特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博供应的重组人表皮生长因子受体(EGFR)(HER1 mutant)折扣价用于科研目的生化试验项目,本产品质量好,且极具价格优势,深为用户称道,了解更多重组人表皮生长因子受体(EGFR)(HER1 mutant)等分子生物学试剂产品请联系我司咨询订购。
名称:重组人表皮生长因子受体(EGFR)(HER1 mutant)折扣价
英文名:Recombinant Human Epidermal Growth Factor Receptor/Receptor Tyrosine Protein Kinase ErbB1
产地:国产|进口
规格:10μg|50μg|500μg|1mg
品牌:百奥莱博
编号:JN1439
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Leu25-Val30Gly&Asn298-Ser645在C端带有Fc标签。
EGFR/HER1 mutant质量控制:>95%(还原性SDS-PAGE)
EGFR/HER1 mutant制剂:冻干品
EGFR/HER1 mutant保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
EGFR/HER1 mutant复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于EGFR/HER1 mutant:
The EGFR subfamily of receptor tyrosine kinases is composed of EGFR, ErbB2, ErbB3 and ErbB4. The EGFR shares 43% - 44% aa sequence identity with the ECD of human EGFR subfamily. All these family members are type I transmembrane glycoproteins with an extracellular ligand binding domain. The extracellular ligand binding domain is containing two cysteine-rich domains separated by a spacer region and a cytoplasmic domain containing a membrane-proximal tyrosine kinase domain. Ligand binding could induce EGFR homodimerization and heterodimerization with ErbB2, resulting in cell signaling, heterodimerization tyrosine phosphorylation and kinase activation. It can bind EGF, amphiregulin, TGF-alpha, betacellulin, epiregulin, HB-EGF, epigen, and so on. Its signaling regulates multiple biological functions including cell proliferation, differentiation, motility, and apoptosis. EGFR can also be recruited to form heterodimers with the ligand-activated ErbB3 or ErbB4. EGFR is overexpressed in different tumors. Several anti-cancer drugs use EGFR as target.
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更多有关重组人表皮生长因子受体(EGFR)(HER1 mutant)折扣价的价格及使用说明等,请联系我们的业务经理王欣女士咨询,我公司还销*(代"售")以下产品:
·重组人FGF21(成纤维生长因子21)
编号:JN0232
英文名称:Recombinant Human Fibroblast Growth Factor 21
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备,目的基因编码的His29-Ser209在N端含有His标签
FGF-21质量控制:>95%(还原性SDS-PAGE)。
FGF-21制剂:冻干品
FGF-21保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
FGF-21复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于FGF-21:
Fibroblast Growth Factor 21 (FGF21) is a growth factor that belongs to the FGF family. FGF family proteins play a central role during prenatal development and postnatal growth and regeneration of mamy tissues, by promoting cellular proliferation and differentiation. FGF21 is a potent activator of glucose uptake on adipocytes, protects animal from diet-induced obesity when overexpression in transgenic mice, and lower blood glucose and triglyceride levels when therapeutically adiministered to diabetic redents. FGF21 is produced by hepatocytes in reponse to free fatty acid stimulation of a PPARa/RXR dimeric complex. This situation occurs clinically during starvation, or following the ingestionof a highly-fat/low-carbohydrate diet.Upon FGF21 secretion, white adipose tissue is induced to release free fatty acids from triglyceride stores. Once free fatty acid reach hepatocytes, they are oxidized and reduced to acetyl-CoA. The acetyl-CoA is recombined into 4-carbon ketone bodies, release, and transported to peripheral tissue for TCA processing and energy generation.
重组人表皮生长因子受体(EGFR)(HER1 mutant)折扣价关键词:重组人表皮生长因子受体蛋白,重组人HER1 mutant,重组人EGFR,JN1439
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·重组人信号素5A(Semaphorin 5A)(Sema5A)
编号:JN0591
英文名称:Recombinant Human Semaphorin 5A
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Glu23-Thr765在C端含有His标签。
Semaphorin 5A质量控制:>95%(还原性SDS-PAGE)
Semaphorin 5A制剂:冻干品
Semaphorin 5A保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
Semaphorin 5A复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于Semaphorin 5A:
Semaphorin-5A (SEMA5A) is a member of the Semaphorin family of axon guidance molecules. SEMA5A is a 140 kDa protein. Class 5 Semaphorins are type I transmembrane glycoproteins with an N- terminal Sema domain and multiple juxtamembrane type 1 Thrombospondin (TSP) repeats within their extracellular domains. SEMA5A is expressed in neuroepithelial cells surrounding retinal axons, oligodendrocytes, the base of limb buds, the mesoderm surrounding cranial vessels , and the cardiac atrial septum and endo*(代"c")ardial cushions, Human SEMA5A cDNA encodes a signal sequence, a extracellular domain (ECD), a transmembrane sequence and an cytoplasmic portion. SEMA5A mutations have been implicated in the genetic syndrome,cri-du-chat,while some polymorphisms may increase risk for neurodegenerative diseases such as Parkinson. The expression of SEMA5A may be upregulated in metastatic cancer cells and downregulated in autism.
重组人表皮生长因子受体(EGFR)(HER1 mutant)折扣价关键词:重组人表皮生长因子受体蛋白,重组人HER1 mutant,重组人EGFR,JN1439
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我公司正在优惠促销分子生物学试剂等系列产品,期待您的咨询选购重组人表皮生长因子受体(EGFR)(HER1 mutant)折扣价。