中文名称：肝脏X受体α多克隆抗体

英文名称：LXRα Polyclonal Antibody

产品说明书：http://www.abbkine.cn/product/ABP52874

应用类型：WB# IHC-P# ELISA

背景资料：Oxysterols receptor LXR-alpha encoded by NR1H3 belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR， and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Oxysterols receptor LXR-alpha肝脏X受体α多克隆抗体LXRα Polyclonal Antibody