FITC标记的RNA结合蛋白9抗体

¥2980
LMAI Bio
中国/美国/欧洲
2021-08-05 16:40

上海联迈生物工程有限公司

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产品属性
供应商上海联迈生物工程有限公司
数量大量
靶点详见说明书
级别1
目录编号LM-12299R-FITC
克隆性多克隆
抗原来源Rabbit
保质期1年
抗体英文名Anti-Fox2/FITC
抗体名Anti-Fox2/FITC
标记物FITC标记
宿主Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
适应物种Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
免疫原详见说明书
亚型IGg
形态粉末、液体、冻干粉
应用范围ICC=1:50-200 IF=1:50-200
浓度1mg/ml
保存条件-20 °C
规格100ul
产品说明
FITC标记的RNA结合蛋白9抗体
英文名称Anti-Fox2/FITC
中文名称FITC标记的RNA结合蛋白9抗体
别 名RBM9; HRNBP2; Fox 1 homologue; Fox-1 homolog B; FOX2; FXH; Hexaribonucleotide-binding protein 2; HNRBP2; RBFOX2; Repressor of tamoxifen transcriptional activity; RFOX2_HUMAN; RNA binding motif protein 9; RNA binding protein 9; RNA binding protein fox-1 homolog 2; RNA-binding motif protein 9; RNA-binding protein 9; RTA; FOX2.
规格价格100ul/2980元 购买 大包装/询价
说 明 书100ul
研究领域神经生物学 转录调节因子 结合蛋白 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
产品应用ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量41kDa
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from Human Fox2/RBM9
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍background:
This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis (By similarity). RNA-binding protein that seems to act as a coregulatory factor of ER-alpha.

Subunit:
Interacts with ER-alpha N-terminal activation domain. 

Subcellular Location:
Nucleus. Cytoplasm.

Similarity:
Contains 1 RRM (RNA recognition motif) domain.

Database links:

Entrez Gene: 23543 Human

Entrez Gene: 93686 Mouse

Omim: 612149 Human

SwissProt: O43251 Human

SwissProt: Q8BP71 Mouse

Unigene: 282998 Human

Unigene: 202774 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.