本公司提供科研CCR7/CD197细胞表面趋化因子受体7抗体,抗体质量可靠,订购CCR7/CD197细胞表面趋化因子受体7抗体请联系在线客服或者销售人员。 抗体参数如下>>>> 中文名称:细胞表面趋化因子受体7抗体 英文名称:Anti-CCR7/CD197 货号:bs-1305R 抗体来源:兔 克隆类型:多克隆 蛋白分子量:predicted molecular weight: 42kDa 纯化方法:affinity purified by Protein A 交叉反应:mo, rat, hu, dog 测试应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 产品背景介绍:CCR7 is a member of the G protein coupled receptor family (subfamily : chemokine). This receptor was identified as a gene induced by the Epstein Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. CCR7 has been reported to be expressed in blood, bone marrow, lymph node, and intestine. It is particularly expressed in lymphoid tissues and in activated B and T lymphocytes and has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. ESTs have been isolated from blood, embryo, lymph node, and thymus libraries.趋化因子是当今细胞因子研究领域的热点之一,它参与多种免疫及炎症反应,在感染、肿瘤的生长与转移、组织修复及创伤愈合等病理生理过程中发挥重要作用.CCR7在肿瘤的生长与转移方面起到一定的作用.