Fibrinopeptide A Antibody
Cat#：PL0301133
Isotype:Rabbit Polyclonal IgG
Immunogen：Peptide derived from Hu Fibrinogen alpha chain (80-125aa).
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis.
Alternate Names：
A alpha polypeptide; FGA; Fib2; FIBA_Hu; Fibrinogen alpha chain; Fibrinogen alpha/alpha E chain [Precursor]; Fibrinopeptide A.
Specificity Reaction：Hu, Mo, Rat, Dog, Pig, Cow, Hor
Application Notes:WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500
Storage ：
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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