ET-1(2C4) Antibody
Cat#：PL0306928
Isotype:Mouse Monoclonal(2C4) IgG
Immunogen：Peptide derived from human ET-1.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms - ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart, and liver. Endothelin 1 is expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.
Alternate Names：
Big endothelin 1; EDN1; EDN1 protein; Endothelin1; ET1; PPET1; Preproendothelin 1; Preproendothelin1
Specificity Reaction：Hu, Mo, Rat, Dog, Pig, Cow, Hor, Sheep, Guinea Pig
Application Notes:E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500
Storage ：
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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