Hemoglobin α Antibody
Cat#：PL0300024
Isotype:Rabbit Polyclonal IgG
Immunogen：Peptide derived from Hu Hemoglobin alpha.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
Alternate Names：
Hemoglobin A1c; Alpha globin; Hba1; HBA2; HBAM; Hemoglobin alpha 1; Hemoglobin alpha adult chain 1; HBA_Hu.
Specificity Reaction：Hu,
Application Notes:WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:50-200
Storage ：
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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