考值（XlogP） : 0.5
拓扑分子极性表面积 : 72.3

2,4-二氨基苯酚(95-86-3)海关数据

海关编码：

2922299090

海关数据：

中国海关编码：

2922299090

概述：

2922299090. 其他氨基(萘酚、酚)及醚、酯〔包括它们的盐, 但含有一种以上含氧基的除外〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

申报要素：

品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

Summary：

2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

2,4-二氨基苯酚(95-86-3)推荐厂家更多厂家(28)

公司名称	手机号/电话	联系人	QQ	询单
湖北摆渡化学有限公司	13517219350 13517219350	彭星	1400878899	询单
上海甄准生物科技有限公司	13816009161 021-68920155	姜经理13816009161	3001086693	询单
湖北巨胜科技有限公司	18871490354	王珊	1400848866	询单
湖北永阔科技有限公司	18771920143 027-59223108	郭经理	1248580055	询单
湖北广奥生物科技有限公司	13657291602 13657291602	郭银	1098480033	询单
湖北鑫红利化工有限公司	15172537016 027-59503710	吕经理	1018283355	询单
湖北万得化工有限公司	15827180502 027-59210159	陈丹丹	1148980033	询单
巨胜化学研究院	18064118002 027-59599240	陈盼	1400838822	询单
湖北实顺生物科技有限公司	15107128801 15107128801	郑雨晗	1400818899	询单
深圳振强生物技术有限公司	13670046396 86-755-66853366	颜经理	2851296953	询单

2,4-二氨基苯酚(95-86-3)合成路线

合成路线：1 步

51-28-5

_100%

95-86-3

反应条件：

1.1 Reagents: Hydrogen Catalysts: Palladium , Silicic acid (H4SiO4), tetraethyl ester, polymer with triethoxymethylsilane Solvents: Methanol ; 1 h, 1 bar, rt

参考文献：

Selective hydrogenation of functionalized nitroarenes under mild conditions

Pandarus, Valerica; Ciriminna, Rosaria; Beland, Francois; Pagliaro, Mario, Catalysis Science & Technology, 2011, 1(9), 1616-1623

合成路线：1 步

51-28-5

_100%

95-86-3

反应条件：

1.1 Reagents: Hydrogen Catalysts: Yttrium sesquioxide , Silver Solvents: Ethanol ; 2 MPa, rt; rt → 140 °C; 3 - 6 h, 2 MPa, 140 °C

参考文献：

Synthesis of Y2O3 nanoband-supported Ag catalyst for hydrogenation of aromatic nitro compounds

, China, , ,

合成路线：1 步

51-28-5

_98%

95-86-3

反应条件：

1.1 Reagents: Sodium borohydride Catalysts: Iron oxide (Fe3O4) , Chitosan , Iron alloy, base, Fe 83-85,W 8.50-9.50,Cr 4.00,Mo 0.90,V 0.60-0.80,C 0.55-0.65,M… Solvents: Water ; 5 min, rt

参考文献：

Facile Synthesis of Magnetic Bentonite-Chitosan-Pd Nanocomposite: As a Recoverable Nanocatalyst for Reduction of Nitroarenes and Suzuki-Miyaura Reaction

Daneshafruz, Haniyeh; Mohammadi, Pourya; Barani, Hossein; Sheibani, Hassan, Journal of Inorganic and Organometallic Polymers and Materials, 2023, 33(4), 1052-1065

合成路线：1 步

119-34-6

_98%

95-86-3

反应条件：

1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Ethanol ; 4 h, 0.1 MPa, rt

参考文献：

Palladium nanoparticles supported on nitrogen-functionalized active carbon: A stable and highly efficient catalyst for the selective hydrogenation of nitro arenes

Li, Zelong; Li, Jinlei; Liu, Jianhua; Zhao, Zelun; Xia, Chungu; et al, ChemCatChem, 2014, 6(5), 1333-1339

