本公司提供科研ILP2抑制细胞凋亡样蛋白2抗体，抗体质量可靠，订购ILP2抑制细胞凋亡样蛋白2抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：抑制细胞凋亡样蛋白2抗体
英文名称：Anti-ILP2
货号：bs-6870R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 26kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：Protects against apoptosis mediated by BAX.Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2 (1). ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues (1). ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9. Function : Protects against apoptosis mediated by BAX.Subunit : Binds to caspase-9.Subcellular Location : Cytoplasm (Probable).Tissue Specificity : Testis specific in normal tissues.Similarity : Belongs to the IAP family.Contains 1 BIR repeat.Contains 1 RING-type zinc finger.