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| 免疫原 | Amino acids 51 – 140 of human EndoG. |
| 亚型 | mouse IgG1 |
| 形态 | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.02% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存条件 | Store at 4°C. |
| 克隆性 | 单克隆 |
| 标记物 | 见下方详细说明 |
| 适应物种 | H, M, R |
| 保质期 | 1-2年 |
| 抗原来源 | Amino acids 51 – 140 of human EndoG. |
| 目录编号 | 253260 |
| 级别 | 超纯 |
| 数量 | 大量 |
| 供应商 | Abbiotec |
| 宿主 | Mouse |
| 应用范围 | E, WB |
| 浓度 | 见详细说明信息 |
| 靶点 | EndoG (7F2D7) |
| 抗体英文名 | EndoG (7F2D7) Antibody |
| 抗体名 | EndoG (7F2D7) Antibody |
| 规格 | 0.1 mg |
| 产品名称： | EndoG (7F2D7) Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 253260 |
| 规格： | 0.1 mg |
| 产品描述： | The fragmentation of nuclear DNA is a hallmark of apoptotic cell death. The activities of caspase and nuclease are involved in the DNA fragmentation. Caspase-activated deoxyribonuclease (CAD), also termed DNA fragmentation factor (DFF40), is one such nuclease, and is capable of inducing DNA fragmentation and chromatin condensation after cleavage by caspase-3 of its inhibitor ICAD/DFF45. Caspase and CAD independent DNA fragmentation also exists. Recent studies demonstrated that another nuclease, endonuclease G (EndoG), is specifically activated by apoptotic stimuli and is able to induce nucleosomal fragmentation of DNA independently of caspase and DFF/CAD. EndoG is a mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis. The homologue of mammalian EndoG is the first mitochondrial protein identified to be involved in apoptosis in C. elegans. EndoG also cleaves DNA in vitro. |
| 克隆类型： | Mouse Monoclonal Antibody |
| 亚型： | mouse IgG1 |
| 免疫原： | Amino acids 51 – 140 of human EndoG. |
| 适用物种： | H, M, R |
| 应用范围： | E, WB |
| 应用说明： | E: 1:500-1:1,000; WB: 1:100-1:500 |
| 别名： | EndoG: Endonuclease G |
| 形态： | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.02% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存条件： | Store at 4°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
