SARS-CoV-2 S纳米抗体价格,详情介绍-960化工网

SARS-CoV-2 S纳米抗体

价格：¥4800

品牌：CUSABIO

产地：CN

最新更新日期：2021-08-10 11:55

我要询单 QQ交流

武汉华美生物工程有限公司CUSABIO®

我要认领

公司：武汉华美生物工程有限公司CUSABIO®

联系人：小酷客服

联系电话： 027-87939808

联系邮箱：cusabio@163.com

QQ： 2936043571

产品属性

抗体名

S/RBD

抗体英文名

SARS-CoV-2 RBD Nanobody

靶点

浓度

1mg/ml

应用范围	ELISA, GICA

供应商

武汉华美生物

适应物种	Human Novel Coronavirus (SARS-CoV-2/ 2019-nCoV)

克隆性

单克隆

保存条件	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

形态

Liquid

亚型	VHH fusion with human IgG1 Fc

免疫原	Recombinant Human Novel Coronavirus Spike glycoprotein(S) (319-541aa) (CSB-YP3324GMY1 and CSB-MP3324GMY1b1)

规格

100ul

产品说明

别名:
Anti-coronavirus spike Antibody; Anti-cov spike Antibody; Anti-ncov RBD Antibody; Anti-ncov S1 Antibody;Anti-ncov spike Antibody; Anti-novel coronavirus RBD Antibody; Anti-novel coronavirus S1 Antibody; Anti-novel coronavirus spike Antibody; Anti-RBD Antibody; Anti-S1 Antibody; Anti-Spike RBD Antibody; E2 Antibody; E2 glycoprotein Antibody; Human coronavirus spike glycoprotein Antibody; S Antibody; SARS-CoV-2 S1 RBD Antibody; S glycoprotein Antibody; Spike glycoprotein Antibody
种属:
Human Novel Coronavirus (SARS-CoV-2/ 2019-nCoV)
免疫原:
Recombinant Human Novel Coronavirus Spike glycoprotein(S) (319-541aa) (CSB-YP3324GMY1 and CSB-MP3324GMY1b1)
种属反应性:
Human Novel Coronavirus (SARS-CoV-2/ 2019-nCoV)
应用范围:
ELISA, GICA, Neutralising; Recommended dilution: ELISA:1:10000-1:100000, GICA:1:10000-1:40000, Neutralising:1:100-1:10000
克隆类型:
Monoclonal
抗体亚型:
VHH fusion with human IgG1 Fc
纯化方式:
Affinity-chromatography
标记方式:
Non-conjugated
保存缓冲液:
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式:
Liquid
储存条件:
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
图片:
The Binding Activity of SARS-CoV-2 Spike RBD Nanobody with SARS-CoV-2-S1-RBD

Activity: Measured by its binding ability in a functional ELISA. Immobilized SARS-CoV-2-S1-RBD (CSB-YP3324GMY1) at 2 μg/ml can bind SARS-CoV-2 Spike RBD Nanobody, the EC₅₀ is 0.8674 ng/ml.
In the Colloidal Gold Immunochromatography Assay

detection system, the background of antibody (CSB-RA33245A2GMY) is clean, the detection limit can be as low as 25ng/ml (1.75ng/0.07ml), and the sensitivity is very good.
Binding signal of SARS-CoV-2 Spike RBD Nanobody (CSB-RA33245A2GMY) and SARS-CoV-2-S1-RBD (CSB-YP3324GMY1) was inhibited by ACE2 protein-HRP conjugated inhibitor (CSB-MP866317HU) with the IC₅₀ is 1.296 nM.
Binding signal of SARS-CoV-2 Spike RBD Nanobody (CSB-RA33245A2GMY) and SARS-CoV-2-S1-RBD (CSB-YP3324GMY1) was inhibited by ACE2 protein-HRP conjugated inhibitor (CSB-MP866317HU) with the IC₅₀ is 0.1074 μg/ml.
说明书:
注：产品说明书可能有改进，请直接与CUSABIO产品专员联系，索取最新版说明书！
Accession No.:
P0DTC2
指标名称:
S
研究领域:
Microbiology
克隆号:
A1
产品描述:
This SARS-CoV-2 Spike RBD Nanobody is a recombinant monoclonal antibody generated through the expression of a DNA sequence inserting a human IgG1 Fc domain at the C-terminus, in human embryonic kidney 293 cells (HEK293). The DNA sequence encodes the SARS-CoV-2 spike receptor-binding domain (RBD). The antibody is purified by protein G in vitro. It has been validated with high reactivity towards SARS-CoV-2-S1-RBD by a functional ELISA and good sensitivity for human SARS-CoV-2 spike glycoprotein (S protein) via the Colloidal Gold Immunochromatography Assay (GICA). In neutralization assay, the binding signal of SARS-CoV-2 Spike RBD Nanobody was inhibited by ACE2 protein-HRP conjugated inhibitor, with a 0.1074 μg/ml IC50. Specifically binding and recognizing the RBD of the SARS-CoV-2 spike glycoprotein (S protein), so the SARS-CoV-2 Spike RBD Nanobody can react with samples infected with human coronavirus SARS-CoV-2. But it does not respond to MERS or SARS-CoV spike protein. Akin to other nanobodies, this recombinant nanobody is small and stable, which allows for its reaching to hidden epitopes such as crevices of target proteins.