Human Properdin Protein, His Tag

¥3500 - 23100
ACROBiosystems
USA,China
2021-07-31 18:40

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产品属性
英文名Human Properdin Protein, His Tag
供应商ACROBiosystems
规格1mg/100ug
产品说明
内毒素:
Less than 1.0 EU per μg by the LAL method.

纯度:
>90% as determined by SDS-PAGE.

活性:
n/a

产品背景:
Properdin is also known as Complement factor P, CFP, PFC, a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin is produced by many different leukocyte subsets and circulates as cyclic oligomers of monomeric subunits. Properdin on platelet/granulocyte aggregates(PGA) formation are tightly regulated by Factor H, properdin enhances PGA formation via increased production of C5a, and that inhibition of properdin function has therapeutic potential to limit thromboinflammation in diseases characterized by increased PGA formation.

产品描述:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 50.7 kDa. The protein migrates as 55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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