内毒素:
Less than 1.0 EU per μg by the LAL method.

纯度:
>98% as determined by SDS-PAGE.

活性:


产品背景:
Polymeric immunoglobulin receptor (PIGR) is also known as Poly-Ig receptor, which can be cleaved into membrane secretory component (SC). PIGR is a type I transmembrane glycoprotein or a member of the immunoglobulin superfamily, and is synthesized by secretory epithelial cells and delivered to the basolateral plasma membrane where it can bind larger polymers of IgA (pIgA ) and pentameric IgM. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.

产品描述:
Human pIgR, His Tag is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 68.7 kDa. The predicted N-terminus is Lys 19. The reducing (R) protein migrates as 85-95 kDa in SDS-PAGE due to glycosylation.