ZNF703锌指蛋白703抗体

¥1380 - 2200
LMAI Bio
进口/国产
2021-07-27 14:52

上海联迈生物工程有限公司

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产品属性
供应商上海联迈生物工程有限公司
数量大量
目录编号LM-20145R
克隆性多克隆
抗原来源Rabbit
保质期1年
抗体英文名ZNF703
抗体名锌指蛋白703抗体
宿主Rabbit
适应物种Human, Mouse, Rat,
免疫原KLH conjugated synthetic peptide derived from human ZNF703:221-320/590
亚型IgG
形态Lyophilized or Liquid
应用范围WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
浓度1mg/ml
保存条件Store at -20 °C
规格100ul  200ul
产品说明
ZNF703锌指蛋白703抗体
英文名称ZNF703
中文名称锌指蛋白703抗体
别 名FLJ14299; ZEPPO1; Zinc finger elbow-related proline domain protein 1; Zinc finger protein 703; ZN703_HUMAN; ZNF503L; znf703; ZPO1.
规格价格100ul/1380元 购买 200ul/2200元 购买 大包装/询价
说 明 书100ul 200ul
研究领域肿瘤 转录调节因子 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,
产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量58kDa
细胞定位细胞核 细胞浆
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ZNF703:221-320/590
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMedPubMed
产品介绍Function:
Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through recruitment of histone deacetylases to gene promoters. Regulates cell adhesion, migration and proliferation. May be required for segmental gene expression during hindbrain development.

Subcellular Location:
Nucleus. Cytoplasm

Tissue Specificity:
Expressed in mammary epithelium.

DISEASE:
Amplification of the gene correlates with its protein expression in tumor cells. ZNF703 is a classical breast cancer oncogene since it is able to transform non-malignant cells and increase cellular proliferation.

Similarity:
Belongs to the Elbow/Noc family. 
Contains 1 C2H2-type zinc finger.

SWISS:
Q9H7S9

Gene ID:
80139

Database links:

Entrez Gene: 80139 Human

Entrez Gene: 353310 Mouse

Entrez Gene: 680717 Rat

SwissProt: Q9H7S9 Human

SwissProt: P0CL69 Mouse

Unigene: 726062 Human

Unigene: 212469 Mouse

Unigene: 15384 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
产品图片
Tissue/cell: human breast cancer; 4% Paraformaldehyde-fixed and paraffin-embedded; 
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; 
Incubation: Anti-ZNF703 Polyclonal Antibody, Unconjugated(bs-20145R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining