| 免疫原 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
| 亚型 | IgG2a |
| 形态 | liquid |
| 保存条件 | 12 months -20℃ |
| 克隆性 | 单克隆 |
| 适应物种 | Human |
| 保质期 | 12月 |
| 目录编号 | FNab10143 |
| 级别 | 科研 |
| 数量 | 100 |
| 供应商 | 武汉菲恩生物科技有限公司 |
| 宿主 | Mouse |
| 应用范围 | ELISA, WB, IF |
| 抗体英文名 | NFKB1 antibody |
| 抗体名 | NFKB1 antibody |
| 规格 | 100µg |
| 产品名称 | anti- NFKB1 antibody | |
| 货号 | FNab10143 | |
| 规格 | 100µg | |
| 状态 | liquid | |
| 纯化方法 | Protein A+G purification | |
| 纯度 | ≥95% as determined by SDS-PAGE | |
| 宿主 | Mouse | |
| 亚型 | IgG2a | |
| 存储 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) | |
| 背景介绍 | This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed. | |
| 免疫原 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | |
| 别称 | NMT | |
| 分子量 | 105 kDa/50 kDa | |
| Uniprot ID | P19838 | |
| 适用种属 | Human | |
| 验证应用 | ELISA, WB, IF | |
| 建议稀释比例 | WB: 1:500 - 1:3000; IF: 1:20 - 1:200 | |
| 图片 |  | |
 | MCF7 cells were subjected to SDS PAGE followed by western blot with FNab10143(NFKB1 antibody) at dilution of 1:1000 | |
| 注意事项 | NFKB1 antibody|NFKB1抗体仅供科研使用 | |
