FITC标记的真核翻译起始因子2C3抗体

¥2980
LMAI Bio
中国/美国/欧洲
2021-08-05 15:46

上海联迈生物工程有限公司

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产品属性
供应商上海联迈生物工程有限公司
数量大量
靶点详见说明书
级别1
目录编号LM-12517R-FITC
克隆性多克隆
抗原来源Rabbit
保质期1年
抗体英文名Anti-Argonaute 3/FITC
抗体名Anti-Argonaute 3/FITC
标记物FITC标记
宿主Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Danio rerio
适应物种Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Danio rerio
免疫原详见说明书
亚型IGg
形态粉末、液体、冻干粉
应用范围ICC=1:50-200 IF=1:50-200
浓度1mg/ml
保存条件-20 °C
规格100ul
产品说明
FITC标记的真核翻译起始因子2C3抗体
英文名称Anti-Argonaute 3/FITC
中文名称FITC标记的真核翻译起始因子2C3抗体
别 名eIF2C3; Argonaute 3/eIF2C 3; 5730550L01Rik; Ago 3; Ago3; AGO3_HUMAN; argonaute 3; Argonaute3; eIF 2C 3; eIF-2C 3; eIF2C 3; Eif2c3; eIF2C3; EIF2C3 protein; Eukaryotic translation initiation factor 2C 3; Eukaryotic translation initiation factor 2C3; FLJ12765; hAgo3; MGC86946; Protein argonaute-3.
规格价格100ul/2980元 购买 大包装/询价
说 明 书100ul
研究领域细胞生物 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Danio rerio
产品应用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量97kDa
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Argonaute 3/eIF2C3
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍background:
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Function:
Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

Subunit:
Interacts with EIF4B, IMP8, PRMT5 and TNRC6B. Interacts with APOBEC3F, APOBEC3G and APOBEC3H. 

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the argonaute family. Ago subfamily.
Contains 1 PAZ domain.
Contains 1 Piwi domain.

Database links:

Entrez Gene: 192669 Human

Entrez Gene: 214150 Mouse

Entrez Gene: 313593 Rat

Omim: 607355 Human

SwissProt: Q9H9G7 Human

SwissProt: Q8CJF9 Mouse

Unigene: 657659 Human

Unigene: 440915 Mouse

Unigene: 482388 Mouse

Unigene: 483093 Mouse

Unigene: 92025 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.