产品货号 : jlcR5815
英文名称 : RAIDD
中文名称 : CASP2凋亡相关蛋白抗体
别名 : CASP2 and RIPK1 domain containing adaptor with death domain; Caspase and RIP adapter with death domain; Caspase and RIP adaptor with death domain; CRADD; CRADD_HUMAN; Death adaptor molecule RAIDD; Death domain containing protein CRADD; Death domain-containing protein CRADD; MGC9163; RIP associated ICH1/CED3 homologous protein with death domain; RIP associated protein with a death domain; RIP-associated ICH1/CED3-homologous protein with death domain; RIP-associated protein with a death domain.
研究领域 : 肿瘤细胞生物免疫学细胞凋亡
抗体来源 : Rabbit
克隆类型 : Polyclonal
交叉反应 : Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
产品应用 : WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分子量 : 22kDa
细胞定位 : 细胞核细胞浆
性状 : Lyophilized or Liquid
浓度 : 1mg/ml
免疫原 : KLH conjugated synthetic peptide derived from human RAIDD:31-130/199
亚型 : IgG
纯化方法 : affinity purified by Protein A
储存液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
产品介绍 : Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.
Subunit:
Interacts with LRDD.
Tissue Specificity:
Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.
Similarity:
Contains 1 CARD domain.
Contains 1 death domain.
SWISS:
P78560
Gene ID:
8738
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
