本公司提供科研CCT2/TCP1 beta分子伴侣复合体TCP-1β抗体，抗体质量可靠，订购CCT2/TCP1 beta分子伴侣复合体TCP-1β抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：分子伴侣复合体TCP-1β抗体
英文名称：Anti-CCT2/TCP1 beta
货号：bs-11267R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 57 kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, Rb, cow, pig, zebrafish
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：CCT2 is one of eight largely unrelated subunit proteins found in a protein chaperone complex known as the chaperonin-containing TCP-1 (CCT) or TRiC complex. The CCT complex is an abundanct cytoslic component that is credited with helping newly synthesized polypeptides adopt the correct conformation (1). Proteins that fold and assemble with the help of CCT include the cytoskeletal proteins actin and tubulin as well as up to 15% of newly synthesized eukaryotic proteins (2). CCT2 is the β-subunit of the chaperone complex and is one of several CCT proteins that exhibit increased expression in response to stress. This implies that the CCT complex helps cells recover from protein damage by assisting in protein folding and assembly (3). CCT subunit levels also change throughout the cell cycle, with lower proteins levels (and reduced chaperone activity) found during induced cell cycle arrest during at M phase (4). Each CCT subunit is thought to perform a specific function during protein folding and assembly (5); CCT2 exhibits both actin and tubulin binding activities (6,3) but the exact molecular function on this subunit remains uncertain.Function : Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.Subcellular Location : Cytoplasm.Similarity : Belongs to the TCP-1 chaperonin family.