| 英文名 | Recombinant Human Parathyroid Hormone (1-84) |
| 数量 | 大量 |
| 规格 | 100μg |
| Species | Gene ID | Accession | Source | Length | MW | Tag |
| Human | 5741 | P01270 | E. coli | 84aa | 9.4kDa | － |
| About this Protein | |
| Name | Recombinant Human PTH1-84 (Recombinant Human Parathyroid Hormone 1-84; rHuPTH1-84)；重组人甲状旁腺素1-84 |
| Synonyms | Parathyroid hormone; PTH; Parathormone; Parathyrin; PTH |
| Purity | >97% by SDS-PAGE and HPLC analyses. |
| Biological Activity | Fully biologically active when compared to standard. The ED50 as determined by its ability to induce cAMP accumulation in murine MC3T3E1 cells is less than 50ng/ml, corresponding to a specific activity of >2.0×104IU/mg. |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation | Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4. |
| Endotoxin | Less than 1EU/μg of rHuPTH1-84 as determined by LAL method. |
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions. |
| Category | Hormones |
| Background | Parathyroid hormone (PTH) is a single polypeptide of 84 amino acids. It is a critical hormone in the regulation of Ca2+ homeostasis and secreted by the parathyroid glands, which promote release of calcium from bone to extracellular fluid by activating osteoblasts and inhibiting osteoclasts, indirectly promote increased intestinal absorption of calcium, and promote renal tubular reabsorption of calcium and increased renal excretion of phosphates. It is a major regulator of bone metabolism. Secretion of parathyroid hormone increases when the level of calcium in the extracellular fluid is low. |
| Amino Acid Sequence | SVSEIQLMHN LGKHLNSMER VEWLRKKLQD VHNFVALGAP LAPRDAGSQR PRKKEDNVLV ESHEKSLGEA DKADVNVLTK AKSQ |
包装清单:
| 产品编号 | 产品名称 | 包装 |
| P6960-20μg | Recombinant Human PTH1-84 | 20μg |
| P6960-100μg | Recombinant Human PTH1-84 | 100μg |
| P6960-1mg | Recombinant Human PTH1-84 | 1mg |