合成路线：1 步

149265-55-4

_97%

95-86-3

反应条件：

1.1 Reagents: Sodium borohydride Catalysts: Platinum Solvents: Water ; 2 - 3 h, 25 °C

参考文献：

Immobilization of platinum nanoparticles on the functionalized chitosan particles: an efficient catalyst for reduction of nitro compounds and tandem reductive Ugi reactions

Hamzavi, Seyedeh Fazileh; Jamili, Shahla; Yousefzadi, Morteza; Mashinchian Moradi, Ali; Amrollahi Biuki, Narges, Molecular Diversity, 2020, 24(4), 985-995

合成路线：1 步

51-28-5

_97%

95-86-3

反应条件：

1.1 Solvents: Tetrahydrofuran , Water ; 10 min
1.2 Reagents: Sodium borohydride ; 5 h, 50 - 60 °C

参考文献：

NaBH4/charcoal. A new synthetic method for mild and convenient reduction of nitroarenes

Zeynizadeh, Behzad; Setamdideh, Davood, Synthetic Communications, 2006, 36(18), 2699-2704

合成路线：1 步

51-28-5

_96%

95-86-3

反应条件：

1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Methanol ; 1 h, 0.48 MPa, 65 °C; 0.5 h, 0.85 MPa, 65 °C

参考文献：

Synthesis method of disperse dye intermediate 3-amino-4-methoxyacetanilide from 2,4-dinitrophenol via hydrogenation, etherification and acylation

, China, , ,

合成路线：1 步

51-28-5

_96%

95-86-3

反应条件：

1.1 Reagents: Sodium borohydride Catalysts: Citric acid (loaded on iron oxide) , Iron oxide (Fe3O4) (copper supported citric acid modified) , Copper Solvents: Ethanol , Water ; 5 min, 45 °C

参考文献：

Preparation and characterization of copper chloride supported on citric acid-modified magnetite nanoparticles (Cu2+-CA@Fe3O4) and evaluation of its catalytic activity in the reduction of nitroarene compounds

Ghonchepour, Ehsan ; Yazdani, Elahe; Saberi, Dariush ; Arefi, Marzban; Heydari, Akbar, Applied Organometallic Chemistry, 2017, 31(12),

合成路线：1 步

51-28-5

_95%

95-86-3

反应条件：

1.1 Reagents: Glyoxylic acid , Hydrazine hydrate (1:1) ; rt
1.2 Catalysts: Zinc ; 2 min, rt

参考文献：

A new reagent for selective reduction of nitro group

Raju, B.; Ragul, R.; Sivasankar, B. N., Indian Journal of Chemistry, 2009, (9), 1315-1318

合成路线：1 步

51-28-5

_95%

95-86-3

反应条件：

1.1 Reagents: Formic acid , Hydrazine Solvents: Water
1.2 Reagents: Zinc Solvents: Methanol ; 2 min, rt
1.3 Solvents: Chloroform
1.4 Reagents: Sodium chloride Solvents: Water

参考文献：

Hydrazinium monoformate: A new hydrogen donor. Selective reduction of nitrocompounds catalyzed by commercial zinc dust

Gowda, Shankare; Gowda, B. K. Kempe; Gowda, D. Channe, Synthetic Communications, 2003, 33(2), 281-289

合成路线：1 步

51-28-5

_93%

95-86-3

反应条件：

1.1 Catalysts: Nickel dichloride Solvents: Water ; 20 min, 60 °C
1.2 Reagents: Sodium borohydride ; 5 min, 60 °C

参考文献：

NaBH4/NiCl2·6H2O: a green synthetic method for fast and convenient reduction of nitroarenes in water as green solvent

Hassanloie, Nishtman; Zeynizadeh, Behzad; Ashuri, Shahriar; Hassanloie, Fakhradin, Organic Chemistry: An Indian Journal, 2014, 10(2), 59-62

