C3 Antibody
Cat#：PL0301677
Isotype:Rabbit Polyclonal IgG
Immunogen：Peptide derived from human Complement C3 alpha chain.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.
Alternate Names：
Complement C3; stimulating protein cleavage product; ASP; C3 and PZP like alpha 2 macroglobulin domain containing protein 1; Complement C3; Complement component 3; Complement factor 3; CPAMD1; Complement C3 alpha chain; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 2; CO3_HUMAN.
Specificity Reaction：Hu, Mo, Rat, Pig, Cow, Hor, Guinea Pig
Application Notes:WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500
Storage ：
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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