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5-甲基四氢叶酸

CAS No. : 31690-09-2

MCE 国际站：Levomefolic acid

产品活性：Levomefolic acid (5-MTHF) 是一种具有口服活性、可通过血脑屏障的天然叶酸活性形式，最广泛使用的一种叶酸食品补充剂。

研究领域：Metabolic Enzyme/Protease  |  NF-κB  |  Immunology/Inflammation

作用靶点：Endogenous Metabolite  |  Reactive Oxygen Species

结构分类：酮、醛、酸

In Vitro: Levomefolic acid (5-MTHF) shows interaction with residues Glu406, Ile 418, Lys417 and Tyr453, of which Lys 417 and Tyr 453 play a strong physiological role in the interaction between S1 and ACE and may act as a potential inhibitor of the S1:ACE2 interaction of the SARS-CoV-2 virus.
Levomefolic acid (5-MTHF) (50 nM, 72 h) increases intracellular folate metabolite activity by 7-fold better than folic acid by 2-fold in human lymphoblastoid cell line (LCL), and is a good folic acid supplement.

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