本公司提供科研Mannan Binding Lectin甘露聚糖结合凝集素抗体，抗体质量可靠，订购Mannan Binding Lectin甘露聚糖结合凝集素抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：甘露聚糖结合凝集素抗体
英文名称：Anti-Mannan Binding Lectin
货号：bs-1582R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 26kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, Rb, rat, cow
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008].Subunit : Oligomeric complex of 3 or more homotrimers. Interacts with MASP1 and MASP2. Interacts with MEP1A and MEP1B and may inhibit their catalytic activity.Subcellular Location : Secreted.Tissue Specificity : Plasma protein produced mainly in the liver.Similarity : Contains 1 C-type lectin domain. Contains 1 collagen-like domain.[FUNCTION]Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.MBL （mannan binding lectin）甘露聚糖结合凝集素，MBL是一种兼有调理素和直接激活补体功能的免疫分子，参与构成抗感染的第一道防线。MBL2在发生急性期反应时由肝脏分泌，并参与天然免疫防御。凝集素配体可以存在于各种各样的微生物中，两者结合后可以导致调理作用并激活补体系统。