合成路线：1 步

51-28-5

_93%

95-86-3

反应条件：

1.1 Catalysts: (SP-4-1)-Bis[[2,3-butanedione 2,3-di(oximato-κN)](1-)]copper Solvents: Water ; 10 min, rt
1.2 Reagents: Sodium borohydride ; 17 min, reflux

参考文献：

A green protocol for reduction of aromatic nitro compounds to amines with NaBH4/Cu(dmg)2 system in water as a green solvent

Zeynizadeh, Behzad; Zarrin, Saviz; Ashuri, Shahriar, Organic Chemistry: An Indian Journal, 2013, 9(8), 313-317

合成路线：1 步

51-28-5

_92%

95-86-3

反应条件：

1.1 Reagents: Hydrazine hydrate (1:1) Catalysts: Magnesium Solvents: Methanol ; 50 min, rt

参考文献：

Hydrazine/magnesium mediated cost-effective and selective reduction of nitro compounds

Srinivasa, G. R.; Abiraj, K.; Gowda, D. Channe, Indian Journal of Chemistry, 2003, (11), 2885-2887

合成路线：1 步

51-28-5

_92%

95-86-3

反应条件：

1.1 Reagents: Ammonium formate , Zinc Solvents: Methanol

参考文献：

Zinc-catalyzed ammonium formate reductions: rapid and selective reduction of aliphatic and aromatic nitro compounds

Gowda, D. Channe; Mahesh, B.; Gowda, Shankare, Indian Journal of Chemistry, 2001, (1), 75-77

合成路线：1 步

51-28-5

_92%

95-86-3

反应条件：

1.1 Reagents: Formic acid Catalysts: Palladium Solvents: Methanol

参考文献：

Formic acid with 10% palladium on carbon: a reagent for selective reduction of aromatic nitro compounds

Gowda, D. Channe; Gowda, Shankare, Indian Journal of Chemistry, 2000, (9), 709-711

合成路线：1 步

51-28-5

_90%

95-86-3

反应条件：

1.1 Reagents: Formic acid Solvents: Water ; 10 min, 140 °C

参考文献：

Selective reduction of nitro compounds using CeY zeolite under microwaves

Arya, Kapil; Dandia, Anshu, Journal of the Korean Chemical Society, 2010, 54(1), 55-58

合成路线：1 步

51-28-5

_90%

95-86-3

反应条件：

1.1 Reagents: Ammonium formate Solvents: Water ; 10 min

参考文献：

Selective reduction of nitro compounds using formic acid and RE HY zeolite under microwaves

Arya, Kapil; Agarwal, Manish, Proceedings of ECSOC-10, 2006, ,

合成路线：1 步

51-28-5

_82%

95-86-3

反应条件：

1.1 Reagents: Hydrogen Catalysts: 2761204-70-8 (composite with silica and Pd nanoparticles) Solvents: Water ; 2 h, rt

参考文献：

Pd on imidazolium ionic liquid modified halloysite: A potent catalyst for the hydrogenation of nitro-compounds under mild reaction condition

Sadjadi, Samahe; Koohestani, Fatemeh, Inorganic Chemistry Communications, 2022, 137,

合成路线：1 步

51-28-5

_81%

95-86-3

反应条件：

1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Methanol ; 60 min, 0.2 MPa, 50 °C

参考文献：

Pd-Pt/modified GO as an efficient and selective heterogeneous catalyst for the reduction of nitroaromatic compounds to amino aromatic compounds by the hydrogen source

Salahshournia, Hossein; Ghiaci, Mehran, Applied Organometallic Chemistry, 2019, 33(4),

合成路线：1 步

51-28-5

_81%

95-86-3

参考文献：

Electrolytic reduction of 2,4-dinitrophenol to 2,4-diaminophenol

Dey, B. B.; Maller, R. Krishna; Pai, B. R., Journal of Scientific & Industrial Research, 1948, 7, 71-6