VaxArray® is an immunoassay, imaging, and potency interpretation platform. When the Imaging system is paired with the Influenza Seasonal Hemagglutinin potency assay kit, it creates a semi-automated platform to rapidly perform singleplex and multiplex immunoassays for seasonal hemagglutinin quantification. It can be used at any stage in the vaccine manufacturing process.
With its high specificity, accuracy and speed, potency determination for multiple strains can be obtained in less than 2 hours. The assay is based on a “universal” panel of subtype-specific monoclonal antibodies printed in an array format.
Sample Prep Time: Equivalent to SRID
Assay Time: Less than 2 hours compared to 24 hours for SRID
Data Analysis Time: Automated taking less than 5 minutes
VaxArray® Influenza can be used to quantify HA protein in any influenza vaccine manufacturing or research method and in almost any medium, including crude extract, bulk drug substance, and finished vaccine product. It has been shown to work with split viruses, virus like particles, as well as recombinant HA.
VaxArray is currently being evaluated by the US Department of Health and Human Services as an alternative to single radial immunodiffusion (SRID, also SRD) for vaccine potency determination.
