产品英文名称：
Human Beta 2 Microglobulin
英文简称:
B2M
中文名称:
人β2微球蛋白
背景资料:
es. Very limited amounts of MHC class I molecules can be found on the surface in the absence of ?2 microglobulin. CD8 T cells cannot develop in the absence of MHC class I.Beta 2-microglobulin is present in small amounts in serum， csf， and urine of normal people， and to a much greater degrHuman Beta-2 Microglobulin produced in Human urine from patients with tubular proteinuria having a molecular mass of 12KDa and pI of 5.6. in the urine and plasma of patients with tubular proteinaemia， renal failure， or kidney transplants. Human Beta 2 microglobulin levels can rise either because its rate of synthesis has increased （e.g. in AIDS， malignant monoclonal plasma cell dyscrasia， solid tumors and autoimmune disease） or because of impaired renal filtration （e.g. due to renal insu患有肾小管性蛋白尿病患者的尿液中提取纯化iciency， graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy）. Beta-2 microglobulin levels might also be elevated in multiple myeloma and lymphoma cases. Dialysis-related amyloidosis develops after a long-term hemodialysis， it can aregate into amyloid fibers that deposit in joint spaces.
产品描述:
Human Beta-2 Microglobulin produced in Human urine from patients with tubular proteinuria having a molecular mass of 12KDa and pI of 5.6.
来源宿主:
患有肾小管性蛋白尿病患者的尿液中提取纯化
序列:
溶解建议:
Sterile Filtered White lyophilized （freeze-dried） powder. Lyophilized from 0.02M NH4HCO3. It is recommended to reconstitute the lyophilized HuB2M in phosphate buffer pH > 7.0 containing 0.15M NaCl.
保存建议：
Human B2M although stable at room temperature for 3 weeks， should be stored between 2-8℃.
其他简介：
ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。
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