| 克隆性 | 多克隆 |
| 宿主 | Rabbit |
| 适应物种 | Human,Mouse,Rat |
| 亚型 | IgG |
| 形态 | Lyophilized or Liquid |
| 应用范围 | WB,IF,ELISA |
| 保存条件 | -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 规格 | 10μl/20μl/50μl/100μl |
Product name | TIMP2 Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,IF,ELISA |
Species reactivity | Human,Mouse,Rat |
Host Species | Rabbit |
Purity | Affinity purification |
Immunogen Information：
Immunogen | A synthetic peptide of human TIMP2 |
Calculated molecular weight | 24kDa |
Observed molecular weight | 26kDa |
Swiss Prot | P16035 |
Gene ID (NCBI) | 7077 |
Alternative Names | TIMP2; CSC-21K; DDC8; metalloproteinase inhibitor 2 |
Application Notes：
WB | 1:500 - 1:2000 |
IF | 1:50 - 1:200 |
Western blot analysis of extracts of various cell lines, using TIMP2 antibody. | Immunofluorescence analysis of MCF-7 cells using TIMP2 antibody. |
Background：
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
Storage：
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
