乙醇中毒多发生于饮酒,饮酒后极少量的乙醇被胃黏膜内的乙醇脱氢酶代谢清除,而大部分留于小肠内被迅速扩散吸收至体液中。过量饮酒已被列为世界公共卫生的主要问题之一,可诱发多种疾病,如心血管疾病、消化系统疾病、精神障碍等。急性酒精中毒主要表现为神经行为的改变,导致行。
滕州市浩瀚色谱仪器技术服务有限公司研发出《超高灵敏度气相色谱仪检测血液中酒精含量》，建立全血样品的乙醇毛细管气相色谱快速分析方法。结果在选定的色谱条件下,血中的乙醇能与样品中可能存在的的主要干扰成分实现基线分离。在0.0~300.0 mg/100 mL范围内线性良好,检出限为0.2 mg/100 mL。标准溶液测定的相对标准偏差(RSD)为1.36%,将所建立的方法用于全血样品的分析,加标回收率为90.9%~107.3%,样品测定的RSD为1.98%。该测定方法的合成不确定度为2.2%。结论该法可应用于全血中乙醇的测定,分析周期短且方法简单,适合大批量样品的快速分析。

Ethanol poisoning occurred in alcohol, drinking a very small amount of ethanol by the gastric mucosa of alcohol dehydrogenase metabolism, and most of the small intestine was quickly spread to the body fluid. Excessive drinking has been listed as one of the main problems of world public health, can induce a variety of diseases, such as cardiovascular disease, digestive diseases, mental disorders. Acute alcoholism is mainly manifested as a change in neurobehavior.
Tengzhou City, the vast chromatographic equipment Technology Co., Ltd. developed a "ultra-high sensitivity gas chromatography detection of alcohol content in the blood," the establishment of whole blood samples of ethanol capillary gas chromatography rapid analysis method. Results Under selected chromatographic conditions, ethanol in the blood can be separated from the main interfering components that may be present in the sample. The linear range was 0.0 ~ 300.0 mg / 100 mL, and the detection limit was 0.2 mg / 100 mL. The relative standard deviation (RSD) of the standard solution was 1.36%. The established method was applied to the analysis of whole blood samples. The recoveries were 90.9% ~ 107.3% and the RSD was 1.98%. The synthetic uncertainty of this method was 2.2%. Conclusion The method can be applied to the determination of ethanol in whole blood. The analysis period is short and the method is simple and suitable for rapid analysis of large quantities of samples.