本公司提供科研Langerin/CD207白细胞分化抗原CD207抗体，抗体质量可靠，订购Langerin/CD207白细胞分化抗原CD207抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：白细胞分化抗原CD207抗体
英文名称：Anti-Langerin/CD207
货号：bs-2650R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 36kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Langerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.Subunit : Homotrimer.Subcellular Location : Membrane; Single-pass type II membrane protein. Note=Found in Birbeck granules (BGs), which are organelles consisting of superimposed and zippered membranes.Tissue Specificity : Exclusively expressed by Langerhans cells. Expressed in astrocytoma and malignant ependymoma, but not in normal brain tissues.Similarity : Contains 1 C-type lectin domain.