ADM/AM/Adrenomedullin Antibody
Cat#:PL0300268
Isotype:Rabbit Polyclonal IgG
Immunogen:Peptide derived from Hu ADM N-terminus.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes.
Alternate Names:
Adrenomedullin; ADM; ADM precursor; ADML_Hu.
Specificity Reaction:Hu, Mo, Rat, Dog, Cow, Hor,
Application Notes:WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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