CAS:376608-74-1|2-[[(3aR,4S,6R,6aS)-6-[[5-Amino-6-chloro-2-(propylthio)-4-pyrimidinyl]amino]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol

产品货号：A604205
产品名称：2-[[(3aR,4S,6R,6aS)-6-[[5-Amino-6-chloro-2-(propylthio)-4-pyrimidinyl]amino]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol
Synonyms:2-(((3aR,4S,6R,6aS)-6-((5-Amino-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol
CAS号：376608-74-1
分子式：C₁₇H₂₇ClN₄O₄S
Appearance:Off-White to Light Beige Solid
Melting Point:85-88°C
分子量：418.94
Storage:-20°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
应用：2-[[(3aR,4S,6R,6aS)-6-[[5-Amino-6-chloro-2-(propylthio)-4-pyrimidinyl]amino]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol is used as a reagent in the synthesis of Ticagrelor (T437700) derivatives as antiplatelet agents.
参考文献：Zhang, H., et al.: Bioorg. Med. Chem. Lett., 22, 3598 (2012)
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