本公司提供科研GCNF生殖细胞核因子GCNF/维甲酸受体相关睾丸受体抗体，抗体质量可靠，订购GCNF生殖细胞核因子GCNF/维甲酸受体相关睾丸受体抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：生殖细胞核因子GCNF/维甲酸受体相关睾丸受体抗体
英文名称：Anti-GCNF
货号：bs-11558R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 54kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：Germ cell nuclear factor (GCNF) is an orphan member of the nuclear receptor gene superfamily that influences neurogenesis and germ cell development. GCNF can homodimerize and bind DNA. GCNF regulates paracrine interaction between the oocyte and somatic cells by regulating the expression of BMP-15 and GDF-9, to affect female fertility. GCNF is present in spermatocytes and round spermatids of adult male mouse testis; northern blot and ribonuclease protection assays have shown GCNF is predominant in the testis. The gene expresses three alternatively spliced transcript variants.Function : Orphan nuclear receptor. Binds to a response element containing the sequence 5'-TCAAGGTCA-3'. May be involved in the regulation of gene expression in germ cell development during gametogenesis.Subcellular Location : Nucleus.Tissue Specificity : Shows highest expression in the germ cells of the adult testis.Similarity : Belongs to the nuclear hormone receptor family. NR6 subfamily.Contains 1 nuclear receptor DNA-binding domain.