本公司提供科研BST1/CD157骨髓基质干细胞抗原1抗体，抗体质量可靠，订购BST1/CD157骨髓基质干细胞抗原1抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：骨髓基质干细胞抗原1抗体
英文名称：Anti-BST1/CD157
货号：bs-6023R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 33kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow, pig, dog, Rb
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：Bone marrow stromal cell antigen 1 (BST1) is a pleiotropic ectoenzyme which belongs to the CD38 family and to the growing number of leukocyte surface molecules known to act independently as both receptors and enzymes. The BST1 molecule displays two distinct domains in its extracellular component. The first is implicated in the enzymic activities of the molecule (it synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores) and the second domain has adhesion/signalling properties.Bone marrow stromal cell antigen 1 facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.Function : Synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth.Subunit : Homodimer.Subcellular Location : Cell membrane; Lipid-anchor, GPI-anchor.Tissue Specificity : Widely expressed.Similarity : Belongs to the ADP-ribosyl cyclase family.